ENZYME: 4.2.3.45
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Entry
EC 4.2.3.45 Enzyme
Name
phyllocladan-16alpha-ol synthase;
PaDC1
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(+)-copalyl-diphosphate diphosphate-lyase (phyllocladan-16alpha-ol-forming)
Reaction(IUBMB)
(+)-copalyl diphosphate + H2O = phyllocladan-16alpha-ol + diphosphate [RN:
R09686
]
Reaction(KEGG)
R09686
Reaction
Substrate
(+)-copalyl diphosphate [CPD:
C11901
];
H2O [CPD:
C00001
]
Product
phyllocladan-16alpha-ol [CPD:
C19817
];
diphosphate [CPD:
C00013
]
Comment
The adjacent gene PaDC2 codes EC
5.5.1.12
copalyl diphosphate synthase.
History
EC 4.2.3.45 created 2009
Pathway
ec00904
Diterpenoid biosynthesis
ec01110
Biosynthesis of secondary metabolites
Orthology
K20514
phyllocladan-16alpha-ol/copalyl diphosphate synthase
Reference
1 [PMID:
18391465
]
Authors
Toyomasu T, Niida R, Kenmoku H, Kanno Y, Miura S, Nakano C, Shiono Y, Mitsuhashi W, Toshima H, Oikawa H, Hoshino T, Dairi T, Kato N, Sassa T
Title
Identification of diterpene biosynthetic gene clusters and functional analysis of labdane-related diterpene cyclases in Phomopsis amygdali.
Journal
Biosci Biotechnol Biochem 72:1038-47 (2008)
DOI:
10.1271/bbb.70790
Sequence
[ag:
BAG30961
]
Other DBs
ExplorEnz - The Enzyme Database:
4.2.3.45
IUBMB Enzyme Nomenclature:
4.2.3.45
ExPASy - ENZYME nomenclature database:
4.2.3.45
BRENDA, the Enzyme Database:
4.2.3.45
LinkDB
All DBs
DBGET
integrated database retrieval system