KEGG   ORTHOLOGY: K00186
Entry
K00186                      KO                                     
Symbol
vorA
Name
2-oxoisovalerate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.7]
Pathway
map00280  Valine, leucine and isoleucine degradation
map01100  Metabolic pathways
map01210  2-Oxocarboxylic acid metabolism
Reaction
R07160  3-methyl-2-oxobutanoate:ferredoxin oxidoreductase (decarboxylating;CoA-2-methylpropanoylating)
R08566  4-methyl-2-oxopentanoate:ferredoxin oxidoreductase (decarboxylating; CoA-3-methylbutanoylating)
R08567  (S)-3-methyl-2-oxopentanoate:ferredoxin oxidoreductase (decarboxylating; CoA-2-methylbutanoylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    K00186  vorA; 2-oxoisovalerate ferredoxin oxidoreductase alpha subunit
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.7  With an iron-sulfur protein as acceptor
    1.2.7.7  3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
     K00186  vorA; 2-oxoisovalerate ferredoxin oxidoreductase alpha subunit
Enzymes of 2-oxocarboxylic acid metabolism [br01601.html]
 2-Oxoacid oxidizing enzymes
  K00186
Other DBs
COG: COG0674
GO: 0043807
Genes
HMR: Hipma_0797
DAV: DESACE_01540(porA)
PEF: A7E78_02855
DEK: DSLASN_10400(porA_1)
AFW: Anae109_4114
AORY: AMOR_34170(porA)
FWA: DCMF_13980
CALK: HUE98_02350(porA)
PBU: L21SP3_01137(korA_1)
PBP: STSP1_01192(korA_1)
PBAS: SMSP2_01216(korA)
VBC: C5Q97_08005
SLR: L21SP2_0406
ABA: Acid345_0952
ORP: MOP44_03550(vorB)
SUS: Acid_1871
PFER: IRI77_33005
THYD: TTHT_1225(porA)
GEX: GETHOR_18790
GEP: Q9293_11035(vorB)
CABY: Cabys_3126
MMP: MMP1272(vorB)
MMQ: MmarC5_0319
MMX: MmarC6_1401
MMZ: MmarC7_0518
MMD: GYY_07195
MMAK: MMKA1_14970
MMAO: MMOS7_13790
MMAD: MMJJ_15730(korA_3)
MVN: Mevan_0584
MVO: Mvol_0719
MTH: MTH_704
MMG: MTBMA_c10910(vorB)
MWO: MWSIV6_1080(vorB)
MTEE: MTTB_10550
METC: MTCT_0632
METE: tca_00679(korA_2)
METZ: METMT2_0338
METK: FVF72_08030
MTHM: FZP57_05125
METJ: FZP68_01100
MRU: mru_1432(vorA)
MSI: Msm_0332
MMIL: sm9_0693(vorA)
MOL: YLM1_0933
MARO: MarbSA_03670
METV: K4897_02175
MEL: Metbo_2453
MEW: MSWAN_0188
METH: MBMB1_0179(vorB)
MFC: BRM9_2124(vorA)
MFI: DSM1535_1556(vorB)
MCUB: MCBB_0194(vorB)
MSUB: BK009_10650
METN: BK008_06275
METT: CIT01_01275
METO: CIT02_06145
MEME: HYG87_02765
MFEG: GCM10025860_09920
MFV: Mfer_0416
AST: Asulf_00880
GAC: GACE_2154
GAH: GAH_00571
PFU: PF0969
PFI: PFC_04075(vorA)
PHO: PH0680(PH0680)
PAB: PAB1472
PYN: PNA2_1294
PYA: PYCH_06640
PYS: Py04_1080
PYC: TQ32_04855(porA)
TKO: TK1980
TON: TON_1478
TGA: TGAM_0265(vorA)
TSI: TSIB_1382
TBA: TERMP_01558
THE: GQS_08130(vorA)
THA: TAM4_1460
THM: CL1_1247
TLT: OCC_07491(porA)
THS: TES1_1553
TNU: BD01_1943
TEU: TEU_01675(porA)
TGY: X802_03765(porA)
THV: ADU37_CDS14450
TCH: CHITON_0667
TPEP: A0127_05005(porA)
TPIE: A7C91_04900(porA)
TGG: A3K92_07965(porA)
TCE: A3L02_06805(porA)
TBS: A3L01_08190(porA)
THH: CDI07_07390(porA)
TSL: A3L11_01540(porA)
TTD: A3L14_10585(porA)
TPRF: A3L09_01315(porA)
TRL: A3L10_07580(porA)
TPAF: A3L08_01315(porA)
THY: A3L12_04025(porA)
TIC: FH039_11785(porA)
TCQ: TIRI35C_1961(vorA)
THEM: FPV09_09750(porA)
THEI: K1720_10005(porA)
PPAC: PAP_04310(porA)
MBA: Mbar_A2174
MBY: MSBRM_2263
MBW: MSBRW_2567
MBAR: MSBR2_0148
MBAK: MSBR3_1065
MAC: MA_2910(vorB)
MMA: MM_3182(vorB)
MMAZ: MmTuc01_3278
MMJ: MSMAS_1507
MMAC: MSMAC_2850
MVC: MSVAZ_1287
MEK: MSKOL_1231
MLS: MSLAZ_2009
METM: MSMTP_1762
MEF: MSWH1_1308
MEQ: MSWHS_1392
MSJ: MSSAC_2722
MSZ: MSSIH_1392
MSW: MSSIT_1430
MTHR: MSTHT_0825
MTHE: MSTHC_2446
MHOR: MSHOH_1580
MFZ: AOB57_012380(vorB)
MBU: Mbur_0606
MMET: MCMEM_1078
MELO: J7W08_03850
MMH: Mmah_1011
MHAZ: BHR79_08515
MPOT: BKM01_04765
MZH: Mzhil_0903
MPY: Mpsy_0060
MZI: HWN40_07265
MMAV: RE476_03230
MSEB: RE474_12880
MHZ: Metho_2049
MEHF: MmiHf6_00130(korA)
MEES: MmiEs2_10530(korA)
MTP: Mthe_0156
MCJ: MCON_0779(vorB)
MHI: Mhar_0584
HAHS: HSRCO_0563(porA2)
TAC: Ta0628
MEAR: Mpt1_c05550(vorB)
ABI: Aboo_0300
ACF: AciM339_0764
IAG: Igag_1136
STO: STK_15320
SOH: D1869_08595
SSO: SSO1207(porA-1)
SOL: Ssol_2171
SSOA: SULA_2206
SSOL: SULB_2207
SSOF: SULC_2204
SSHI: J5U23_01993
SIS: LS215_0396
SIA: M1425_0372
SIM: M1627_0380
SID: M164_0396
SIY: YG5714_0374
SIN: YN1551_2681
SII: LD85_0384
SIH: SiH_0373
SIR: SiRe_0364
SIC: SiL_0352
SULE: GFS03_03425
SULO: GFS33_07805
SULL: EWF20_09765
MTEN: GWK48_07885
AMAN: B6F84_13225
ASUL: DFR86_11210
SMET: RQ359_000910
CCAI: NAS2_0099 NAS2_0791
LOB: NEF87_002289
PSYT: DSAG12_00253(vorA_1)
 » show all
Reference
PMID:8550513 (P.furiosus)
  Authors
Heider J, Mai X, Adams MW
  Title
Characterization of 2-ketoisovalerate ferredoxin oxidoreductase, a new and reversible coenzyme A-dependent enzyme involved in peptide fermentation by hyperthermophilic archaea.
  Journal
J Bacteriol 178:780-7 (1996)
DOI:10.1128/JB.178.3.780-787.1996
Reference
PMID:8550425
  Authors
Kletzin A, Adams MW
  Title
Molecular and phylogenetic characterization of pyruvate and 2-ketoisovalerate ferredoxin oxidoreductases from Pyrococcus furiosus and pyruvate ferredoxin oxidoreductase from Thermotoga maritima.
  Journal
J Bacteriol 178:248-57 (1996)
DOI:10.1128/JB.178.1.248-257.1996
  Sequence
[pfu:PF0969]
Reference
PMID:9108258
  Authors
Tersteegen A, Linder D, Thauer RK, Hedderich R
  Title
Structures and functions of four anabolic 2-oxoacid oxidoreductases in Methanobacterium thermoautotrophicum.
  Journal
Eur J Biochem 244:862-8 (1997)
DOI:10.1111/j.1432-1033.1997.00862.x
  Sequence
[mmg:MTBMA_c10910]
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