KEGG ORTHOLOGY: K00277

ORTHOLOGY: K00277

Entry

K00277                      KO

Symbol

LOX

Name

protein-lysine 6-oxidase [EC:1.4.3.13]

Disease

H00801

Familial thoracic aortic aneurysm and dissection

Brite

KEGG Orthology (KO) [BR:ko00001]
09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    K00277  LOX; protein-lysine 6-oxidase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.4  Acting on the CH-NH2 group of donors
   1.4.3  With oxygen as acceptor
    1.4.3.13  protein-lysine 6-oxidase
     K00277  LOX; protein-lysine 6-oxidase

Other DBs

GO:

0004720

Genes

HSA:

4015(LOX)

PTR:	471614(LOX)

PPS:	100978437(LOX)

GGO:	101136249(LOX)

PON:	100457685(LOX)

NLE:	100605848(LOX)

HMH:	116470894(LOX)

MCC:	699997(LOX)

MCF:	102132184(LOX)

MTHB:

126957529

MNI:	105500045(LOX)

CSAB:

103244411(LOX)

CATY:

105599668(LOX)

PANU:

101009863(LOX)

TGE:	112625888(LOX)

MLEU:

105545034(LOX)

RRO:	104666992(LOX)

RBB:	108520384(LOX)

TFN:	117065963(LOX)

PTEH:

111530193(LOX)

CANG:

105527394(LOX)

CJC:	100407991(LOX)

SBQ:	101048786(LOX)

CIMI:

108306781(LOX)

MMUR:

105884562(LOX)

LCAT:

123648610(LOX)

PCOQ:

105826346(LOX)

OGA:	100957484(LOX)

MMU:	16948(Lox)

MCAL:

110284684(Lox)

MPAH:

110333071(Lox)

RNO:	24914(Lox)

MCOC:

116087156(Lox)

ANU:	117719781(Lox)

MUN:	110561997(Lox)

CGE:

100764517

MAUA:

101827746(Lox)

PROB:

127234043(Lox)

PLEU:

114694772(Lox)

MORG:

121441932 121453380

MFOT:

126506023

AAMP:

119814493(Lox)

NGI:	103739770(Lox)

HGL:	101724460(Lox)

CCAN:

109686562(Lox)

DSP:	122103966(Lox)

PLOP:

125352074(Lox)

NCAR:

124987504

MMMA:

107143186(Lox)

OCU:

100357045

OPI:	101536754(LOX)

TUP:	102485593(LOX)

GVR:	103594373(LOX)

CFA:	481478(LOX)

CLUD:

112649935(LOX)

VVP:	112910209(LOX)

VLG:	121495447(LOX)

NPO:	129494909(LOX)

AML:	100471188(LOX)

UMR:	103670545(LOX)

UAH:	113261637(LOX)

UAR:	123790423(LOX)

ELK:

111148308

LLV:

125100791

MPUF:

101674938(LOX)

MNP:	132028872(LOX)

MLK:	131832565(LOX)

NVS:	122916359(LOX)

ORO:	101373448(LOX)

EJU:	114209620(LOX)

ZCA:	113929629(LOX)

MLX:	118016567(LOX)

NSU:	110591030(LOX)

LWW:	102749417(LOX)

FCA:	101092985(LOX)

PYU:	121010594(LOX)

PBG:	122486687(LOX)

PVIV:

125168681(LOX)

LRUF:

124522216

PPAD:

109278881(LOX)

PUC:

125935424

AJU:

106975167

HHV:	120219985(LOX)

BTA:	280841(LOX)

BOM:	102276831(LOX)

BIU:	109561863(LOX)

BBUB:

102397091(LOX)

BBIS:

104993159(LOX)

CHX:	102169472(LOX)

OAS:	101112220(LOX)

BTAX:

128051553(LOX)

ODA:	120864680(LOX)

CCAD:

122440080(LOX)

MBEZ:

129559069(LOX)

SSC:	100525278(LOX)

CFR:	102512711(LOX)

CBAI:

105082060(LOX)

CDK:	105105055(LOX)

VPC:	102536056(LOX)

BACU:

103012553(LOX)

BMUS:

118892905(LOX)

LVE:	103078614(LOX)

OOR:	101269698(LOX)

DLE:	111182358(LOX)

PCAD:

102993985(LOX)

PSIU:

116750841(LOX)

NASI:

112407735(LOX)

ECB:	100064016(LOX)

EPZ:	103557838(LOX)

EAI:	106842835(LOX)

MYB:	102253224(LOX)

MMYO:

118656205(LOX)

MLF:	102421922(LOX)

PKL:	118702754(LOX)

EFUS:

103285926(LOX)

MNA:	107540921(LOX)

DRO:	112315003(LOX)

SHON:

118975159(LOX)

AJM:	119063969(LOX)

PDIC:

114510267(LOX)

PHAS:

123818134(LOX)

MMF:	118641778(LOX)

PPAM:

129083877(LOX)

HAI:	109379076(LOX)

RFQ:	117025039(LOX)

PALE:

102888004(LOX)

PGIG:

120590869(LOX)

PVP:	105290866(LOX)

RAY:	107511146(LOX)

MJV:	108390293(LOX)

TOD:	119243553(LOX)

SARA:

101543655(LOX)

SETR:

126006071(LOX)

LAV:	100658633(LOX)

TMU:

101355891

ETF:	101641772(LOX)

DNM:	101420519(LOX)

MDO:	100027065(LOX)

GAS:	123231345(LOX)

SHR:	100920619(LOX)

AFZ:

127562288

PCW:	110223807(LOX)

OAA:	100076972(LOX)

GGA:	396474(LOX)

PCOC:

116239888(LOX)

CJO:	107306724(LOX)

TPAI:

128089319(LOX)

LMUT:

125686608(LOX)

NMEL:

110389631(LOX)

APLA:

101796992(LOX)

CATA:

118258310(LOX)

AFUL:

116500630(LOX)

TGU:	100223043(LOX)

LSR:	110479174(LOX)

PMOA:

120513571(LOX)

OTC:	121331504(LOX)

PRUF:

121362571(LOX)

FAB:	101817182(LOX)

OMA:	130264869(LOX)

PHI:	102109004(LOX)

PMAJ:

107216161(LOX)

CCAE:

111941266(LOX)

CCW:	104690454(LOX)

ETL:	114055337(LOX)

ZAB:	102061613(LOX)

ZLE:	135459935(LOX)

SVG:	106851991(LOX)

MMEA:

130574497(LOX)

HRT:	120765874(LOX)

FPG:	101917045(LOX)

FCH:	102050081(LOX)

TALA:

104363843(LOX)

ACHC:

115336592(LOX)

HLE:	104828196(LOX)

AGEN:

126036194

GCL:

127027612

SHAB:

115619594(LOX)

DPUB:

104300375(LOX)

RTD:	128902241(LOX)

CUCA:

104061078(LOX)

AROW:

112974482(LOX)

DNE:	112992377(LOX)

AMJ:	102559899(LOXL5B) 102571028(LOX)

CPOO:

109323579(LOX) 109324851

GGN:

109294688

CMY:	102941654(LOX)

CCAY:

125636403(LOX)

DCC:	119855933(LOX)

CPIC:

101944676(LOX)

TST:	117879055(LOX)

CABI:

116831038(LOX)

MRV:	120408464(LOX)

ACS:	100558882(lox)

ASAO:

132767234(LOX) 132781535

PVT:	110072652 110084345(LOX)

SUND:

121923132(LOX) 121937079

PBI:	103066382(LOX)

CTIG:

120301974(LOX) 120305337

TSR:	106540749(LOX)

PGUT:

117674681(LOX)

APRI:

131188274

PTEX:

113449331(LOX)

NSS:	113415978(LOX) 113425514

VKO:	123031240(LOX)

PMUA:

114588561 114606468(LOX)

PRAF:

128405902 128423259(LOX)

ZVI:	118076839(LOX) 118086060

HCG:	128347651(LOX) 128347899

GJA:	107121950(LOX)

STOW:

125432735 125436326(LOX)

EMC:	129334917(LOX)

XLA:	108707204(lox.S) 734204(lox.L)

XTR:	780067(lox)

NPR:	108791659 108799190(LOX)

RTEM:

120913806 120932053(LOX)

BBUF:

120988464(LOX) 120990934

BGAR:

122928991(LOX)

MUO:	115463222(LOX) 115481119

GSH:	117352545 117352546 117364560

DRE:	100124531(loxl5b) 103911450 404621(loxa)

SRX:	107713278 107726222 107733348 107740551 107744153 107744154

SANH:

107686455 107687932 107688470(lox) 107696862 107698563 107704580

SGH:	107549379 107562574 107566396(lox) 107569406 107578202 107596248

CCAR:

109052012 109057450 109073443 109087603 109087612 109087621 109100885 109101193 109101345

CAUA:

113045254 113046247 113052788 113052841 113054132 113074970 113087085 113094196 113099105 113106902 113110400 113111892

CGIB:

127965825 128021370 128023927

PTET:

122335626(loxl5b) 122352893(loxa)

LROH:

127172553(loxa) 127174597(loxl5b)

OMC:	131526694(loxl5b) 131548747(loxa)

PPRM:

120474938(loxl5b) 120481978(loxa)

RKG:	130075350(loxl5b) 130087109(loxa)

MAMB:

125250714(loxl5b) 125256564(loxa)

CIDE:

127505324 127520622

MASI:

127432759 127433256 127441443 127442681

TROS:

130545672(loxa) 130554608(loxl5b)

TDW:	130411704(loxa) 130417809(loxl5b)

MANU:

129443445(loxl5b) 129447198(loxa)

IPU:	108265136 108277371(loxa) 108280695(loxl5b)

IFU:	128607811 128620096(loxa) 128624474(loxl5b)

PHYP:

113532232(lox) 113533206 113544153

SMEO:

124393997(loxa) 124400032 124402758(loxl5b)

TFD:	113645263(loxl5b) 113655978 113661327(loxa)

TVC:	132853529 132861011(loxl5b) 132863513(loxa)

TRN:	134302655(loxl5b) 134317984 134332315(loxa)

AMEX:

103032299 103038245 103039369(lox) 103043200

CMAO:

118797445(loxl5b) 118813247 118824968(loxa)

EEE:	113570987(lox) 113575169 113585954

CHAR:

105895569(loxa) 105900937(loxl5a) 105906924 105907551

TRU:	101062132 101070353 101079320

TFS:	130516903(loxa) 130525791 130528572(loxl5a) 130538654

TNG:	GSTEN00017324G001 GSTEN00027760G001 GSTEN00028864G001 GSTEN00031042G001

LCO:	104923293 104923472(lox) 104924628 104931423

NCC:	104944446 104953666 104961306

TBEN:

117472903 117476642(loxa) 117497759(loxl5a) 117500135(loxl5b)

CGOB:

115007100 115013610(lox) 115017234 115022107

PGEO:

117445750(loxl5a) 117452879 117456240(loxa) 117462514(loxl5b)

GACU:

117534818(loxl5a) 117541446 117558120(loxa)

EMAC:

134865552 134868927(loxa) 134869233(loxl5a) 134873907

ELY:	117251980 117254282(loxl5a) 117269322(loxa)

EFO:	125890830 125895663(loxl5a) 125901840 125906126(loxa)

PLEP:

121941192(loxl5a) 121951559 121959795(loxa) 121965070

SLUC:

116035105(loxa) 116045902(loxl5b) 116054423 116055490(loxl5a)

ECRA:

117944418 117950366(loxl5a) 117954214(loxl5b) 117959307(loxa)

ESP:	116690159(lox) 116696174 116698712

PFLV:

114555699 114561749 114565526 114571472

GAT:	120816563 120824413(loxl5a) 120832258(loxa)

PPUG:

119202456 119217197(loxl5a) 119225276 119226535(loxa)

AFB:	129089357 129094736(loxl5a) 129101416 129102371(loxa)

CLUM:

117729769(loxl5a) 117736053 117740408(loxa) 117746681(loxl5b)

PSWI:

130196724 130197590(loxl5b) 130205796(loxa)

MSAM:

119891852 119901390(loxl5a) 119901867 119914443(loxa)

SCHU:

122866044 122876811 122877980(loxl5a) 122886743

CUD:	121509897 121512378(loxl5a) 121520512 121525525(loxa)

ALAT:

119010578 119019237 119028907(loxl5a) 119029445(loxa)

MZE:	101470139 101477010 101483892

ONL:	100695665 100702891 100704050 100708791(lox)

OAU:	116313460 116313579 116322468(loxa) 116323169(loxl5a)

OLA:	101164730(lox) 101166747 101168667 101171929

OML:	112147810(loxl5b) 112150387 112150727(loxl5a) 112163226(loxa)

CSAI:

133450973 133451857 133455289(loxa) 133457803(loxl5a)

XMA:	102219592 102222632 102227597 102232659

XCO:	114145970 114150071 114150510 114154798

XHE:	116721188 116724972 116725320 116730483(lox)

PRET:

103464096 103470817(lox) 103473689 103479881

PFOR:

103138502 103138504 103146069 103148481 103148498 103152616(lox)

PLAI:

106938519 106942922 106945932(lox) 106950660 106955326 106959077

PMEI:

106914783 106918983(lox) 106925484 106927960 106933761 106933762

GAF:	122819453(loxa) 122827632 122838618(loxl5a) 122840972(loxl5b)

PPRL:

129365912 129366691(loxa) 129375011(loxl5a) 129377930(loxl5b)

CVG:	107084642(lox) 107092672 107094219 107100672

CTUL:

119771583(loxa) 119784849 119785803(loxl5a) 119787860(loxl5b)

GMU:	124869548(loxl5b) 124872327(loxa) 124873657(loxl5a) 124877397

NFU:	107372900 107383593 107386123(lox) 107393124

KMR:	108230650(loxl5a) 108232567(loxa) 108232849(loxl5b) 108245865

ALIM:

106511976 106514508 106516863 106533445

NWH:	119407822(loxl5a) 119412992 119414726(loxl5b) 119425020(loxa)

AOCE:

111565540 111567323 111568365 111585553

MCEP:

124997012(loxA) 125009514(loxl5a) 125010318(loxl5b) 125012806

CSEM:

103390487 103393429 103396464 103398001

POV:	109625786 109626121 109644542 109645284

SSEN:

122759948 122769856 122780697(loxl5a) 122781447(loxa)

HHIP:

117760716(loxl5a) 117772056(loxa) 117778753

HSP:	118114723 118118367(loxl5b) 118121146(loxl5a) 118126002(loxa)

PPLT:

128424821(loxa) 128437763 128448423(loxl5a) 128455156(loxl5b)

SMAU:

118285378(loxa) 118310561 118313937 118318781(loxl5a)

LCF:	108875130 108879892(loxa) 108881345 108884171(loxl5b)

SDU:	111231064 111232717 111234195 111239245

SLAL:

111645427 111650185 111668089(lox) 111669146

XGL:	120790981(loxl5a) 120799137 120805439 120806114(loxa)

HCQ:	109507291 109513468 109516887 109523566

SSCV:

125976089 125980091 125984542 125994128

SBIA:

133490761(loxa) 133499465 133504011(loxl5a) 133510899

PEE:	133400203 133406031(loxl5a) 133411962(loxl5b) 133413674(loxa)

PTAO:

133464996(loxa) 133475798 133481335(loxl5a) 133489353

BPEC:

110160052 110160517 110164111 110170694

MALB:

109955438 109963419 109967459

BSPL:

114845143 114854775(loxl5a) 114863196 114866810(loxa)

SJO:	128362227(loxl5a) 128364608 128368900(loxl5b) 128380725(loxa)

SASA:

100195194(lyox) 106564861(lox) 106569609 106573825 106585899 106600516

STRU:

115151734 115157530 115159447 115165018 115169282 115204186

OTW:	112219411 112226444 112231090(loxa) 112238492 112246614 112252183

OMY:	100189621(loxa) 110499862 110508305 110509899 110525209 110530787

OGO:	123991602 124007221(loxa) 124009306 124034678 124041694 124048845

ONE:	115101261 115101752 115108876 115116135 115120838 115124253

OKI:	109868574 109872314 109874026 109878301 109888539

OKE:	118371509 118385200 118387632 118392843 118394865 118401412

SALP:

111952944 111961509 111964111 111978867 112070768

SNH:	120020069 120021310 120026143 120050164 120054072 120056140

CCLU:

121535418 121541765(loxa) 121577141 121581269 121582403 121584349

ELS:	105011451 105014993 105021664(lox) 105022892

SFM:	108919826 108921520 108932061 108937978

PKI:	111847584 111849767 111856535

AANG:

118207126 118224965(loxl5a) 118229304

LOC:	102697184 102697992(lox)

PSPA:

121300708 121301656 121302574 121315403

ARUT:

117401353 117408559 117966201 117973219

PSEX:

120532701 120537645

LCM:	102364058(LOX) 102365752

CMK:	103188143(loxl5a)

RTP:

109932236

CPLA:

122560697 122565226

HOC:	132823680 132828823

LERI:

PMRN:

LRJ:

BFO:

BBEL:

DME:	Dmel_CG11335(Loxl1)

DGR:

CCAT:

BOD:

BDR:

RZE:	108353887 108375400

AOQ:

TDA:

SCAC:

LSQ:

GFS:

Reference

PMID:1685472

Authors

Hamalainen ER, Jones TA, Sheer D, Taskinen K, Pihlajaniemi T, Kivirikko KI

Title

Molecular cloning of human lysyl oxidase and assignment of the gene to chromosome 5q23.3-31.2.

Journal

Genomics 11:508-16 (1991)
DOI:10.1016/0888-7543(91)90057-l

Sequence

[hsa:4015]

LinkDB

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