Entry
Name
deacetylisoipecoside synthase;
deacetylisoipecoside dopamine-lyase;
deacetylisoipecoside dopamine-lyase (secologanin-forming)
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In other compounds
BRITE hierarchy
Sysname
deacetylisoipecoside dopamine-hydolase (secologanin-forming)
Reaction(IUBMB)
deacetylisoipecoside + H2O = dopamine + secologanin [RN:
R05750 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme from the leaves of Alangium lamarckii differs in enantiomeric specificity from EC
3.5.99.16 , deacetylipecoside synthase. The product is rapidly converted to demethylisoalangiside.
History
EC 3.5.99.15 created 2000 as EC 4.3.3.3, transferred 2024 to EC 3.5.99.15
Pathway
ec00950 Isoquinoline alkaloid biosynthesis
ec01110 Biosynthesis of secondary metabolites
Reference
1
Authors
DeEknamkul, W., Ounaroon, A., Tanahashi, T., Kutchan, T. and Zenk, M.H.
Title
Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii.
Journal
Phytochemistry 45:477-484 (1997)
Other DBs
ExPASy - ENZYME nomenclature database: 3.5.99.15
LinkDB
All DBs