ENZYME: 2.3.1.151
Help
Entry
EC 2.3.1.151 Enzyme
Name
2,3',4,6-tetrahydroxybenzophenone synthase;
benzophenone synthase (ambiguous);
BPS (ambiguous)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase (decarboxylating, 2,3',4,6-tetrahydroxybenzophenone-forming)
Reaction(IUBMB)
3 malonyl-CoA + 3-hydroxybenzoyl-CoA = 4 CoA + 2,3',4,6-tetrahydroxybenzophenone + 3 CO2 [RN:
R04709
]
Reaction(KEGG)
R04709
Reaction
Substrate
malonyl-CoA [CPD:
C00083
];
3-hydroxybenzoyl-CoA [CPD:
C05195
]
Product
CoA [CPD:
C00010
];
2,3',4,6-tetrahydroxybenzophenone [CPD:
C06355
];
CO2 [CPD:
C00011
]
Comment
Involved in the biosynthesis of plant xanthones. Benzoyl-CoA can replace 3-hydroxybenzoyl-CoA (cf. EC
2.3.1.220
, 2,4,6-trihydroxybenzophenone synthase).
History
EC 2.3.1.151 created 1999, modified 2013
Reference
1 [PMID:
8925910
]
Authors
Beerhues L.
Title
Benzophenone synthase from cultured cells of Centaurium erythraea.
Journal
FEBS Lett 383:264-6 (1996)
DOI:
10.1016/0014-5793(96)00265-7
Other DBs
ExplorEnz - The Enzyme Database:
2.3.1.151
IUBMB Enzyme Nomenclature:
2.3.1.151
ExPASy - ENZYME nomenclature database:
2.3.1.151
BRENDA, the Enzyme Database:
2.3.1.151
CAS:
175780-21-9
LinkDB
All DBs
DBGET
integrated database retrieval system