| Entry |
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| Name |
NADH kinase;
reduced nicotinamide adenine dinucleotide kinase (phosphorylating);
DPNH kinase;
reduced diphosphopyridine nucleotide kinase;
NADH kinase
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
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| Sysname |
ATP:NADH 2'-phosphotransferase
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| Reaction(IUBMB) |
ATP + NADH = ADP + NADPH [RN: R00105]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
CTP, ITP, UTP and GTP can also act as phosphate donors (in decreasing order of activity). The enzyme is specific for NADH. Activated by acetate.
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| History |
EC 2.7.1.86 created 1976 (EC 2.7.1.96 created 1978, incorporated 1978)
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| Orthology |
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| Genes |
| CGR: | 2888057(GVI51_G02761) |
| NCS: | NCAS_0H01000(NCAS0H01000) |
| NDI: | NDAI_0F02290(NDAI0F02290) |
| TPF: | TPHA_0J02240(TPHA0J02240) |
| TBL: | TBLA_0B05170(TBLA0B05170) |
| TDL: | TDEL_0G01590(TDEL0G01590) |
| KAF: | KAFR_0B06770(KAFR0B06770) |
| KNG: | KNAG_0M00410(KNAG0M00410) |
| LBG: | 92208375(LODBEIA_P31790) |
| CAL: | CAALFM_C307010WA(POS5) |
| ASAU: | 88175174(PUMCH_004112) |
| YLI: | 2911693(YALI2_E00361g) |
| NTE: | NEUTE1DRAFT128131(NEUTE1DRAFT_128131) |
| SMP: | 10804274(SMAC4_05136) |
| RTHE: | 98124801(VTJ83DRAFT_3745) |
| TATV: | 25777627(TrAtP1_010778) |
| TASP: | 36613948(TrAFT101_009306) |
| UVI: | 66061641(UV8b_00863) |
| PLJ: | 28883866(PLICBS_005171) |
| DCON: | 63716798(DCS_04155) |
| CDET: | 87951487(CDEST_14987) |
| BFU: | BCIN_10g02880(Bcpos5) |
| PPSF: | 300794653(PFLUO_LOCUS8381) |
| PTRR: | 6338533(PtrM4_017020) |
| ADAC: | 96088833(ACET3X_008511) |
| CDEC: | 89987833(IAS62_001058) |
| CTEG: | 91989018(I308_102160) |
| CBAS: | 91982210(I312_102162) |
| CDEP: | 91089745(L203_105536) |
| KMG: | 30167539(I203_106451) |
| KNE: | 92178255(IAR55_000996) |
| KDJ: | 28964807(I303_101104) |
| KBI: | 30207323(I302_104215) |
| KPIN: | 30169368(I206_100326) |
| KSH: | 87953120(IL334_000989) |
| KER: | 91106249(V865_007448) |
| KSN: | 43588567(CI109_102412) |
| KEP: | 91091707(L201_001035) |
| CCAC: | CcaHIS019_0504090(POS5) |
| ABP: | AGABI1DRAFT99179(AGABI1DRAFT_99179) |
| ABV: | AGABI2DRAFT178464(AGABI2DRAFT_178464) |
| SCM: | SCHCO_02631517(SCHCODRAFT_02631517) |
| PGR: | PGTG_16175 PGTG_18830 |
| PTRC: | PtA15_4A524 PtA15_6A737 |
| PTM: | GSPATT00006279001 GSPATT00009606001 |
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| Reference |
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| Authors |
Griffiths MM, Bernofsky C. |
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| Title |
Purification and properties of reduced diphosphopyridine nucleotide kinase from yeast mitochondria. |
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| Journal |
J Biol Chem 247:1473-8 (1972) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.7.1.86 |
| ExPASy - ENZYME nomenclature database: | 2.7.1.86 |
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| LinkDB |
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