| Entry |
|
|---|
| Name |
Bupranolol hydrochloride (JP18) |
|---|
| Formula |
C14H22ClNO2. HCl
|
|---|
| Exact mass |
307.1106
|
|---|
| Mol weight |
308.2439
|
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| Structure |
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|---|
| Simcomp |
|
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| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiglaucoma, beta-Adrenergic receptor antagonist |
|---|
| Comment |
Propranolol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C07 BETA BLOCKING AGENTS
C07A BETA BLOCKING AGENTS
C07AA Beta blocking agents, non-selective
C07AA19 Bupranolol
D01454 Bupranolol hydrochloride (JP18)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG00311 Bupranolol
D01454 Bupranolol hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D01454 Bupranolol hydrochloride (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01454 Bupranolol hydrochloride
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG00311 Bupranolol
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 19
1 X Cl 23.1661 -21.6550
2 O2a O 15.5189 -17.5651
3 C1b C 16.6944 -16.8737
4 C1c C 17.9391 -17.5651
5 C1b C 19.1837 -16.8737
6 O1a O 17.9391 -18.9481
7 N1b N 20.3592 -17.5651
8 C1d C 21.6039 -16.8737
9 C1a C 22.7900 -17.5848
10 C1a C 21.6267 -15.4909
11 C1a C 22.8128 -16.2020
12 C8y C 15.5189 -18.9651
13 C8y C 14.3203 -19.6573
14 C8x C 14.3205 -21.0573
15 C8x C 15.5330 -21.7572
16 C8y C 16.7316 -21.0650
17 C8x C 16.7314 -19.6650
18 X Cl 13.1356 -18.9734
19 C1a C 17.9451 -21.7654
BOND 18
1 2 3 1
2 3 4 1
3 4 5 1
4 4 6 1
5 5 7 1
6 7 8 1
7 8 9 1
8 8 10 1
9 8 11 1
10 2 12 1
11 12 13 2
12 13 14 1
13 14 15 2
14 15 16 1
15 16 17 2
16 12 17 1
17 13 18 1
18 16 19 1
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