KEGG GLYCAN: G00060

GLYCAN: G00060

Entry

G00060                      Glycan

Name

III3Fuc-nLc4Cer;
III3-a-Fuc-nLc4Cer;
Lacto-N-fucopentaosyl III ceramide;
LNF III cer;
SSEA-1

Composition

(Gal)2 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1

Mass

835.8 (Cer)

Structure

Remark

Same as:

C22478

Reaction

R06025

Pathway

map00601

Glycosphingolipid biosynthesis - lacto and neolacto series

map01100

Metabolic pathways

Network

nt06035 Blood group carbohydrate antigen biosynthesis

Enzyme

2.4.1.65 2.4.1.152 2.4.1.-

Brite

Lipids [BR:br08002]
SP  Sphingolipids
  SP05 Neutral glycosphingolipids
   SP0505 Galbeta1-4GlcNAcbeta1-3Galbeta1-4Glc- (Neolacto series)
    G00060  Gal-beta1->4(Fuc-alpha1->3)GlcNAc-beta1->3Gal-beta1->4Glc-beta1->1'Cer (SSEA-1)
Blood groups and carbohydrate antigens [br08110.html]
Lewis blood group
  G00060

Reference

1 [PMID:9111138]

Authors

Henry S, Jovall PA, Ghardashkhani S, Elmgren A, Martinsson T, Larson G, Samuelsson B.

Title

Structural and immunochemical identification of Le(a), Le(b), H type 1, and related glycolipids in small intestinal mucosa of a group O Le(a-b-) nonsecretor.

Journal

Glycoconj J 14:209-23 (1997)
DOI:10.1023/a:1018541821819

Reference

2 [PMID:2960671]

Authors

Holmes EH, Hakomori S, Ostrander GK.

Title

Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1----3N-acetylglucosaminyltransferase.

Journal

J Biol Chem 262:15649-58 (1987)

Reference

3 [PMID:2430018]

Authors

Umeda M, Diego I, Marcus DM.

Title

The occurrence of anti-3-fucosyllactosamine antibodies and their cross-reactive idiotopes in preimmune and immune mouse sera.

Journal

J Immunol 137:3264-9 (1986)

Other DBs

CCSD:

196 876 877 2673 2674 4955 5365 5562 8727 11666 11851 14081 14547 14854 14902 15555 16087 16292 16408 16465 16476 18489 18631 21105 21115 21322 22622 23140 23872 23892 23915 23933 25469 25847 25876 26169 26618 27474 28509 31688 32053 32744 33044 33202 33722 34834 35916 36116 38136 38373 41390 42844 44580 47565 49127

GlyTouCan:

LIPIDMAPS:

JCGGDB:

LipidBank:

GlycoEpitope:

LinkDB

KCF data

NODE        6
            1   Cer        13     0
            2   Glc         5     0
            3   Gal        -3     0
            4   GlcNAc    -12     0
            5   Gal       -21     4
            6   LFuc      -21    -4
EDGE        5
            1     2:b1    1:1
            2     3:b1    2:4
            3     4:b1    3:3
            4     5:b1    4:4
            5     6:a1    4:3

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