KEGG   DRUG: Fosfomycin sodium
Entry
D02188                      Drug                                   
Name
Fosfomycin sodium (JP18);
Fosmicin S (TN)
Formula
C3H5O4P. 2Na
Exact mass
181.9721
Mol weight
182.0227
Structure
Simcomp
Remark
Therapeutic category: 1325 6135
ATC code: J01XX01 S02AA17
Chemical structure group: DG00633
Product (DG00633): D00925<US> D02187<JP> D02188<JP>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
UDP-N-acetylglucosamine 1-carboxyvinyltransferase [KO:K00790]
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01X OTHER ANTIBACTERIALS
    J01XX Other antibacterials
     J01XX01 Fosfomycin
      D02188  Fosfomycin sodium (JP18) <JP>
 S SENSORY ORGANS
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA17 Fosfomycin
      D02188  Fosfomycin sodium (JP18) <JP>
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Fosfomycin
    D02188  Fosfomycin sodium (JP18)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   132  Otic and nasal agents
    1325  Otolaryngologic antibiotics
     D02188  Fosfomycin sodium (JP18)
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6135  Fosfomycins
     D02188  Fosfomycin sodium (JP18)
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, other
   Other peptidoglycan biosynthesis inhibitor
    D02188  Fosfomycin sodium (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02188  Fosfomycin sodium
  D02188  Fosfomycin sodium for injection
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, other
   Other peptidoglycan biosynthesis inhibitor
    DG00633  Fosfomycin
Other DBs
CAS: 26016-99-9
PubChem: 7849248
ChEBI: 201404
LigandBox: D02188
NIKKAJI: J17.130A
LinkDB
KCF data

ATOM        10
            1   Z   Na   28.4891  -14.3848 #+
            2   Z   Na   31.9988  -18.1307 #+
            3   C1y C    32.5500  -14.8400
            4   C1y C    33.9500  -14.8400
            5   O2x O    33.2500  -13.6500
            6   P1b P    31.3600  -15.6100
            7   C1a C    35.1400  -15.6100
            8   O1c O    30.1000  -16.3100
            9   O1c O    30.6600  -14.3500 #-
            10  O1c O    32.0600  -16.8000 #-
BOND        8
            1     3   4 1
            2     4   5 1
            3     5   3 1
            4     3   6 1 #Up
            5     4   7 1 #Up
            6     6   8 2
            7     6   9 1
            8     6  10 1

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