KEGG   GLYCAN: G00097
Entry
G00097                      Glycan                                 
Name
Galactosylgloboside;
SSEA-3;
Gb5Cer
Composition
(Gal)3 (GalNAc)1 (Glc)1 (Cer)1
Mass
851.8 (Cer)
Structure
Remark
Same as: C22468
Reaction
Pathway
map00603  Glycosphingolipid biosynthesis - globo and isoglobo series
map01100  Metabolic pathways
Network
nt06035  Blood group carbohydrate antigen biosynthesis
Enzyme
2.4.1.69        2.4.1.-         2.4.3.2
Brite
Lipids [BR:br08002]
 SP  Sphingolipids
  SP05 Neutral glycosphingolipids
   SP0502 Galalpha1-4Galbeta1-4Glc- (Globo series)
    G00097  Gal-beta1->3GalNAc-beta1->3Gal-alpha1->4Gal-beta1->4Glc-beta1->1'Cer
Cancer-associated carbohydrates [br08441.html]
 Glycosphingolipid
  G00097
Reference
1  [PMID:8625206]
  Authors
Ohyama C, Orikasa S, Kawamura S, Satoh M, Saito S, Fukushi Y, Levery SB, Hakomori S.
  Title
Galactosylgloboside expression in seminoma. Inverse correlation with metastatic potential.
  Journal
Reference
2  [PMID:12227795]
  Authors
Bosse F, Marcaurelle LA, Seeberger PH.
  Title
Linear synthesis of the tumor-associated carbohydrate antigens Globo-H, SSEA-3, and Gb3.
  Journal
J Org Chem 67:6659-70 (2002)
DOI:10.1021/jo025834+
Reference
3  [PMID:7595524]
  Authors
Dasgupta S, Hogan EL, van Halbeek H.
  Title
Chemical and immunological characterization of galactosyl-beta 1-3-globoside in bovine, human, and rat brain.
  Journal
J Neurochem 65:2344-9 (1995)
DOI:10.1046/j.1471-4159.1995.65052344.x
Other DBs
LinkDB
KCF data

NODE        6
            1   Cer      20.4     0
            2   Glc      12.4     0
            3   Gal       4.4     0
            4   Gal      -3.6     0
            5   GalNAc  -12.6     0
            6   Gal     -21.6     0
EDGE        5
            1     2:b1    1:1  
            2     3:b1    2:4  
            3     4:a1    3:4  
            4     5:b1    4:3  
            5     6:b1    5:3

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