| Entry |
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| Name |
Diclofenac potassium (USP);
Cambia (TN);
Cataflam (TN);
Zipsor (TN) |
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| Product |
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| Generic |
DICLOFENAC POTASSIUM (A-S Medication Solutions), DICLOFENAC POTASSIUM (A-S Medication Solutions), DICLOFENAC POTASSIUM (Advagen Pharma), DICLOFENAC POTASSIUM (Amici Pharmaceuticals LLC), DICLOFENAC POTASSIUM (Amici Pharmaceuticals LLC.), DICLOFENAC POTASSIUM (Archis Pharma LLC), DICLOFENAC POTASSIUM (Ascend Laboratories), DICLOFENAC POTASSIUM (Aurobindo Pharma Limited), DICLOFENAC POTASSIUM (Bryant Ranch Prepack), DICLOFENAC POTASSIUM (Bryant Ranch Prepack), DICLOFENAC POTASSIUM (Bryant Ranch Prepack), DICLOFENAC POTASSIUM (CARWIN PHARMACEUTICAL ASSOCIATES), DICLOFENAC POTASSIUM (Camber Pharmaceuticals), DICLOFENAC POTASSIUM (Chartwell RX), DICLOFENAC POTASSIUM (Cintex Services), DICLOFENAC POTASSIUM (Golden State Medical Supply), DICLOFENAC POTASSIUM (Havix Group Inc d-b-a Aavis Pharmaceuticals), DICLOFENAC POTASSIUM (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), DICLOFENAC POTASSIUM (INA Pharmaceutics), DICLOFENAC POTASSIUM (INA Pharmaceutics), DICLOFENAC POTASSIUM (Ingenus Pharmaceuticals), DICLOFENAC POTASSIUM (Lake Erie Medical DBA Quality Care Products LLC), DICLOFENAC POTASSIUM (Leading Pharma), DICLOFENAC POTASSIUM (Leading Pharma), DICLOFENAC POTASSIUM (Northwind Pharmaceuticals), DICLOFENAC POTASSIUM (NuCare Pharmaceuticals), DICLOFENAC POTASSIUM (NuCare Pharmaceuticals), DICLOFENAC POTASSIUM (NuCare Pharmaceuticals), DICLOFENAC POTASSIUM (PD-Rx Pharmaceuticals), DICLOFENAC POTASSIUM (Par Pharmaceutical), DICLOFENAC POTASSIUM (Proficient Rx LP), DICLOFENAC POTASSIUM (Quality Care Products), DICLOFENAC POTASSIUM (REMEDYREPACK), DICLOFENAC POTASSIUM (REMEDYREPACK), DICLOFENAC POTASSIUM (RPK Pharmaceuticals), DICLOFENAC POTASSIUM (Strides Pharma Science Limited), DICLOFENAC POTASSIUM (TEVA PHARMACEUTICALS), DICLOFENAC POTASSIUM (Teva Pharmaceuticals USA), DICLOFENAC POTASSIUM (Trifluent Pharma LLC), DICLOFENAC POTASSIUM (Trifluent Pharma LLC), DICLOFENAC POTASSIUM (UMEDICA LABORATORIES PRIVATE LIMITED), DICLOFENAC POTASSIUM (Zydus Pharmaceuticals (USA)), LOFENA (CARWIN PHARMACEUTICAL ASSOCIATES) |
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| Formula |
C14H10Cl2NO2. K
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| Exact mass |
332.9726
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| Mol weight |
334.239
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| Structure |
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| Simcomp |
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| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG01898 Anti-inflammatory drug, phenylacetic acid derivatives
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
Transporter inhibitor
DG02866 SLC22A8 inhibitor
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| Remark |
| Product (DG00441): | D00903<US> D00904<JP/US> D07818<US> |
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| Efficacy |
Anti-inflammatory, COX inhibitor |
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| Target |
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| Pathway |
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| Metabolism |
Enzyme: CYP2C9 [HSA: 1559]
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| Interaction |
Transporter inhibition: SLC22A8 [HSA: 9376]
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D11 OTHER DERMATOLOGICAL PREPARATIONS
D11A OTHER DERMATOLOGICAL PREPARATIONS
D11AX Other dermatologicals
D11AX18 Diclofenac
D00903 Diclofenac potassium (USP) <US>
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AB Acetic acid derivatives and related substances
M01AB05 Diclofenac
D00903 Diclofenac potassium (USP) <US>
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA15 Diclofenac
D00903 Diclofenac potassium (USP) <US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BC Antiinflammatory agents, non-steroids
S01BC03 Diclofenac
D00903 Diclofenac potassium (USP) <US>
USP drug classification [BR:br08302]
Analgesics
Nonsteroidal Anti-inflammatory Drugs
Diclofenac
D00903 Diclofenac potassium (USP)
Dermatological Agents
Dermatological Agents, Other
Warts and Actinic Keratosis Agents
Diclofenac
D00903 Diclofenac potassium (USP)
Ophthalmic Agents
Ophthalmic Anti-inflammatories
Nonsteroidal Anti-Inflammatory Drugs, Ophthalmic
Diclofenac
D00903 Diclofenac potassium (USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG01898 Anti-inflammatory drug, phenylacetic acid derivatives
DG00441 Diclofenac
D00903 Diclofenac potassium
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
DG00441 Diclofenac
D00903 Diclofenac potassium
Transporter inhibitor
DG02866 SLC22A8 inhibitor
DG00441 Diclofenac
D00903 Diclofenac potassium
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D00903 Diclofenac potassium
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D00903 Diclofenac potassium (USP) <US>
PTGS2 (COX2)
D00903 Diclofenac potassium (USP) <US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00903
Drug transporters
D00903
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG01898 Anti-inflammatory drug, phenylacetic acid derivatives
DG00441 Diclofenac
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
DG00441 Diclofenac
Transporter inhibitor
DG02866 SLC22A8 inhibitor
DG00441 Diclofenac
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 20
1 Z K 45.1317 -36.4561 #+
2 C8x C 37.3100 -37.1000
3 C8x C 37.3100 -38.5000
4 C8x C 38.5224 -39.2000
5 C8x C 39.7349 -38.5000
6 C8y C 39.7349 -37.1000
7 C8y C 38.5224 -36.4000
8 C1b C 40.9660 -36.3890
9 C6a C 42.1712 -37.0847
10 O6a O 43.3535 -36.4019 #-
11 O6a O 42.1716 -38.4996
12 N1b N 38.5224 -35.0002
13 C8y C 37.2932 -34.2903
14 C8y C 37.2935 -32.9001
15 C8x C 36.0812 -32.1999
16 C8x C 34.8686 -32.8996
17 C8x C 34.8683 -34.2898
18 C8y C 36.0806 -34.9901
19 X Cl 38.5184 -32.1931
20 X Cl 36.0806 -36.3997
BOND 20
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 6 8 1
8 8 9 1
9 9 10 1
10 9 11 2
11 7 12 1
12 12 13 1
13 13 14 2
14 14 15 1
15 15 16 2
16 16 17 1
17 17 18 2
18 13 18 1
19 14 19 1
20 18 20 1
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