| Entry |
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| Name |
6-deoxy-6-sulfo-D-fructose transketolase;
6-deoxy-6-sulfo-erythrulose transketolase;
sqwGH (gene name)
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| Class |
Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases
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| Sysname |
6-deoxy-6-sulfo-D-fructose:D-glyceraldehyde-3-phosphate glycolaldehydetransferase
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| Reaction(IUBMB) |
(1) 6-deoxy-6-sulfo-D-fructose + D-glyceraldehyde-3-phosphate = D-xylulose-5-phosphate + 4-deoxy-4-sulfo-D-erythrose [RN: R13000];
(2) 4-deoxy-4-sulfo-D-erythrulose + D-glyceraldehyde-3-phosphate = D-xylulose-5-phosphate + sulfoacetaldehyde [RN: R13001]
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| Reaction(KEGG) |
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| Substrate |
6-deoxy-6-sulfo-D-fructose [CPD: C20830];
D-glyceraldehyde-3-phosphate;
4-deoxy-4-sulfo-D-erythrulose [CPD: C22511]
|
|---|
| Product |
D-xylulose-5-phosphate;
4-deoxy-4-sulfo-D-erythrose [CPD: C22510];
sulfoacetaldehyde [CPD: C00593]
|
|---|
| Comment |
The enzyme, characterized from the bacterium Clostridium sp. MSTE9, is involved in a D-sulfoquinovose degradation pathway.
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| History |
EC 2.2.1.15 created 2022
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| Pathway |
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| Orthology |
| K28644 | 6-deoxy-6-sulfo-D-fructose transketolase subunit SqwG |
| K28645 | 6-deoxy-6-sulfo-D-fructose transketolase subunit SqwH |
|
|---|
| Genes |
| CLB: | Clo1100_2827 Clo1100_2828 |
| RPAY: | P0092_15955 P0092_15960 |
| TBZ: | BK011_09260 BK011_09265 |
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| Reference |
1 |
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| Authors |
Liu J, Wei Y, Ma K, An J, Liu X, Liu Y, Ang EL, Zhao H, Zhang Y. |
|---|
| Title |
Mechanistically diverse pathways for sulfoquinovose degradation in bacteria. |
|---|
| Journal |
ACS Catal 11:14740-14750 (2021) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.2.1.15 |
| ExPASy - ENZYME nomenclature database: | 2.2.1.15 |
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| LinkDB |
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