KEGG   ENZYME: 2.4.1.377
Entry
EC 2.4.1.377                Enzyme                                 
Name
dTDP-Rha:alpha-D-Gal-diphosphoundecaprenol alpha-1,3-rhamnosyltransferase;
wbaN (gene name);
rfbN (gene name)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
dTDP-beta-L-rhamnose:alpha-D-galactosyl-diphospho-ditrans,octacis-undecaprenol 3-alpha-rhamnosyltransferase (configuration-inverting)
Reaction(IUBMB)
dTDP-beta-L-rhamnose + alpha-D-galactosyl-diphospho-ditrans,octacis-undecaprenol = dTDP + alpha-L-Rha-(1->3)-alpha-D-Gal-PP-Und [RN:R12739]
Reaction(KEGG)
R12739(G)
Substrate
dTDP-beta-L-rhamnose [CPD:C03319];
alpha-D-galactosyl-diphospho-ditrans,octacis-undecaprenol
Product
dTDP [CPD:C00363];
alpha-L-Rha-(1->3)-alpha-D-Gal-PP-Und
Comment
The enzyme, characterized from several Salmonella strains, participates in the biosynthesis of the repeat unit of O antigens produced by strains that belong to the A, B, D and E groups.
History
EC 2.4.1.377 created 2021
Orthology
K12992  O-antigen biosynthesis alpha-1,3-rhamnosyltransferase
Genes
STY: STY2294(rfbN)
STT: t0788(rfbN)
SEX: STBHUCCB_8400
SENT: TY21A_03995
STM: STM2085(rfbN)
SEO: STM14_2579(rfbN)
SEV: STMMW_21161
SEY: SL1344_2062(rfbN)
SEM: STMDT12_C21070
SEJ: STMUK_2115(rfbN)
SEB: STM474_2170(rfbN)
SEF: UMN798_2253(rfbN)
SETU: STU288_06810
SETC: CFSAN001921_06360
SENR: STMDT2_20591(rfbN)
SEND: DT104_21441(rfbN)
SENI: CY43_11250
SEEN: SE451236_16635
SPT: SPA0786(rfbN)
SEK: SSPA0736
SPQ: SPAB_00946
SEH: SeHA_C2311
SHB: SU5_02679
SENH: CFSAN002069_21395
SEEH: SEEH1578_19705
SEW: SeSA_A2313
SEA: SeAg_B2210
SENS: Q786_10295
SED: SeD_A2424
SEG: SG2115(rfbN)
SEL: SPUL_0813(rfbN)
SEGA: SPUCDC_0813(rfbN)
SET: SEN2084(rfbN)
SENA: AU38_10515
SENO: AU37_10525
SENV: AU39_10525
SENQ: AU40_11780
SENL: IY59_10810
SENJ: CFSAN001992_01005
SEEP: I137_03655
KIE: NCTC12125_00633
PAKH: B0X70_24685
PLUI: CE143_24725
PKJ: Q1W70_07740
AEL: NCTC12917_02814
TAU: Tola_2045
CDIZ: CEDIAZO_02901
RAP: RHOA_2855(rfbN)
SFOL: H3H32_28460
 » show all
Reference
1  [PMID:7684736]
  Authors
Liu D, Haase AM, Lindqvist L, Lindberg AA, Reeves PR.
  Title
Glycosyl transferases of O-antigen biosynthesis in Salmonella enterica: identification and characterization of transferase genes of groups B, C2, and E1.
  Journal
J Bacteriol 175:3408-13 (1993)
DOI:10.1128/JB.175.11.3408-3413.1993
  Sequence
[stm:STM2085]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.377
IUBMB Enzyme Nomenclature: 2.4.1.377
ExPASy - ENZYME nomenclature database: 2.4.1.377
BRENDA, the Enzyme Database: 2.4.1.377
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