Entry
Name
anhydromevalonate phosphate decarboxylase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
trans-anhydromevalonate 5-phosphate carboxy-lyase
Reaction(IUBMB)
trans-anhydromevalonate 5-phosphate = 3-methylbut-3-en-1-yl phosphate + CO2 [RN:
R12895 ]
Reaction(KEGG)
Substrate
trans-anhydromevalonate 5-phosphate [CPD:
C22453 ]
Product
3-methylbut-3-en-1-yl phosphate [CPD:
C20345 ];
CO2 [CPD:
C00011 ]
Comment
The enzyme catalyses a step in the archaeal prenyl diphosphate biosynthesis pathway. It requires a prenylated flavin cofactor that is produced by EC
2.5.1.129 , flavin prenyltransferase.
History
EC 4.1.1.126 created 2023
Pathway
ec00900 Terpenoid backbone biosynthesis
ec01110 Biosynthesis of secondary metabolites
Orthology
K25518 anhydromevalonate phosphate decarboxylase
Genes
LOKI : Lokiarch_22670(ubiD)
» show all
Taxonomy
Reference
Authors
Yoshida R, Yoshimura T, Hemmi H.
Title
Reconstruction of the "Archaeal" Mevalonate Pathway from the Methanogenic Archaeon Methanosarcina mazei in Escherichia coli Cells.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 4.1.1.126
LinkDB
All DBs