Entry
Name
(3S)-(+)-asterisca-2(9),6-diene synthase;
TPS2 (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (3S)-(+)-asterisca-2(9),6-diene-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (3S)-(+)-asterisca-2(9),6-diene + diphosphate [RN:
R11826 ]
Reaction(KEGG)
Substrate
(2E,6E)-farnesyl diphosphate [CPD:
C00448 ]
Product
(3S)-(+)-asterisca-2(9),6-diene [CPD:
C21677 ];
diphosphate [CPD:
C00013 ]
Comment
The sequiterpene (3S)-(+)-asterisca-2(9),6-diene has been shown to be synthezised in the slime-mould Dictyostelium discoideum. The enzyme is specific for (2E,6E)-farnesyl diphosphate.
History
EC 4.2.3.161 created 2017
Orthology
K23022 (3S)-(+)-asterisca-2(9),6-diene synthase
Genes
Taxonomy
Reference
Authors
Chen X, Kollner TG, Jia Q, Norris A, Santhanam B, Rabe P, Dickschat JS, Shaulsky G, Gershenzon J, Chen F
Title
Terpene synthase genes in eukaryotes beyond plants and fungi: Occurrence in social amoebae.
Journal
Reference
Authors
Rabe P, Rinkel J, Nubbemeyer B, Kollner TG, Chen F, Dickschat JS
Title
Terpene Cyclases from Social Amoebae.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 4.2.3.161
LinkDB
All DBs