KEGG ENZYME: 4.1.2.28

ENZYME: 4.1.2.28

Entry

EC 4.1.2.28                 Enzyme

Name

2-dehydro-3-deoxy-D-pentonate aldolase;
2-keto-3-deoxy-D-pentonate aldolase;
3-deoxy-D-pentulosonic acid aldolase;
2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase

Class

Lyases;
Carbon-carbon lyases;
Aldehyde-lyases

Sysname

2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase (pyruvate-forming)

Reaction(IUBMB)

2-dehydro-3-deoxy-D-pentonate = pyruvate + glycolaldehyde [RN:R01782]

Reaction(KEGG)

R01782

Substrate

2-dehydro-3-deoxy-D-pentonate [CPD:C03826]

Product

pyruvate [CPD:C00022];
glycolaldehyde [CPD:C00266]

History

EC 4.1.2.28 created 1976

Pathway

ec00040

Pentose and glucuronate interconversions

ec01100

Metabolic pathways

Orthology

K22397

2-dehydro-3-deoxy-D-pentonate aldolase

Genes

ECO:	b0268(yagE) b4298(yjhH)

ECJ:	JW0261(yagE) JW5775(yjhH)

ECD:	ECDH10B_0255(yagE) ECDH10B_4499(yjhH)

EBW:	BWG_3995(yjhH)

ECOC:

C3026_01300 C3026_23190

EUN:	UMNK88_5121

ENA:	ECNA114_4329 ECNA114_4493

ECOS:

EC958_0021 EC958_4764

ECOA:

APECO78_02600

EUM:	ECUMN_4897(yjhH)

ECZ:	ECS88_4909(yjhH)

ELO:	EC042_4655

ESE:

ECSF_4230

EDH:	EcDH1_3337 EcDH1_3702

EDJ:	ECDH1ME8569_0256(yagE) ECDH1ME8569_4155(yjhH)

ELP:	P12B_c4277(dapA)

ECOJ:

P423_23770 P423_24415 P423_26105

EMA:	C1192_17755

ESZ:	FEM44_11215

ERUY:

OSH18_13850

STM:

STM3532

SEO:	STM14_4252

SEV:	STMMW_35211

SEY:	SL1344_3499

SEM:	STMDT12_C35870 STMDT12_C38810

SEJ:	STMUK_3517

SEB:	STM474_3699

SEF:	UMN798_3835

SETU:

STU288_17850

SETC:

CFSAN001921_22785

SENR:

STMDT2_34191

SEND:

DT104_35151

SENI:

CY43_18350

SEEN:

SE451236_03250

SPQ:	SPAB_04387

SEI:

SPC_3601

SEC:	SCH_3462(yagE)

SEH:	SeHA_C3841

SHB:

SU5_04007

SENH:

CFSAN002069_14520

SEEH:

SEEH1578_03740

SEE:	SNSL254_A3799

SENN:

SN31241_3610

SEA:	SeAg_B3733

SENS:

Q786_17235

SED:

SeD_A3902

SEG:

SG3907

SEL:

SPUL_4048

SEGA:

SPUCDC_4034

SET:

SEN3356

SENA:

AU38_17125

SENO:

AU37_17315

SENV:

AU39_17320

SENQ:

AU40_19290

SENL:

IY59_17750

SEEC:

CFSAN002050_24615

SEEB:

SEEB0189_002215

SEEP:

I137_19355

SENB:

BN855_36050

SENE:

IA1_17125

SENC:

SEET0819_01250

SHIG:

LXH19_19890

ENC:

ECL_00673

ENL:	A3UG_02635

ECLG:

EC036_04970

ECLE:

ECNIH2_03525

ECLN:

ECNIH4_20265

ECLI:

ECNIH5_02700

ECLX:

LI66_02540

ECLY:

LI62_03025

ECLZ:

LI64_02720

ECLO:

ENC_43800

EHM:	AB284_22495

EXF:	BFV63_02530

ECLA:

ECNIH3_02700

ECLC:

ECR091_02690

EAU:	DI57_16045

EKB:	BFV64_02250

ENO:	ECENHK_02575

EEC:	EcWSU1_00475(yagE)

ELG:	BH714_17035

ECAN:

CWI88_19625

ERN:	BFV67_02475

ECLS:

LI67_003565

ESH:	C1N69_02555

EPT:	HWQ17_09945(yagE)

ECHU:

RQP59_02920(yagE)

ENT:	Ent638_0454

ENR:	H650_15575

ENF:	AKI40_4379(yjhH) AKI40_4872

LNI:	CWR52_09710

EBG:	FAI37_04040(yagE)

END:	A4308_00285

ENS:	HWQ15_11030(yagE)

ENK:	LOC22_13415(yagE)

EMOR:

L6Y89_02470(yagE)

ENB:	ELK40_03205

EQU:	OM418_02495(yagE)

EPU:	QVH39_02540(yagE)

EDY:	F0320_02380(yagE)

ENTE:

GXP72_02640(yagE)

ENTY:

H2Z33_05370(yagE)

ENJ:	QRD42_05320

ENTL:

FZF21_07400(yagE)

ENTJ:

RY075_03150(yagE)

KOX:

KOX_04820

KOE:

A225_5428

KOY:	J415_04940

KOM:	HR38_03390

KOK:	KONIH1_27340

KOC:	AB185_08945

KLL:	BJF97_27005

KLW:	DA718_01985 DA718_02105 DA718_14745 DA718_14865

KGR:	JJJ10_01715

KPAS:

LUW96_00315 LUW96_04845

KLC:	K7H21_01680 K7H21_06420

KLM:	BWI76_26315

REE:	electrica_00307(yagE_1) electrica_04108(yagE_2) electrica_04531(yagE_3)

KLP:	GUC22_01645

ROR:	RORB6_16145 RORB6_20365

RON:	TE10_04880

RPLN:

B1209_00195

RAO:	DSD31_01705 DSD31_22955

RTG:	NCTC13098_06010(yagE_1) NCTC13098_06573(yagE_2)

CRO:

ROD_38421

CKO:	CKO_03091 CKO_05139

CFD:	CFNIH1_06425 CFNIH1_07135

CBRA:

A6J81_16195 A6J81_25545

CWE:	CO701_21160

CYO:	CD187_10460 CD187_23175

CPOT:

FOB25_10450

CFQ:	C2U38_24980

CSED:

JY391_21515

CAMA:

F384_04750 F384_04805 F384_18625 F384_21250

CAF:	AL524_01290 AL524_04095 AL524_17455

CIF:	AL515_01100 AL515_02195

CFAR:

CI104_01575 CI104_09810 CI104_09900 CI104_24240

CIR:	C2U53_07840 C2U53_10825 C2U53_19645

CIE:	AN232_03445

CPAR:

CUC49_20145

CTEL:

GBC03_02790 GBC03_05480 GBC03_20370 GBC03_20495

CITZ:

E4Z61_16165

CARS:

E1B03_01925

CIX:	M4I31_00195 M4I31_23040

CIB:	HF677_022790

CENS:

P2W74_01355 P2W74_22410

CITR:

GUC46_22970

CIQ:	FD428_00225 FD428_20735

CIY:	HAP28_01800 HAP28_09745 HAP28_24230

ESC:	Entcl_4352

KLE:	AO703_00120

KSA:	C813_14970

KOR:	AWR26_25835

KRD:	A3780_25155

KCO:	BWI95_01085

KOT:	EH164_21940

KPSE:

IP581_00375

KOB:	HF650_23840

KOO:	O9K67_21595 O9K67_24080

KOU:	C0557_13530 C0557_26640

KCA:	AAEY27_21750

LAX:	APT61_19890

LEI:	C2U54_07345

LEH:	C3F35_09250

LEE:	DVA44_21305

LER:	GNG29_02705

LEA:	GNG26_02250

LPNU:

KQ929_18235

LEY:	DVA43_15285

LEF:	LJPFL01_0504

LEW:	DAI21_01695

BAGE:

BADSM9389_18520

SYM:	K6K13_20580

AHN:	NCTC12129_03315(yagE)

ASUB:

NLZ15_04835 NLZ15_07990 NLZ15_20465

YRE:	HEC60_18325

SGOE:

A8O29_022090

KIN:	AB182_24675 AB182_25650

PDZ:	HHA33_01720 HHA33_02595

METY:

MRY16398_00660(yjhH) MRY16398_55450(dapA)

SCOL:

KFZ77_00505

SUPE:

P0H77_00200 P0H77_19405 P0H77_22410

TOE:	QMG90_15705 QMG90_21610

MPHG:

MPHASIOC01_002172(dapA)

EBF:

D782_0032

EBC:	C2U52_07695 C2U52_08660

EBB:	F652_2136 F652_3732

YRO:

CH64_876

YAS:	N0H69_14410

SFW:	WN53_24685

SFG:	AV650_10505

SFO:	Z042_19360

RAH:	Rahaq_2409

RACE:

JHW33_04885

RAQ:	Rahaq2_2474

RAA:

Q7S_12200

ROX:	BV494_06660

RVC:	J9880_17695

RBAD:

H2866_16855

RCB:	O1V66_03795

ROU:	AB3G37_14460

CARU:

P0E69_08680

NIG:	C1N62_07340

SERA:

Ser39006_006395

SERQ:

CWC46_06390

PROD:

PCO85_19180

PWA:	Pecwa_3705

PPAR:

A8F97_00140

PEC:

W5S_3846

PWS:	A7983_03575

PCAC:

OI450_14695

BGJ:	AWC36_00370 AWC36_05705

BNG:	EH206_03805

SOD:	Sant_3778 Sant_3785

SLIG:

GTU79_18585

ETO:	RIN69_17620

PVA:	Pvag_2407(yagE)

PAGG:

AL522_19245

PAO:	Pat9b_3067

KLN:	LH22_07185

PANP:

PSNIH2_02525

PAGC:

BEE12_02705

PALH:

B1H58_11630

PANS:

FCN45_14855

PEY:	EE896_04370

PJI:	KTJ90_04260

KPIE:

N5580_03710

PALF:

K6R05_04305

PPHO:

CTZ24_13140

PANE:

P6287_15125

PAMT:

IAI47_04285

PANZ:

NR302_14835

PPHI:

ACF2G4_10260

PGZ:	C2E15_16705

PCD:	C2E16_16540

MINT:

C7M51_02515(yagE)

MTHI:

C7M52_00340(yagE)

MHAN:

K6958_16240

PRG:	RB151_012970(yagE)

PRQ:	CYG50_09510

PHAG:

PZ638_14365

PXH:	ACE2AL_14235

PROV:

ABE954_15365

MMK:

MU9_1638

LPV:	HYN51_02285 HYN51_02940

PRAG:

EKN56_09050 EKN56_10120

LRI:	NCTC12151_00916(yagE_1) NCTC12151_02133(yagE_2) NCTC12151_02810(yagE_3)

LGB:	V8L73_11395

VCK:	PG915_09940

EMO:	DM558_01555 DM558_10135

COV:	EKO29_03270

PBW:	D172_006755

GAG:	Glaag_2035

GAP:	GAPWK_2483

GAQ:	RAM11_02435

ORB:	IPMB12_09380

OMO:	RHO11_04085

OWH:	RHO14_05625

OSV:	RHO12_04135

UBR:	RHO15_01260

PEW:	KZJ38_34555

SUTK:

FG381_10605

RPC:

RPC_4382

DAG:	PSQ19_16215

MEY:	TM49_03325

RAGG:

QUB73_30455

SPCA:

GL174_14825

RAP:	RHOA_3606(yagE) RHOA_4577(yagE)

CFF:	CFF8240_1063

CFV:	CFVI03293_1018

CFX:	CFV97608_1117(dapA2)

CFZ:

CSG_9320

CAMP:

CFT03427_1043(dapA2)

CFP:	CR44_05305

CGEO:

CGEO_0772

ANT:	Arnit_0013

AIE:	LXN10_06755

PMEN:

V8V93_07460

BWS:	WCP94_004476

TNR:	Thena_0868

TACI:

TDSAC_0988

SNG:	SNE_A15450(dapA-B)

VBH:	CMV30_05070

SLOM:

PXH66_13795

OBT:	OPIT5_25740

ROO:	G5S37_13650

VBA:	IMCC26134_04565

RBA:	RB8798(dapA)

RUL:	UC8_48010(dapA_3)

ROL:	CA51_39430(yagE_2) CA51_44160(dapA_5) CA51_49760(yagE_4)

RUV:	EC9_50700(yagE_4)

RCF:	Poly24_50140(yagE_3)

AHEL:

Q31a_61470(dapA_4)

LCRE:

Pla8534_54150(yagE_1)

AAGG:

ETAA8_27310(yagE_2)

BVO:	Pan97_09440(dapA_1) Pan97_26400(yagE)

TTF:

THTE_2499

LPAV:

PLANPX_0768

PBS:	Plabr_4231 Plabr_4353

PLS:	VT03_03445(yagE)

GMR:	GmarT_12480(yagE)

SDYN:

Mal52_61950(yagE)

PLON:

Pla110_37180(yagE)

SVP:	Pan189_33060(yagE)

LRS:	PX52LOC_00995(dapA_1)

FTJ:

FTUN_2672

ULI:	ETAA1_47670(dapA_2)

KNV:	Pan216_01840(yagE_1)

PHM:	PSMK_11540

PCOR:

KS4_01010(dapA_1)

PBU:	L21SP3_01493(yagE)

PBP:	STSP1_01490(yagE)

BVU:

BVU_2788

BDO:	EL88_07320

BDH:	GV66_15245

PMUC:

ING2E5A_0522(dapA_1)

PET:	PEIBARAKI_6813

PSAC:

PSM36_0023

MCOS:

GM418_26075

FLS:	GLV81_12725

PSN:	Pedsa_0328

SHG:	Sph21_0982

MRUB:

DEO27_002315

MGOS:

DIU38_017895

MMAB:

HQ865_16915

OLI:	FKG96_01910

CMR:	Cycma_0383

CAMU:

CA2015_0287

EVI:	Echvi_1276 Echvi_4516

EST:	DN752_01100 DN752_12410

ECHI:

FKX85_03990

ALM:	AO498_15705

SPIK:

EXU85_19355

SPIB:

G8759_13710

ALS:	DJ013_02060

ADD:	HUW48_09365

MART:

BTR34_16285

POB:	LPB03_10430

AALG:

AREALGSMS7_00142 AREALGSMS7_01293

MARF:

CJ739_1032 CJ739_2281

EMAR:

D1013_15070

BCO:	Bcell_3740

BCIR:

C2I06_01710

NTX:	NQZ71_16650

NIL:	L8T27_005325

NTGC:

AB3U99_08070

BMEG:

BG04_4041

BEO:

BEH_10570

PRIE:

ACN5XJ_17860

BCL:

ABC1113

CFIR:

NAF01_22345

OCN:	CUC15_04735

LYP:	MTP04_27730(dapA1)

HNZ:	P9989_17300

HSAN:

MUN89_20960

VIG:	BKP57_15530

VPT:	KBP50_14380

VIK:	KFZ58_05945

BMUR:

ABE28_018945

PBUT:

DTO10_00785

PFRI:

L8956_13680

PERI:

RE409_16030

PERJ:

JNUCC41_23010

PERS:

ACJ9PY_13755

SCIB:

HUG20_02235

NMK:	CHR53_12345

NDT:	L1999_26485

MSEM:

GMB29_13550

CTHU:

HUR95_16410

PSUA:

FLK61_39625

DOM:	RRU94_04330

BBAM:

RJD24_17835

FEC:	QNH15_13085

GKA:

GK1961

GTM:	GT3921_09745

GTN:

GTNG_1861

GCT:	GC56T3_1553

GJF:	M493_10115

GEL:	IB49_01615

GEJ:	A0V43_07445

PARG:

PspKH34_22130(yjhH)

PCAL:

BV455_03532(yagE_2)

SKL:	C7J89_02195(dapA)

SLLO:

ISP08_01045(dapA)

PBD:	PBOR_25515

PGM:	PGRAT_22535

PAEN:

P40081_25605

PAEQ:

R50912_23705

PRI:	PRIO_4858(yagE)

PSON:

JI735_31980

PCX:	LPB68_01015

PTRI:

KDC22_22405

PTJ:	JRJ22_13285

PTHI:

NDS46_11455

PDY:	QJQ58_10685

PHC:	BBI08_12060

PMAR:

B0X71_14405

SPSY:

AZE41_19030

SURE:

SporoP32a_11190

LKL:	DKL58_08725

LBM:	DS830_06180

CBE:

Cbei_4128

CBZ:

Cbs_4128

CLJ:	CLJU_c00600 CLJU_c28230

CSR:	Cspa_c22380(yagE)

CPAS:

Clopa_0817

CAH:	CAETHG_0823 CAETHG_2178 CAETHG_2398

CSQ:

CSCA_4464

CDRK:

B9W14_22675

CDY:	F3K33_21115

CLOS:

DMR38_00190 DMR38_14115 DMR38_14350

CLOM:

AXY43_08790

CCE:

Ccel_1265

RPAY:

P0092_05435

OBJ:	EIO64_14630

CAPR:

EQM14_10080

CFEM:

HCR03_13070

CCOM:

I6K69_07865

BYL:	A4V09_21855

BPRO:

PMF13cell1_01054(yagE)

BCOC:

BLCOC_50100(yjhH)

BLAR:

LC508_22135

HHJ:	NQ487_23180

CACE:

CACET_c14830

CFM:	BJL90_19970 BJL90_20335

GFE:	Gferi_06675

CDF:	CD630_30000(dapA1)

PDC:	CDIF630_03285(dapA1)

CDC:	CD196_2789

CDL:	CDR20291_2836

PDF:	CD630DERM_30000(dapA1)

TWI:	Thewi_1727

CHY:	CHY_1320(dapA2)

GEK:	kuro4_24770

MAS:	Mahau_1779

PEQU:

O6R05_07610

AMEI:

LV469_02710

MHW:	ACT01_13565

MEG:	DKB62_02780

SELO:

AXE86_07090

SELT:

BCS37_10060

SELM:

TAMA11512_23380

STIM:

H1B31_03995

STED:

SPTER_02970(yagE)

SSPH:

SPSPH_005570(yagE)

SOVA:

SOV_06310(yagE)

SSID:

SPSIL_007160(yagE)

SACV:

SPACI_001600(yjhH_1) SPACI_007610(yagE_1)

PCAT:

Pcatena_05920(dapA_3)

ATB:	J4859_04885

LCAL:

ATTO_12950(dapA)

MCHT:

MCHIJ_27770

CII:	CIMIT_11875

CSTA:

CSTAT_07550

CAMG:

CAMM_07780

CPRP:

I6I69_03115

CGLU:

I6J20_09355

CPSP:

L9H27_08355

NBR:	O3I_024355

NWL:	NWFMUON74_17580(dapA_1)

NHU:	H0264_11500

NGP:	LTT66_21690

NSPU:

IFM12276_40910(dapA_3)

NVU:	V7968_32330

AUL:	DCC27_010590

AIG:	QDX25_10570

CIRA:

LFM56_16175

CELC:

K5O09_03300

CELE:

P9841_07310

ANW:	QP939_41300

AWL:	P8A24_00430

ACAS:

P7079_00275

ASG:	FB03_06935

AUU:	CJ184_005300

ATIM:

CYJ17_0002600 CYJ17_0007940

ACTT:

DDD63_11265

BLN:

Blon_2338

BLON:

BLIJ_2415

BLL:	BLJ_0324 BLJ_1832

BLX:	GS08_01705 GS08_09510

BBV:	HMPREF9228_0579 HMPREF9228_1819

BBRU:

Bbr_1289(dapA3) Bbr_1740(dapA4)

BBRE:

B12L_1235 B12L_1670

BBRV:

B689b_1318 B689b_1768

BBRJ:

B7017_1260 B7017_1934

BBRC:

B7019_1471 B7019_1906

BBRN:

B2258_1265 B2258_1760

BBRS:

BS27_1312(dapA3) BS27_1733(dapA4)

BBRD:

BBBR_1350 BBBR_1741

BKA:	AH68_10225

BKS:

BBKW_1834

BPSC:

BBPC_1771

BSCA:

BBSC_0459

BACT:

AB656_00400 AB656_04235

GVG:	HMPREF0421_20691

GVH:	HMPREF9231_0874

GPT:	K9E43_05735

FVA:	FV113G1_00910

FUL:	C4N20_05820

FMO:	C4N19_05855

ACJ:	ACAM_0671(dapA)

VDI:

Vdis_2525

VMO:

VMUT_0870

» show all

Reference

1 [PMID:4423285]

Authors

Dahms AS.

Title

3-Deoxy-D-pentulosonic acid aldolase and its role in a new pathway of D-xylose degradation.

Journal

Biochem Biophys Res Commun 60:1433-9 (1974)
DOI:10.1016/0006-291X(74)90358-1

Reference

2 [PMID:7154955]

Authors

Dahms AS, Donald A.

Title

2-Keto-3-deoxy-d-xylonate aldolase (3-deoxy-d-pentulosonic acid aldolase).

Journal

Methods Enzymol 90 Pt E:269-72 (1982)
DOI:10.1016/s0076-6879(82)90138-0

Other DBs

ExplorEnz - The Enzyme Database:

4.1.2.28

IUBMB Enzyme Nomenclature:

4.1.2.28

ExPASy - ENZYME nomenclature database:

4.1.2.28

BRENDA, the Enzyme Database:

4.1.2.28

CAS:	55326-36-8

LinkDB

DBGET integrated database retrieval system