| Entry |
|
|---|
| Name |
Levobetaxolol hydrochloride (USAN);
Betaxon (TN) |
|---|
| Formula |
C18H29NO3. HCl
|
|---|
| Exact mass |
343.1914
|
|---|
| Mol weight |
343.8887
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
|
|---|
| Efficacy |
Antiglaucoma, beta1-Adrenergic receptor antagonist |
|---|
| Comment |
Propranolol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
D04710 Levobetaxolol hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB1
D04710 Levobetaxolol hydrochloride (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 23
1 O2a O 18.4100 -17.4300
2 C1b C 19.6700 -16.7300
3 C1c C 20.8600 -17.4300
4 C1b C 22.0500 -16.7300
5 N1b N 23.3100 -17.4300
6 C1c C 24.5000 -16.7300
7 C1a C 25.6900 -17.4300
8 C1a C 24.5000 -15.4000
9 O1a O 20.8600 -18.8300
10 C8y C 18.4100 -18.8300
11 C8x C 17.2200 -19.5300
12 C8x C 17.2200 -20.9300
13 C8y C 18.3400 -21.6300
14 C8x C 19.6000 -20.9300
15 C8x C 19.6000 -19.5300
16 C1b C 18.3400 -23.0300
17 C1b C 17.0800 -23.7300
18 O2a O 15.8900 -22.9600
19 C1b C 14.7000 -23.6600
20 C1y C 13.5100 -22.9600
21 C1x C 12.1100 -22.9600
22 C1x C 12.8100 -21.7700
23 X Cl 25.5024 -22.6913
BOND 23
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 6 7 1
7 6 8 1
8 3 9 1 #Down
9 1 10 1
10 10 11 2
11 11 12 1
12 12 13 2
13 13 14 1
14 14 15 2
15 10 15 1
16 13 16 1
17 16 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 21 20 1
22 22 21 1
23 22 20 1
|
|---|
