KEGG   ENZYME: 2.4.1.373
Entry
EC 2.4.1.373                Enzyme                                 
Name
alpha-(1->2) branching sucrase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
sucrose:(1->6)-alpha-D-glucan 2-alpha-D-glucosyl-transferase
Reaction(IUBMB)
sucrose + a (1->6)-alpha-D-glucan = D-fructose + a (1->6)-alpha-D-glucan containing a (1->2)-alpha-D-glucose branch [RN:R12528]
Reaction(KEGG)
R12528
Substrate
sucrose [CPD:C00089];
(1->6)-alpha-D-glucan
Product
D-fructose [CPD:C00095];
(1->6)-alpha-D-glucan containing a (1->2)-alpha-D-glucose branch [CPD:C22230]
Comment
The glucansucrases transfer a D-glucosyl residue from sucrose to a glucan chain. They are classified based on the linkage by which they attach the transferred residue. In some cases, in which the enzyme forms more than one linkage type, classification relies on the relative proportion of the linkages that are generated. This enzyme introduces alpha(1->2) branches into (1->6)-alpha-D-glucans.
History
EC 2.4.1.373 created 2019
Orthology
K23981  alpha-(1->2) branching sucrase
Reference
1  [PMID:15601714]
  Authors
Fabre E, Bozonnet S, Arcache A, Willemot RM, Vignon M, Monsan P, Remaud-Simeon M
  Title
Role of the two catalytic domains of DSR-E dextransucrase and their involvement in the formation of highly alpha-1,2 branched dextran.
  Journal
J Bacteriol 187:296-303 (2005)
DOI:10.1128/JB.187.1.296-303.2005
Reference
2  [PMID:23544576]
  Authors
Brison Y, Laguerre S, Lefoulon F, Morel S, Monties N, Potocki-Veronese G, Monsan P, Remaud-Simeon M
  Title
Branching pattern of gluco-oligosaccharides and 1.5kDa dextran grafted by the alpha-1,2 branching sucrase GBD-CD2.
  Journal
Carbohydr Polym 94:567-76 (2013)
DOI:10.1016/j.carbpol.2013.01.064
Reference
3  [PMID:25756290]
  Authors
Passerini D, Vuillemin M, Ufarte L, Morel S, Loux V, Fontagne-Faucher C, Monsan P, Remaud-Simeon M, Moulis C
  Title
Inventory of the GH70 enzymes encoded by Leuconostoc citreum NRRL B-1299 - identification of three novel alpha-transglucosylases.
  Journal
FEBS J 282:2115-30 (2015)
DOI:10.1111/febs.13261
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.373
IUBMB Enzyme Nomenclature: 2.4.1.373
ExPASy - ENZYME nomenclature database: 2.4.1.373
BRENDA, the Enzyme Database: 2.4.1.373
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