Entry
Name
archaetidylinositol phosphate synthase;
AIP synthase
Class
Transferases;
Transferring phosphorus-containing groups;
Transferases for other substituted phosphate groups
BRITE hierarchy
Sysname
CDP-2,3-bis-(O-phytanyl)-sn-glycerol:1L-myo-inositol 1-phosphate 1-sn-archaetidyltransferase
Reaction(IUBMB)
CDP-2,3-bis-(O-phytanyl)-sn-glycerol + 1L-myo-inositol 1-phosphate = CMP + 1-archaetidyl-1D-myo-inositol 3-phosphate [RN:
R10464 ]
Reaction(KEGG)
Substrate
CDP-2,3-bis-(O-phytanyl)-sn-glycerol [CPD:
C20627 ];
1L-myo-inositol 1-phosphate [CPD:
C04006 ]
Product
CMP [CPD:
C00055 ];
1-archaetidyl-1D-myo-inositol 3-phosphate [CPD:
C20642 ]
Comment
Requires Mg2+ or Mn2+ for activity. The enzyme is involved in biosynthesis of archaetidyl-myo-inositol, a compound essential for glycolipid biosynthesis in archaea.
History
EC 2.7.8.39 created 2013
Orthology
K17884 archaetidylinositol phosphate synthase
Genes
GPN : Pan110_16930(pgsA_1)
HYA : HY04AAS1_0066 HY04AAS1_1447
HHO : HydHO_0067 HydHO_1428
HYS : HydSN_0070 HydSN_1468
HTE : Hydth_1619 Hydth_1698
TRD : THERU_03025 THERU_08220
SAF : SULAZ_0080 SULAZ_1542
PMX : PERMA_0154 PERMA_0500
DTE : Dester_0086 Dester_0599
MRTJ : KHC33_00445 KHC33_09585
MEM : Memar_1397 Memar_1904
MBG : BN140_0481(pgsA3) BN140_1190(pgsA5)
MEMA : MMAB1_0596(pgsA) MMAB1_1510
MCHK : MchiMG62_15910 MchiMG62_22030
MSUM : OH143_01205 OH143_03775
MFO : Metfor_0706 Metfor_2281
HJT : DVR14_19175 DVR14_23305
TVO : TVG0612669(TVG0612669)
LOKI : Lokiarch_09020 Lokiarch_11020 Lokiarch_26630(pgsA1) Lokiarch_43440
PSYT : DSAG12_01829 DSAG12_02404 DSAG12_03628
» show all
Taxonomy
Reference
Authors
Morii H, Kiyonari S, Ishino Y, Koga Y
Title
A novel biosynthetic pathway of archaetidyl-myo-inositol via archaetidyl-myo-inositol phosphate from CDP-archaeol and D-glucose 6-phosphate in methanoarchaeon Methanothermobacter thermautotrophicus cells.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.7.8.39
ExPASy - ENZYME nomenclature database: 2.7.8.39
LinkDB
All DBs