KEGG   COMPOUND: C07013
Entry
C07013                      Compound                               
Name
Flurbiprofen
Formula
C15H13FO2
Exact mass
244.09
Mol weight
244.2609
Structure
Remark
Same as: D00330
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
   M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
    M01AE Propionic acid derivatives
     M01AE09 Flurbiprofen
      D00330  Flurbiprofen (JP18/USP/INN) <JP/US>
  M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
   M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
    M02AA Antiinflammatory preparations, non-steroids for topical use
     M02AA19 Flurbiprofen
      D00330  Flurbiprofen (JP18/USP/INN) <JP/US>
 R RESPIRATORY SYSTEM
  R02 THROAT PREPARATIONS
   R02A THROAT PREPARATIONS
    R02AX Other throat preparations
     R02AX01 Flurbiprofen
      D00330  Flurbiprofen (JP18/USP/INN) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BC Antiinflammatory agents, non-steroids
     S01BC04 Flurbiprofen
      D00330  Flurbiprofen (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Analgesics
  Nonsteroidal Anti-inflammatory Drugs
   Flurbiprofen
    D00330  Flurbiprofen (JP18/USP/INN)
 Ophthalmic Agents
  Ophthalmic Anti-inflammatories
   Nonsteroidal Anti-Inflammatory Drugs, Ophthalmic
    Flurbiprofen
     D00330  Flurbiprofen (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   114  Antipyretics and analgesics, anti-inflammatory agents
    1149  Others
     D00330  Flurbiprofen (JP18/USP/INN)
 2  Agents affecting individual organs
  26  Epidermides
   264  Analgesics, anti-itchings, astringents, anti-inflammatory agents
    2649  Others
     D00330  Flurbiprofen (JP18/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Drugs requiring guidance
  New approved switch OTC drugs
   Flurbiprofen
    D00330  Flurbiprofen (JP18/USP/INN)
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01504  Nonsteroidal anti-inflammatory drug (NSAID)
   DG01908  Anti-inflammatory drug, propionic acid derivatives
    DG00755  Flurbiprofen
     D00330  Flurbiprofen
 Metabolizing enzyme substrate
  DG01642  CYP2C9 substrate
   DG00755  Flurbiprofen
    D00330  Flurbiprofen
Drug classes [BR:br08332]
 Anti-inflammatory
  DG01504  Nonsteroidal anti-inflammatory drug (NSAID)
   D00330  Flurbiprofen
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Prostaglandin synthase
    PTGS1 (COX1)
     D00330  Flurbiprofen (JP18/USP/INN) <JP/US>
    PTGS2 (COX2)
     D00330  Flurbiprofen (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00330  Flurbiprofen
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D00330
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D00330
Prodrugs [br08324.html]
 D00330
Prodrugs [br08324.html]
 C07013
Other DBs
CAS: 5104-49-4
PubChem: 9226
LinkDB
KCF data

ATOM        18
            1   C8x C    28.9100  -18.0600
            2   C8y C    28.9100  -16.6600
            3   C8x C    27.6500  -15.9600
            4   C8x C    26.4600  -16.6600
            5   C8x C    26.4600  -18.0600
            6   C8x C    27.6500  -18.7600
            7   C8y C    30.1000  -15.9600
            8   C8y C    31.2900  -16.6600
            9   C8x C    32.5500  -15.9600
            10  C8y C    32.5500  -14.5600
            11  C8x C    31.2900  -13.8600
            12  C8x C    30.1000  -14.5600
            13  X   F    31.2900  -18.0600
            14  C1c C    33.7400  -13.8600
            15  C6a C    34.9300  -14.5600
            16  C1a C    33.7400  -12.5300
            17  O6a O    34.9300  -15.9600
            18  O6a O    36.1900  -13.8600
BOND        19
            1     4   5 2
            2     5   6 1
            3     7   8 2
            4     8   9 1
            5     9  10 2
            6    10  11 1
            7    11  12 2
            8    12   7 1
            9     6   1 2
            10    8  13 1
            11   10  14 1
            12    2   7 1
            13   14  15 1
            14    1   2 1
            15   14  16 1
            16    2   3 2
            17   15  17 2
            18    3   4 1
            19   15  18 1

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