KEGG ENZYME: 2.3.1.315

ENZYME: 2.3.1.315

Entry

EC 2.3.1.315                Enzyme

Name

succinyl-CoA:cyclohexane-1-carboxylate CoA transferase;
Gmet_3304 (locus name)

Class

Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups

Sysname

succinyl-CoA---cyclohexane-1-carboxylate CoA-transferase

Reaction(IUBMB)

succinyl-CoA + cyclohexane-1-carboxylate = succinate + cyclohexane-1-carbonyl-CoA [RN:R13299]

Reaction(KEGG)

R13299

Substrate

succinyl-CoA [CPD:C00091];
cyclohexane-1-carboxylate [CPD:C09822]

Product

succinate [CPD:C00042];
cyclohexane-1-carbonyl-CoA [CPD:C09823]

Comment

The enzyme, characterized from the bacterium Geobacter metallireducens, participates in an anaerobic degradation pathway for cyclohexane-1-carboxylate. In vitro, the enzyme can use butanoyl-coA as a CoA donor with greater efficiency than succinyl-CoA.

History

EC 2.3.1.315 created 2024

Reference

1 [PMID:25112478]

Authors

Kung JW, Meier AK, Mergelsberg M, Boll M.

Title

Enzymes involved in a novel anaerobic cyclohexane carboxylic acid degradation pathway.

Journal

J Bacteriol 196:3667-74 (2014)
DOI:10.1128/JB.02071-14

Sequence

[gme:Gmet_3304]