| Entry |
|
|---|
| Name |
Betaxolol (INN);
Betaxolol (TN) |
|---|
| Formula |
C18H29NO3
|
|---|
| Exact mass |
307.2147
|
|---|
| Mol weight |
307.4278
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
DG03231 Antihypertensive
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
| Product (DG00315): | D00598<JP/US> |
|
|---|
| Efficacy |
Antiglaucoma, Antihypertensive, beta1-Adrenergic receptor antagonist |
|---|
| Comment |
Propranolol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C07 BETA BLOCKING AGENTS
C07A BETA BLOCKING AGENTS
C07AB Beta blocking agents, selective
C07AB05 Betaxolol
D07526 Betaxolol (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01ED Beta blocking agents
S01ED02 Betaxolol
D07526 Betaxolol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
DG00315 Betaxolol
D07526 Betaxolol
DG03231 Antihypertensive
DG00315 Betaxolol
D07526 Betaxolol
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG00315 Betaxolol
D07526 Betaxolol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB1
D07526 Betaxolol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01461 beta1-Adrenergic receptor antagonist
DG00315 Betaxolol
DG03231 Antihypertensive
DG00315 Betaxolol
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG00315 Betaxolol
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 22
1 O2a O 20.5100 -14.6300
2 C1b C 21.7000 -13.9300
3 C1c C 22.9600 -14.6300
4 C1b C 24.1500 -13.9300
5 O1a O 22.9600 -16.0300
6 N1b N 25.3400 -14.6300
7 C1c C 26.6000 -13.9300
8 C1a C 27.7900 -14.6300
9 C1a C 26.6000 -12.5300
10 C8y C 20.5100 -16.0300
11 C8x C 19.3200 -16.7300
12 C8x C 19.3200 -18.1300
13 C8y C 20.5100 -18.8300
14 C8x C 21.7000 -18.1300
15 C8x C 21.7000 -16.7300
16 C1b C 20.5100 -20.2300
17 C1b C 19.3200 -21.0000
18 O2a O 18.1300 -20.3000
19 C1b C 16.9400 -21.0000
20 C1y C 15.6800 -20.3700
21 C1x C 14.2800 -20.3700
22 C1x C 14.9800 -19.1800
BOND 23
1 1 2 1
2 2 3 1
3 3 4 1
4 3 5 1
5 4 6 1
6 6 7 1
7 7 8 1
8 7 9 1
9 1 10 1
10 10 11 2
11 11 12 1
12 12 13 2
13 13 14 1
14 14 15 2
15 10 15 1
16 13 16 1
17 16 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 21 20 1
22 22 21 1
23 22 20 1
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