Entry |
|
Name |
ADP-dependent short-chain-acyl-CoA hydrolase;
short-chain acyl coenzyme A hydrolase;
propionyl coenzyme A hydrolase;
propionyl-CoA hydrolase;
propionyl-CoA thioesterase;
short-chain acyl-CoA hydrolase;
short-chain acyl-CoA thioesterase
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Class |
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
|
Sysname |
ADP-dependent-short-chain-acyl-CoA hydrolase
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Reaction(IUBMB) |
acyl-CoA + H2O = CoA + a carboxylate [RN: R00383]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Requires ADP; inhibited by NADH. Maximum activity is shown with propanoyl-CoA.
|
History |
EC 3.1.2.18 created 1992
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Reference |
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Authors |
Alexson SE, Nedergaard J. |
Title |
A novel type of short- and medium-chain acyl-CoA hydrolases in brown adipose tissue mitochondria. |
Journal |
J Biol Chem 263:13564-71 (1988) |
Reference |
|
Authors |
Alexson SE, Svensson LT, Nedergaard J. |
Title |
NADH-sensitive propionyl-CoA hydrolase in brown-adipose-tissue mitochondria of the rat. |
Journal |
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Other DBs |
ExplorEnz - The Enzyme Database: | 3.1.2.18 |
ExPASy - ENZYME nomenclature database: | 3.1.2.18 |
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LinkDB |
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