| Entry |
|
|---|
| Name |
Chloramphenicol succinate;
Chloramphenicol ICN (TN) |
|---|
| Formula |
C15H16Cl2N2O8
|
|---|
| Exact mass |
422.0284
|
|---|
| Mol weight |
423.2021
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01576 Amphenicol type antibacterial
|
|---|
| Remark |
| Product (DG00399): | D00104<JP> D02185<JP/US> |
|
|---|
| Efficacy |
Antibacterial, Protein biosynthesis inhibitor |
|---|
| Comment |
Amphenicol derivative
Active form of prodrug: Chloramphenicol [DR: D00104]
|
|---|
| Target |
50S ribosomal subunit |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AX Other antibiotics for topical use
D06AX02 Chloramphenicol
D07675 Chloramphenicol succinate
D10 ANTI-ACNE PREPARATIONS
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AF Antiinfectives for treatment of acne
D10AF03 Chloramphenicol
D07675 Chloramphenicol succinate
G GENITO URINARY SYSTEM AND SEX HORMONES
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
G01AA Antibiotics
G01AA05 Chloramphenicol
D07675 Chloramphenicol succinate
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01B AMPHENICOLS
J01BA Amphenicols
J01BA01 Chloramphenicol
D07675 Chloramphenicol succinate
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA01 Chloramphenicol
D07675 Chloramphenicol succinate
S02 OTOLOGICALS
S02A ANTIINFECTIVES
S02AA Antiinfectives
S02AA01 Chloramphenicol
D07675 Chloramphenicol succinate
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03A ANTIINFECTIVES
S03AA Antiinfectives
S03AA08 Chloramphenicol
D07675 Chloramphenicol succinate
Drug groups [BR:br08330]
Antibacterial
DG01576 Amphenicol type antibacterial
DG00399 Chloramphenicol
D07675 Chloramphenicol succinate
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Amphenicol
D07675 Chloramphenicol succinate
Prodrugs [br08324.html]
D07675
Drug groups [BR:br08330]
Antibacterial
DG01576 Amphenicol type antibacterial
DG00399 Chloramphenicol
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Amphenicol
DG00399 Chloramphenicol
Prodrugs [br08324.html]
DG00399
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 27
1 C8y C 21.4900 -15.5400
2 C1c C 21.4900 -16.9400
3 C8x C 20.3000 -14.7700
4 C8x C 22.7500 -14.7700
5 C1c C 22.7500 -17.5700
6 O1a O 20.3000 -17.5700
7 C8x C 20.3000 -13.3700
8 C8x C 22.7500 -13.3700
9 N1b N 23.9400 -16.9400
10 C8y C 21.4900 -12.7400
11 C5a C 25.1300 -17.6400
12 N2b N 21.4900 -11.3400 #+
13 C1c C 26.3200 -16.9400
14 O5a O 25.1300 -18.9700
15 O3a O 20.3000 -10.6400
16 O3a O 22.6800 -10.6400 #-
17 X Cl 27.5100 -17.6400
18 X Cl 26.3200 -15.5400
19 C1b C 22.7500 -19.0400
20 O7a O 21.4900 -19.7400
21 C7a C 21.4900 -21.1400
22 O6a O 20.3000 -21.8400
23 C1b C 22.7500 -21.8400
24 C1b C 24.0100 -21.1400
25 C6a C 25.2000 -21.8400
26 O6a O 26.3900 -21.1400
27 O6a O 25.2000 -23.3100
BOND 27
1 5 9 1
2 7 10 2
3 9 11 1
4 10 12 1
5 11 13 1
6 11 14 2
7 12 15 2
8 12 16 1
9 13 17 1
10 13 18 1
11 8 10 1
12 1 2 1
13 1 3 2
14 1 4 1
15 2 5 1
16 2 6 1 #Down
17 3 7 1
18 4 8 2
19 5 19 1
20 19 20 1
21 20 21 1
22 21 22 2
23 21 23 1
24 23 24 1
25 24 25 1
26 25 26 1
27 25 27 2
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