KEGG ENZYME: 4.1.1.121

ENZYME: 4.1.1.121

Entry

EC 4.1.1.121                Enzyme

Name

3-oxoisoapionate-4-phosphate decarboxylase;
oiaX (gene name)

Class

Lyases;
Carbon-carbon lyases;
Carboxy-lyases

Sysname

3-oxoisoapionate 4-phosphate carboxy-lyase

Reaction(IUBMB)

3-oxoisoapionate 4-phosphate = L-erythrulose 1-phosphate + CO2 [RN:R12610]

Reaction(KEGG)

R12610

Substrate

3-oxoisoapionate 4-phosphate [CPD:C22278]

Product

L-erythrulose 1-phosphate [CPD:C03394];
CO2 [CPD:C00011]

Comment

The enzyme, characterized from several bacterial species, participates in the degradation of D-apionate. It belongs to the RuBisCO-like-protein (RLP) superfamily. Stereospecificity of 3-oxoisoapionate 4-phosphate has not been determined.

History

EC 4.1.1.121 created 2020

Orthology

K24268

3-oxoisoapionate-4-phosphate decarboxylase

Genes

MMW:	Mmwyl1_3120

MME:	Marme_1595

MPRI:

MP3633_1135

MARD:

IBG28_06425

MLO:

mll7006

MLN:	A9174_13135

MCI:	Mesci_5314

MCIC:

A4R28_00540

MOP:	Mesop_5775

MAM:	Mesau_05270

MAMO:

A6B35_09510

MESW:

A9K65_029050

MESM:

EJ066_15505

MHUA:

MCHK_0231

MJR:	EB229_13270

MERD:

EB233_28475

MOH:	IHQ72_30660

MMEI:

LRP31_29990

SME:	SM_b20393(rbcL)

SMK:	Sinme_3785

SMQ:	SinmeB_4281

SMX:	SM11_pD1220(rbcL)

SMI:	BN406_06279

SMEG:

C770_GR4pD1209

SMEL:

SM2011_b20393(rbcL)

SMER:

DU99_31335

SMD:

Smed_3724

RHI:	NGR_b22000(rbcL1) NGR_c06470(rbcL2)

SFH:	SFHH103_05031(rbcL)

SFD:	USDA257_c23120

SIX:	BSY16_3626

SAME:

SAMCFNEI73_pC0434(rbcL)

SINO:

SS05631_b62680

ENU:	PYH37_000278

SKM:	PZL22_001157

EAD:	OV14_b0206(rbcL1)

ECAA:

J3R84_34875

ASAL:

CFBP5507_25125

RET:	RHE_PF00042(rbcL)

REC:	RHECIAT_PC0000964(rbcL)

REL:	REMIM1_PF00046

REI:	IE4771_PA00099

RLE:	pRL120396(cbbl1)

RLT:	Rleg2_4649

RLG:

Rleg_4762

RLB:	RLEG3_07495

RTR:	RTCIAT899_PC04845

RHL:	LPU83_pLPU83c0539(rbcL)

RGA:	RGR602_PA00082 RGR602_PC01940

RHN:	AMJ98_PE00045

RPHA:

AMC79_PD00971

RHX:	AMK02_PD00048

REZ:	AMJ99_PD00045

RJG:	CCGE525_32340

RHR:	CKA34_20615

RGR:	FZ934_27725

RAD:	CO657_24185 CO657_28385

RII:	FFM53_024620

RBAN:

J2J98_22025

RRG:	J3P73_25285

RLS:	HB780_06780

RAW:	NE851_33225

RSUL:

N2599_21485

RLW:	RlegWSM1455_25760

RRHO:

PR018_17285

RTU:	PR017_17170

ARA:	Arad_9230(rbcL)

RBW:	RLCC275e_25230

SHZ:

shn_27395

SZO:	K8M09_21805

SOJ:	K6301_18775

SSUM:

Q9314_21130

OIN:	IAR37_15445

OAN:

Oant_3067

OAH:

DR92_3436

OPS:	A8A54_12360

BPSN:

NIK97_14660

OCH:	CES85_5837

OCR:	HGK82_18460

OCL:	GTN27_19405

LNE:	FZC33_05815

MMED:

Mame_04753(rlp2)

AUA:	M673_08880

AALA:

IGS74_19135

AALM:

LUX29_21325

LIZ:	LGH83_09605

CMAR:

IMCC12053_1019

TPRO:

Ga0080559_TMP304

MALU:

KU6B_32220

PALX:

GQA70_00810

PARR:

EOJ32_13855

PLIA:

E4191_04050 E4191_17675

PMAU:

CP157_00833(rlp2)

PSAP:

JHX88_15345

TEC:	AKL02_017845

GOY:	GLS_c05850

LCK:	HN018_21595

NFS:	OIE67_32790

ATEE:

K9M52_06930

SAWL:

NGM29_18835

» show all

Reference

1 [PMID:29867142]

Authors

Carter MS, Zhang X, Huang H, Bouvier JT, Francisco BS, Vetting MW, Al-Obaidi N, Bonanno JB, Ghosh A, Zallot RG, Andersen HM, Almo SC, Gerlt JA

Title

Functional assignment of multiple catabolic pathways for D-apiose.

Journal

Nat Chem Biol 14:696-705 (2018)
DOI:10.1038/s41589-018-0067-7

Sequence

[ara:Arad_9230] [ret:RHE_PF00042]

Other DBs

ExplorEnz - The Enzyme Database:

4.1.1.121

IUBMB Enzyme Nomenclature:

4.1.1.121

ExPASy - ENZYME nomenclature database:

4.1.1.121

BRENDA, the Enzyme Database:

4.1.1.121

LinkDB

DBGET integrated database retrieval system