KEGG   ORTHOLOGY: K00508
Entry
K00508                      KO                                     
Symbol
E1.14.19.3
Name
linoleoyl-CoA desaturase [EC:1.14.19.3]
Pathway
map00591  Linoleic acid metabolism
map01100  Metabolic pathways
Reaction
R07063  linoleoyl-CoA,hydrogen-donor:oxygen oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00591 Linoleic acid metabolism
    K00508  E1.14.19.3; linoleoyl-CoA desaturase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K00508  E1.14.19.3; linoleoyl-CoA desaturase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.3  acyl-CoA 6-desaturase
     K00508  E1.14.19.3; linoleoyl-CoA desaturase
Lipid biosynthesis proteins [BR:ko01004]
 Desaturase
  Front-end
   K00508  E1.14.19.3; linoleoyl-CoA desaturase
Other DBs
COG: COG3239
GO: 0016213
Genes
ECG: E2348C_1358
ENA: ECNA114_1401
ECOS: EC958_1504
ECC: c1695
ELN: NRG857_06320
ESE: ECSF_1212
EAB: ECABU_c15100
ELC: i14_1525
ELD: i02_1525
ELF: LF82_208
ECOJ: P423_06960
EFE: EFER_1726
EAL: EAKF1_ch0205c
EMA: C1192_05945
ESZ: FEM44_21185
EEC: EcWSU1_02601(des6)
ELG: BH714_08855
ESA: ESA_01449 ESA_01450
CSK: ES15_1651 ES15_1652
CSZ: CSSP291_07070 CSSP291_07075
CSJ: CSK29544_02752 CSK29544_02753
CCON: AFK62_11310 AFK62_11315
CDM: AFK67_11655 AFK67_11660
CMW: AFK63_06925 AFK63_06930
CTU: CTU_24860 CTU_24870
LPNU: KQ929_10745
SUPE: P0H77_12165
YSI: BF17_18735 BF17_18740
SMAR: SM39_2335 SM39_2336
SMAC: SMDB11_2131 SMDB11_2132
SMW: SMWW4_v1c28750 SMWW4_v1c28760
SPE: Spro_2862 Spro_2863
SRR: SerAS9_2954 SerAS9_2955
SRL: SOD_c26990(des1) SOD_c27000(des)
SRY: M621_14700 M621_14705
SRS: SerAS12_2955 SerAS12_2956
SRA: SerAS13_2956 SerAS13_2957
SLQ: M495_14805 M495_14810
SERF: L085_14410 L085_14415
SERS: SERRSCBI_13560 SERRSCBI_13565
SFW: WN53_23625 WN53_23630
SFG: AV650_19345 AV650_19350
SQU: E4343_01725 E4343_01730
SSUR: ATE40_010980 ATE40_010985
SURI: J0X03_09570 J0X03_09575
SENP: KHA73_14160 KHA73_14165
SNEM: NLX84_14490 NLX84_14495
SNEV: OI978_18120 OI978_18125
SGRI: SGBXF1_02913 SGBXF1_02914
SFO: Z042_22645 Z042_22650
RIU: I2123_14800
ECA: ECA0116
PATR: EV46_00590 EV46_00595
PATO: GZ59_01200 GZ59_01210
PCT: PC1_4135 PC1_4136
PCC: PCC21_001080 PCC21_001090
PCV: BCS7_00370 BCS7_00375
PWA: Pecwa_4416 Pecwa_4417
PPAR: A8F97_19355 A8F97_19360
PEC: W5S_4596 W5S_4597
PWS: A7983_08465 A7983_08470
PPOA: BJK05_17125 BJK05_17130
PBRA: B5S52_21360 B5S52_21365
PPUJ: E2566_20975 E2566_20980
PARI: I2D83_21425 I2D83_21430
PVZ: OA04_01280 OA04_01290
PPAV: LOZ86_01345 LOZ86_01350
PPOO: LW347_21025 LW347_21030
PACB: M9782_02805
PCOA: PJ912_13565
EPE: CI789_00700 CI789_00705
ERWI: GN242_04345 GN242_04350
ERP: LJN55_18055 LJN55_18060
PRG: RB151_029770(desA3) RB151_039160
PALA: CO695_07030
PHEI: NCTC12003_01329 NCTC12003_03452
PRQ: CYG50_01490 CYG50_19130
PRJ: NCTC6933_03440
PVC: G3341_06785 G3341_17290
PMAG: JI723_06695 JI723_17570
PHAG: PZ638_06530 PZ638_17835
MWI: MNY66_10115
LRI: NCTC12151_00626
RGL: CS053_14415
DTX: ATSB10_36650
DKO: I596_2530
PPSE: BN5_0558
PAVL: BKM03_28990
PSYI: MME58_25550
PSKU: KUIN1_50640
TOL: TOL_2040
TOR: R615_07535
OAI: OLEAN_C27500
BSAN: CHH28_12110
VCW: GJQ55_07790
OME: OLMES_1114
FPP: FPB0191_02197 FPB0191_02198
SALV: SALWKB2_0699
SCOM: PYG29_08790
CVI: CV_1644(desD) CV_2452
CVC: BKX93_02755 BKX93_21455
CHRI: DK842_15490
CHRB: DK843_21020
RMN: TK49_20560
RIN: ACS15_5784
RWE: KOL96_02900
BUB: BW23_4705
BSTG: WT74_24150
JAZ: YQ44_03125
JAL: BZG29_24440
JSV: CNX70_24830
JAS: FJQ89_14060
JLV: G3257_25145
JAH: JAB4_050380
JRI: P9875_25520
ETB: N7L95_24100
DMP: FAK_12480 FAK_41190
ADE: Adeh_1021
ACP: A2cp1_3380
AFW: Anae109_3187
ANK: AnaeK_0374 AnaeK_1080
AORY: AMOR_37230
MYX: QEG98_06420
CCX: COCOR_07436(des6)
SUR: STAUR_0738
AGE: AA314_05794
MBD: MEBOL_001021 MEBOL_004617
HOH: Hoch_5632
BSED: DN745_02880 DN745_05975
PCAY: FRD00_03300 FRD00_23105
SYN: sll0262(desD(des6))
SYZ: MYO_119490(desD(des6))
SYY: SYNGTS_1931(desD)
SYT: SYNGTI_1930(desD)
SYS: SYNPCCN_1929(desD)
SYQ: SYNPCCP_1929(desD)
SYJ: D082_30330(desD)
SYO: C7I86_10070
SYNP: Syn7502_02943
CGC: Cyagr_2722
AMR: AM1_1073
KOV: K9N68_09575
PSER: ABRG53_2437
PGX: OA858_22390
GEE: GM3708_945
MAR: MAE_48160(desD)
MPK: VL20_3454
MIQ: B5D77_04380
MVZ: myaer102_21530(desD)
ARP: NIES39_J03090(desD)
LFS: HFV01_08435
OAC: Oscil6304_3294
MIC: Mic7113_1421
AWA: AA650_11345 AA650_11350
HBQ: QI031_00935
CALT: Cal6303_1445
CALN: NIES2098_27880(desD)
CALS: NIES3974_16680(desD)
RIV: Riv7116_4400
MDP: NIES3275_51850(desD)
NSPH: BDGGKGIB_02538(desA3)
TOQ: HCG51_19350
ALAX: NIES50_15150(desD)
PUV: PUV_10250(des6)
WCH: wcw_0161
AMOB: HG15A2_45670(desA3)
FMR: Fuma_00671(desA)
GES: VT84_04450 VT84_12735
GOG: C1280_12875
GMS: SOIL9_48780 SOIL9_57870
FTJ: FTUN_3002
TSPH: KIH39_09120
SACI: Sinac_0398
HBS: IPV69_24075
TPX: Turpa_1866
ADIN: H7849_03985
MCOS: GM418_05800 GM418_21175 GM418_23330
CPI: Cpin_5676 Cpin_5677
CBAE: COR50_08285
CHIT: FW415_01170 FW415_18530
CHIH: GWR21_29075
CFIL: MYF79_18645
CHF: KTO58_22430
CHOR: MKQ68_03065 MKQ68_16115
CSAC: SIO70_03010 SIO70_19005 SIO70_30580
NKO: Niako_0028 Niako_2214 Niako_5619 Niako_6564
NSO: NIASO_08625
NIA: A8C56_04725
NYN: U0035_04485 U0035_07075
FLA: SY85_04130 SY85_23690 SY85_23835
FGG: FSB75_19400
ARB: A9P82_07590 A9P82_12885
ARK: D6B99_14620
AGI: FSB73_05040 FSB73_09885 FSB73_11865
ATEE: K9M52_05815 K9M52_10175
ARAC: E0W69_012610
FLN: FLA_2034 FLA_3880
PSEG: D3H65_02955 D3H65_14270 D3H65_21685
PGIN: FRZ67_13380 FRZ67_21700
PGO: FSB84_05680 FSB84_28195
FLS: GLV81_10500
LACS: H4075_12235 H4075_17930
FEI: K9M53_08205
FLP: LK994_06745 LK994_09070 LK994_14080
FLC: KJS93_09095 KJS93_09225 KJS93_12245 KJS93_12775 KJS93_13655
FLV: KJS94_07185 KJS94_10255 KJS94_17800
SEDT: TEGAF0_01790
THEO: IMW88_05580 IMW88_06715
HHY: Halhy_3263 Halhy_3651
SGN: SGRA_0953 SGRA_3738
PHE: Phep_0579
PEP: AQ505_23795
PCM: AY601_0291
PSTY: BFS30_12445
PEK: FFJ24_000610 FFJ24_000615 FFJ24_009255
PROE: H9L23_04740 H9L23_11790
PEX: IZT61_16130
PMUO: LOK61_08145
PRK: H9N25_10080
PGJ: QG516_17325
PSN: Pedsa_0092
SHG: Sph21_1254
SHT: KO02_08730
SPHN: BV902_16925
SMIZ: 4412673_01383(desA3_1) 4412673_04012(desA3_2)
SPSC: E2P86_12690 E2P86_12970
SPHE: GFH32_00630 GFH32_03190 GFH32_06585 GFH32_11525
SPDR: G6053_13355
SDJ: NCTC13534_02135(desA3)
SSPI: I6J01_08990
SSIY: JVX97_14820
SFAE: MUK51_09655
SBAM: SCB77_22100
SCN: Solca_2015
SLAS: L2B55_10575
MGIN: FRZ54_12455
MDJ: LLH06_12505
AGD: FRZ59_03065 FRZ59_14730
OLI: FKG96_03215
SBX: CA265_00630 CA265_00635 CA265_10185
CMR: Cycma_1461
CAMU: CA2015_1137 CA2015_1138 CA2015_1357 CA2015_4277
BBD: Belba_0611 Belba_0817
EVI: Echvi_1008 Echvi_2487
EST: DN752_11560 DN752_18445
ECHI: FKX85_04965 FKX85_20520
EMAI: KZP23_05365
ALM: AO498_08640
ALGO: GYM62_06400 GYM62_12700
MDA: IPZ59_05475 IPZ59_05660 IPZ59_16190
CHU: CHU_3762 CHU_3764
SLI: Slin_4655
SRD: SD10_21800
SMON: AWR27_12490
SPIR: CWM47_23570
SPIK: EXU85_12795
SPIB: G8759_25875
STAE: HNV11_11570 HNV11_21120
SOQ: LQ777_30240
SFOL: H3H32_15745 H3H32_16765
SENF: GJR95_40500
RHOZ: GXP67_00645 GXP67_00790 GXP67_19925 GXP67_34085 GXP67_34095
EMZ: MB380_12550
ALS: DJ013_11725
MAQA: LAG90_05115 LAG90_08950 LAG90_18070
DFE: Dfer_0898 Dfer_3204
DSN: HWI92_21275
DYC: NFI80_21445
DFQ: NFI81_00830 NFI81_22590
DCN: MUK70_26880
DPF: ON006_21660
RSI: Runsl_2603 Runsl_4114
RUN: DR864_01875 DR864_13000
RUP: DTQ70_15945
FAE: FAES_3358 FAES_4414(desD)
FIB: A6C57_20910
FLI: Fleli_2211 Fleli_3763
HSW: Hsw_0774 Hsw_3072
HYM: N008_13645
HYD: PK28_13650
HYE: AM218_02795
HYG: AUC43_10760 AUC43_17580
HYP: A0257_10485
HYZ: AXW84_22490
HNV: DDQ68_16005
HYH: D3Y59_00565
HYJ: FHG12_14055 FHG12_18880
HRS: HER32_05380 HER32_10030
HBN: GUY19_19465 GUY19_19470
HTS: HMJ29_01695 HMJ29_10905
HMT: MTP16_22770
HTB: MTX78_16955
HYK: O9Z63_11765
HSK: H4317_05740 H4317_05745 H4317_07045
HCW: O3303_09875
HSB: MWH26_12760 MWH26_17065
HAEI: MUN82_13020
HVL: MUN86_16805
HCF: MUN80_23735 MUN80_23740
PKO: PKOR_12515 PKOR_12520 PKOR_15525
PACT: CA264_02175 CA264_03165 CA264_03620
PONT: C1N53_08975 C1N53_09015
RUF: TH63_04060 TH63_14235
RTI: DC20_14245 DC20_14660
RUD: TH61_12240
NIB: GU926_18085
ADD: HUW48_10675
ASWU: HUW51_01025 HUW51_20485
MTT: Ftrac_1277 Ftrac_1374
MHAA: Q3Y49_01250 Q3Y49_18410
FPF: DCC35_20270
CLIT: OQ292_20050
IRO: RT717_15385 RT717_20555 RT717_21990
FBT: D770_01380 D770_10140 D770_22385
CHRW: KA713_17535
CHK: D4L85_06785 D4L85_13615 D4L85_30080
FUV: JR347_07595 JR347_12655 JR347_15925
FMM: LVD15_04060 LVD15_13350 LVD15_26280 LVD15_26705
FUA: LVD17_02965 LVD17_14155 LVD17_17735 LVD17_26230
FLW: LVD16_07845 LVD16_11895 LVD16_25410
REK: N6H18_09105
RCG: N7E81_09120 N7E81_17880 N7E81_18455
PRHO: PZB74_19095
TPEL: P0M28_09140 P0M28_30060
RSR: T7867_08970
ATK: AUTU_29800 AUTU_45020
GFO: GFO_1576
GRL: LPB144_03720
GRS: C7S20_13800 C7S20_17135 C7S20_18515
FPS: FP0413
FPC: FPSM_00450
FPY: FPG101_02255
FPO: FPG3_02170
FPQ: IB65_01940
FPV: IA03_02025
FPW: IA04_01965
FPK: IA06_02005
FPSZ: AMR72_11020 AMR72_12580
FJO: Fjoh_1748 Fjoh_4604
FJG: BB050_00859(desA3_1) BB050_02987(desA3_2)
FBR: FBFL15_0640
FCO: FCOL_03090
FIN: KQS_11875
FGL: EM308_06050 EM308_06795
FCM: BIW12_09460
FFA: FFWV33_01325
FAT: DVK85_08110
FKI: FK004_01385
FPAL: HYN49_01635
FMG: HYN48_01600
FALB: HYN59_06915
FCR: HYN56_07485 HYN56_09200 HYN56_22190
FSE: DI487_00875 DI487_09345
FSN: GS03_00241
FNK: E1750_13170
FAK: FUA48_01500
FFL: HYN86_08210 HYN86_18615
FEN: J0383_06845 J0383_08685 J0383_18340
FCV: AWN65_01780
FOE: JJC03_07225
FSD: LXD69_02525
FLO: K1I41_01625
FCC: LOS86_02380
FCB: LOS89_10880
FPB: NLJ00_09245 NLJ00_22200
FEH: LZF87_01210
FAZ: M0M57_04100
FBI: L0669_09080 L0669_20585
FCS: TRV642_1801
FAO: SHINM13_01670
FAN: GENT5_01820
FPLU: NLG42_08485 NLG42_21180
FHU: M0M44_09045 M0M44_21335
FCU: NOX80_01095
FPEC: Q1W71_02660 Q1W71_21030
FOK: KK2020170_03000
RBI: RB2501_02670
ZPR: ZPR_0940 ZPR_1492
CAT: CA2559_07355
FBC: FB2170_16751
MARM: YQ22_03825
MART: BTR34_03930
MARB: CJ263_13770
MARE: EJ994_00970
MLIO: NYZ99_14280
CAO: Celal_2252
CLY: Celly_0637
CLH: IX49_02930
CBAL: M667_08640
CBAT: M666_08605
COMN: PBN93_03195
KDI: Krodi_1870
DOK: MED134_12621
DDO: I597_1302(desA3)
DOD: DCS32_02495
LAN: Lacal_0517
LVN: BWR22_13235
LACI: CW733_04270 CW733_09735
ZGA: ZOBELLIA_1067(des6-2) ZOBELLIA_755(des6-1)
ZLA: Q5W13_03625
ASL: Aeqsu_0518
AEV: EI546_14540
AIC: JK629_01570 JK629_12490
PTQ: P700755_002699
PSYD: IMZ30_02630
POM: MED152_06405
POB: LPB03_14685
PRN: BW723_00980
POLA: BXQ17_06895
POA: CW731_14315
PHAL: H9I45_13935
PLIT: K8354_11165
PPEC: H9W90_09185
PBAT: JL193_04995
PCEA: J3359_15260
PUN: NQP51_15885
PHG: KCTC32516_00465(desA3)
WIN: WPG_2001
WIJ: BWZ20_06125
SZE: AW14_08200
AHZ: APS56_08280
SYI: SB49_00400
TDI: AUW17_12185
TEN: LPB136_09710
TJE: TJEJU_3739
TMAR: MARIT_2781
TMP: F9Y86_06280
TOV: PG911_17440
TRT: PG912_01315
TPAC: PG913_11730
TFI: PJJ26_12910
TTG: P8625_12730
TSIG: D6T69_04030
LUT: Lupro_06980
LUL: LPB138_09110
WFU: AXE80_00775
FOR: FORMB_06270
FOH: FORMA_06960
FOP: FNB79_06940
SALT: AO058_00115
SMIS: LDL76_09110
SEON: BWZ22_11950 BWZ22_15155
AALG: AREALGSMS7_02543(desA3)
OLL: CW732_06150
OAQ: DZC78_12695
FEK: C1H87_06880
FAY: Q4Q34_02805
TAJ: C1A40_11340
AUE: C5O00_08760
MARF: CJ739_552
AQB: D1818_09380 D1818_09485 D1818_09490
AQA: D1815_21665 D1815_21670 D1815_21765
AQD: D1816_10945
AQE: NBT05_08765
EMAR: D1013_05915 D1013_15030
MUR: EQY75_02165
PSYN: E9099_04030
PPON: MUN68_013590
AFLA: FHG64_13475
ANP: FK178_00105
OCI: FEZ18_11675
MGEL: G5B37_12950
MESQ: C7H62_0634
GAA: HX109_09955
CAGG: HYG79_02970
MARX: INR76_01415
LPAL: LDL79_12280
SINH: LS482_08330 LS482_12605
ASAG: FGM00_02900
FLG: LV716_02865
FLB: LV704_03710
MRS: Murru_0575 Murru_2048
MLT: VC82_2131
MUT: GVT53_01095
MAQI: LDL77_10735 LDL77_12845
SPON: HME9304_02346
SABU: MBM09_05465
ZSP: MQE36_09485
BIA: GMA17_04560 GMA17_09985
FBE: FF125_11040 FF125_18070
FBM: MQE35_03580
SAHN: JRG66_03265
ALUT: O5O44_13390
LUY: QZH61_13390
AEST: RBH94_09470
MANG: RBH95_14805
HWS: RNZ46_09970
FBQ: D1817_13600
EAO: BD94_3599
EMN: M876_15070
EEN: BBD30_08675
ELB: VO54_03046
EMG: BBD33_05475
EGM: AYC65_19675
ELZ: FCS00_12860
ELIZ: JCR23_12755
CHZ: CHSO_0007
CGN: OK18_10425
CIH: ATE47_14660
CIO: CEQ15_20755
CPIP: CJF12_09160 CJF12_11850
CARH: EGY05_00090 EGY05_16690
CSHA: EG350_17865
CNK: EG343_16780
CJT: EG359_17215
CIL: EG358_03810
CBEN: EG339_08225
CGLE: NCTC11432_03868
CTAI: NCTC12078_01616
CLAC: EG342_08295
CTAK: 4412677_01961
CNP: M0D58_13535
CCAO: H5J24_19795
CRHI: KB553_18450
CCAB: PFY12_11545
CHRJ: CHRYMOREF3P_3431
CORA: N0B40_13105
CFLU: ODZ84_16640
CIV: IMZ16_00065
FTE: Fluta_0285 Fluta_0832 Fluta_1718 Fluta_4072
FLU: CHH17_00735 CHH17_06930 CHH17_10485 CHH17_16625
CRM: K6119_02165 K6119_02195 K6119_18185
OHO: Oweho_1245 Oweho_2759
CHYD: H4K34_06255
PTAN: CRYO30217_01395
BBAU: AEM51_07385 AEM51_12040
SRG: XF24_00844(desA3)
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Reference
PMID:8389613
  Authors
Reddy AS, Nuccio ML, Gross LM, Thomas TL
  Title
Isolation of a delta 6-desaturase gene from the cyanobacterium Synechocystis sp. strain PCC 6803 by gain-of-function expression in Anabaena sp. strain PCC 7120.
  Journal
Plant Mol Biol 22:293-300 (1993)
DOI:10.1007/BF00014936
  Sequence
[syn:sll0262]
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