KEGG ORTHOLOGY: K01517

ORTHOLOGY: K01517

Entry

K01517                      KO

Symbol

ADPRM

Name

manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53]

Pathway

map00230

Purine metabolism

map00564

Glycerophospholipid metabolism

map01100

Metabolic pathways

Reaction

R00855

CDPglycerol phosphoglycerohydrolase

R01054

ADP-ribose ribophosphohydrolase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    K01517  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K01517  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
Enzymes [BR:ko01000]
3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.13  ADP-ribose diphosphatase
     K01517  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
    3.6.1.16  CDP-glycerol diphosphatase
     K01517  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
    3.6.1.53  Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase
     K01517  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase

Other DBs

GO:	0047631 0047734

Genes

HSA:	56985(ADPRM)

PTR:	745728(ADPRM)

PPS:	100989248(ADPRM)

GGO:	101139187(ADPRM)

PON:	100436862(ADPRM)

NLE:	100601662(ADPRM)

HMH:	116458238(ADPRM)

MCC:	717991(ADPRM)

MCF:	102147209(ADPRM)

MTHB:

126939727

MNI:	105473567(ADPRM)

CSAB:

103242388(ADPRM)

CATY:

105581448(ADPRM)

PANU:

101011738(ADPRM)

TGE:	112609623(ADPRM)

MLEU:

105534449(ADPRM)

RRO:	104675129(ADPRM)

RBB:	108520319(ADPRM)

TFN:	117067688(ADPRM)

PTEH:

111525452(ADPRM)

CANG:

105505425(ADPRM)

CJC:	100399298(ADPRM)

SBQ:	101035686(ADPRM)

CIMI:

108306475(ADPRM)

CSYR:

103252151(ADPRM)

MMUR:

105878313(ADPRM)

LCAT:

123650626(ADPRM)

PCOQ:

105818078(ADPRM)

OGA:	100947880(ADPRM)

MMU:	66358(Adprm)

MCAL:

110305174(Adprm)

MPAH:

110332174(Adprm)

RNO:	287406(Adprm)

MCOC:

116077456(Adprm)

ANU:	117710164(Adprm)

MUN:	110552777(Adprm)

CGE:	100767531(Adprm)

MAUA:

101825901(Adprm)

PROB:

127219115(Adprm)

PLEU:

114693125(Adprm)

MORG:

121456418(Adprm)

MFOT:

126513905

AAMP:

119812200(Adprm)

NGI:	103752060(Adprm)

HGL:	101700336(Adprm)

CPOC:

100728957 100735078

CCAN:

109697084(Adprm)

DORD:

105983501(Adprm)

DSP:	122117185(Adprm)

PLOP:

125366414(Adprm)

NCAR:

124979804

MMMA:

107158046(Adprm)

OCU:

100350105

OPI:	101531379(ADPRM)

TUP:	102478915(ADPRM)

GVR:	103601745(ADPRM)

CFA:	479504(ADPRM)

CLUD:

112647360(ADPRM)

VVP:	112924903(ADPRM)

VLG:	121499597(ADPRM)

NPO:	129496755(ADPRM)

AML:	100484618(ADPRM)

UMR:	103660405(ADPRM)

UAH:	113271215(ADPRM)

UAR:	123792077(ADPRM)

ELK:

111161136

LLV:

125087124

MPUF:

101676533(ADPRM)

MNP:	132003390(ADPRM)

MLK:	131815586(ADPRM)

NVS:	122906764(ADPRM)

ORO:	101374847(ADPRM)

EJU:	114225347(ADPRM)

ZCA:	113939129(ADPRM)

MLX:	118000074(ADPRM)

NSU:	110584604(ADPRM)

LWW:	102728358(ADPRM)

FCA:	101085161(ADPRM)

PYU:	121015893(ADPRM)

PCOO:

112857130(ADPRM)

PBG:	122484963(ADPRM)

PVIV:

125151528(ADPRM)

LRUF:

124519588

PTG:	102965979(ADPRM)

PPAD:

109245856(ADPRM)

PUC:

125926979

AJU:

106983330

HHV:	120231401(ADPRM)

BTA:	534038(ADPRM)

BOM:	102283155(ADPRM)

BIU:	109573878(ADPRM)

BBUB:

102391966(ADPRM)

BBIS:

104990713(ADPRM)

CHX:	102181988(ADPRM)

OAS:	101113772(ADPRM)

BTAX:

128065396(ADPRM)

ODA:	120865978(ADPRM)

CCAD:

122445103(ADPRM)

MBEZ:

129543887(ADPRM)

SSC:	100519388(ADPRM)

CFR:	102511144(ADPRM)

CBAI:

105077565(ADPRM)

CDK:	105095885(ADPRM)

VPC:	102542518(ADPRM)

BACU:

103010454(ADPRM)

BMUS:

118886740(ADPRM)

LVE:	103089607(ADPRM)

OOR:	101271746(ADPRM)

DLE:	111186014(ADPRM)

PCAD:

102975974(ADPRM)

PSIU:

116745527(ADPRM)

NASI:

112404783(ADPRM)

ECB:	100073085(ADPRM)

EPZ:	103557154(ADPRM)

EAI:	106845767(ADPRM)

MYB:	102260362(ADPRM)

MYD:	102759013(ADPRM) 102769086

MMYO:

118672158(ADPRM)

MLF:	102438238(ADPRM)

PKL:	118726904(ADPRM)

EFUS:

103296850(ADPRM)

MNA:	107544565(ADPRM)

DRO:	112308415(ADPRM)

SHON:

118974743(ADPRM)

AJM:	119056602(ADPRM)

PDIC:

114515391(ADPRM)

PHAS:

123809179(ADPRM)

MMF:	118634441(ADPRM)

PPAM:

129068804(ADPRM)

HAI:	109389128(ADPRM)

RFQ:	117012874(ADPRM)

PALE:

102882253(ADPRM)

PGIG:

120589741(ADPRM)

PVP:	105291270(ADPRM)

RAY:	107498319(ADPRM)

MJV:	108392721(ADPRM)

TOD:	119230843(ADPRM)

SARA:

101552793(ADPRM)

SETR:

126013730(ADPRM)

LAV:	100672645(ADPRM)

TMU:

101361939

ETF:	101652947(ADPRM)

DNM:	101447474(ADPRM)

MDO:	100031391(ADPRM)

GAS:	123245031(ADPRM)

SHR:	100918137(ADPRM)

AFZ:

127560735

PCW:	110193957(ADPRM)

OAA:	100089526(ADPRM)

GGA:	768578(ADPRM)

PCOC:

116235560(ADPRM)

MGP:	100544671(ADPRM)

CJO:	107321978(ADPRM)

TPAI:

128083180(ADPRM)

LMUT:

125702351(ADPRM)

NMEL:

110407346(ADPRM)

APLA:

101805114(ADPRM)

ACYG:

125184266(ADPRM)

CATA:

118255574(ADPRM)

AFUL:

116496663(ADPRM)

TGU:	100232304(ADPRM)

LSR:	110474918(ADPRM)

SCAN:

103823912(ADPRM)

PMOA:

120498260(ADPRM)

OTC:	121348142(ADPRM)

PRUF:

121352717(ADPRM)

GFR:	102037693(ADPRM)

FAB:	101822214(ADPRM)

OMA:	130260532(ADPRM)

PHI:	102102216(ADPRM)

PMAJ:

107212591(ADPRM)

CCAE:

111937534(ADPRM)

CCW:	104695677(ADPRM)

ETL:	114067596(ADPRM)

ZAB:	102068717(ADPRM)

ACHL:

103800792(ADPRM)

SVG:	106859511(ADPRM)

MMEA:

130588701(ADPRM)

HRT:	120760956(ADPRM)

FPG:	101917811(ADPRM)

FCH:	102046962(ADPRM)

CLV:	102096818(ADPRM)

NNI:	104014562(ADPRM)

PCRI:

104036996(ADPRM)

ACUN:

113490956(ADPRM)

TALA:

104358472(ADPRM)

PADL:

103925367(ADPRM)

AFOR:

103899677(ADPRM)

ACHC:

115342335(ADPRM)

HALD:

104311510(ADPRM)

HLE:	104839251(ADPRM)

AGEN:

126043993

GCL:

127024080

CCRI:

104155365(ADPRM)

CMAC:

104485420(ADPRM)

MUI:	104534111(ADPRM)

BREG:

104636056(ADPRM)

GSTE:

104251529(ADPRM)

SHAB:

115616520(ADPRM)

PGUU:

104458571(ADPRM)

ACAR:

104521012(ADPRM)

CPEA:

104398218(ADPRM)

RTD:	128917755(ADPRM)

CUCA:

104057895(ADPRM)

AAM:	106496876(ADPRM)

AROW:

112970885(ADPRM)

DNE:	112995542(ADPRM)

ASN:	102378502(ADPRM)

AMJ:	102564317(ADPRM)

CPOO:

109311086(ADPRM)

PSS:	102454910(ADPRM)

CMY:	102947863(ADPRM)

CCAY:

125621816(ADPRM)

DCC:	119842704(ADPRM)

CPIC:

101938771(ADPRM)

TST:	117887304(ADPRM)

CABI:

116838534(ADPRM)

MRV:	120383222(ADPRM)

ACS:	100557018(adprm)

ASAO:

132768542(ADPRM)

PVT:	110075038(ADPRM)

SUND:

121921434(ADPRM)

PBI:	103062440(ADPRM)

PMUR:

107282490(ADPRM)

CTIG:

120298329(ADPRM)

TSR:	106542940(ADPRM)

PGUT:

117660436(ADPRM)

APRI:

131192164(ADPRM)

PTEX:

113437211(ADPRM)

NSS:	113412138(ADPRM)

VKO:	123035487(ADPRM)

PMUA:

114590700(ADPRM)

PRAF:

128407580(ADPRM)

ZVI:	118079905(ADPRM)

HCG:	128343487(ADPRM)

STOW:

125428388(ADPRM)

EMC:	129329009(ADPRM)

XLA:	108701161(adprm.2.L) 380120(adprm.L)

XTR:	100498212(adprm.2) 493375(adprm)

NPR:	108800850 108801529(ADPRM)

RTEM:

120918990 120919145(ADPRM)

BBUF:

121004707(ADPRM) 121005235

BGAR:

122924105 122931349

MUO:	115473211 115473212

GSH:	117367400 117367401(ADPRM)

DRE:	393393(adprm)

SANH:

107653999(adprm)

SGH:	107556466(adprm)

CCAR:

109060013 109103884

CAUA:

113112013(adprm)

CGIB:

127969397

PTET:

122332670(adprm)

LROH:

127173755(adprm)

OMC:	131551042(adprm)

PPRM:

120464390(adprm)

RKG:	130096660(adprm)

MAMB:

125255884(adprm)

CIDE:

127523487

MASI:

127423156

TROS:

130569377(adprm)

TDW:	130439101(adprm)

MANU:

129421367(adprm)

IPU:

108274373

IFU:	128617428(adprm)

PHYP:

113527145(adprm)

SMEO:

124388762(adprm)

TFD:	113662614(adprm)

TVC:	132840043(adprm)

AMEX:

103043761 103044468

CMAO:

118809533(adprm)

EEE:	113570913(adprm)

CHAR:

122130802(adprm)

TNG:	GSTEN00021735G001

LCO:	104919483(adprm)

NCC:	104963227(adprm)

TBEN:

117483657(adprm)

CGOB:

115024397(adprm)

PGEO:

117439074(adprm)

GACU:

117552372(adprm)

EMAC:

134871299(adprm)

ELY:	117246741(adprm)

EFO:	125881206(adprm)

PLEP:

121958470(adprm)

SLUC:

116067530(adprm)

ECRA:

117936605(adprm)

ESP:	116671101 116705659

PFLV:

114548639(adprm)

GAT:	120819488(adprm)

PPUG:

119212515(adprm)

AFB:	129093505(adprm)

CLUM:

117749227(adprm)

PSWI:

130203214(adprm)

MSAM:

119894653 119916291(adprm)

SCHU:

122867153(adprm)

CUD:	121527869(adprm)

ALAT:

119009365(adprm)

MZE:	101478096(adprm)

ONL:	100710111(adprm)

OAU:	116330879(adprm)

OLA:	105356600 111946384

OML:	112153871(adprm)

CSAI:

133419514(adprm)

XMA:	102227889(adprm)

XCO:	114151735(adprm)

XHE:	116726664(adprm)

PRET:

103481918(adprm)

PFOR:

103144496(adprm)

PLAI:

106964992(adprm)

PMEI:

106924853(adprm)

GAF:	122823157(adprm)

PPRL:

129377466(adprm)

CVG:	107096249(adprm)

CTUL:

119796022(adprm)

GMU:	124875574(adprm)

NFU:	107373834 107397354

KMR:	108235853(adprm)

ALIM:

106531924

NWH:	119423774(adprm)

AOCE:

111572502(adprm)

MCEP:

125022935(adprm)

CSEM:

103382417(adprm)

POV:	109643054(adprm)

SSEN:

122760971(adprm)

HHIP:

117753109(adprm)

HSP:	118101073(adprm)

SMAU:

118286965(adprm)

LCF:

108890898

SDU:	111219537(adprm)

SLAL:

111667088(adprm)

XGL:	120793977(adprm)

HCQ:	109512603(adprm)

SSCV:

125991608

SBIA:

133495550(adprm)

PEE:	133417958(adprm)

PTAO:

133468877(adprm)

BPEC:

110154055(adprm)

MALB:

109966666(adprm)

BSPL:

114845947(adprm)

SJO:	128381651(adprm)

SASA:

106589237(adprm)

STRU:

115201274(adprm)

OTW:	112233704(adprm)

OMY:	110498890(adprm)

OGO:	124040121(adprm)

ONE:	115144576(adprm)

OKI:	109870476(adprm)

OKE:	118402643(adprm)

SALP:

111967034(adprm)

SNH:	120029905(adprm)

CCLU:

121547983(adprm)

ELS:	105023010(adprm)

SFM:	108939934 114909203

PKI:	111856920(adprm)

AANG:

118220164(adprm)

LOC:	102683124(adprm)

PSPA:

121295923 121296479

ARUT:

117423255(adprm) 117424544

PSEX:

120517834(adprm)

LCM:	102354487(ADPRM)

CMK:	103175697(adprm)

RTP:	109912985 109912988

CPLA:

122562028(adprm) 122562029

HOC:	132827659(adprm) 132827660

LERI:

129708126(adprm)

BFO:

BBEL:

SCLV:

LPIC:

APLC:

AJC:

SKO:

DSV:

RSAN:

RMP:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

HRO:	HELRODRAFT_123984

LGI:	LOTGIDRAFT_149678

PVUL:

126811765

PCAN:

112566952

BGT:	106056255 106058336

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:	110448605 110448607 110448642

PMAX:

117331538 117331549 117331556

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

EPA:

ADF:

AMIL:

PDAM:

SPIS:

HMG:	100198316 100198467 105843075

HSY:

ATH:

ALY:

CRB:

CSAT:

104717803 104722510 104730974

EUS:	EUTSA_v10025788mg

BRP:

108868780

BNA:	111198213 111198217

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10021198mg

PVY:

116137190

MINC:

123211286

TCC:

18604977

GRA:	105764744 105788525

GHI:	107887289 107946572 107949731 121224249

GAB:	108483804 108486747

HSYR:

120122201 120155034 120155035

DZI:

111284677

EGR:

104417636

GMX:	100780293 100792911 100808714 100815255

GSJ:	114394051 114412007 114416398 114416400

PVU:	PHAVU_003G206000g PHAVU_009G172700g PHAVU_009G172800g PHAVU_009G172900g

VRA:	106753290 106761055 106761199 106761426

VAR:	108330242 108330655 108330910 108334577

VUN:	114162196 114162277 114164439 114177949

VUM:	124824375 124824376 124824378 124841351 124846211

CCAJ:

109791847 109797016

APRC:

113847274 113847696

MTR:	11416144 25493698

TPRA:

123884721 123898115

CAM:	101501360 101505685

PSAT:

127073983 127083725

VVO:	131636564 131656043

LJA:	Lj0g3v0335139.1(Lj0g3v0335139.1) Lj0g3v0335139.2(Lj0g3v0335139.2)

ADU:	107478909 107489578

AIP:	107629382 107631189

AHF:	112722265 112736302 112790435 112805522

LANG:

109328725 109362447 109362932

PCIN:

129320462

QSA:	O6P43_022644 O6P43_030818

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:

PEU:	105118923 105136717

PALZ:

JRE:

CILL:

CAVE:

QSU:

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107766620 107813486 107817197 107821971

NSY:	104218770 104242644

NTO:	104099242 104104495

NAU:	109208701 109239772

INI:

109180078

ITR:

116010271

SIND:

105157296 105179367

OEU:	111396293 111407625

EGT:	105950434 105975095

SSPL:

121754155 121758132 121761779 121763377 121763557 121789649 121789652

SMIL:

131005113 131019671 131019672

SHIS:

125200587 125212528 125223717

APAN:

127252867 127255344

HAN:	110879851 110879853 110879854

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:	130755831 130761416 130773301

BVG:

104884525

SOE:

110802382

CQI:	110687827 110715551

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

OSA:	4344352 4346295

DOSA:

Os07t0688000-01(Os07g0688000) Os08t0557200-01(Os08g0557200)

OBR:

102712498

OGL:	127779151 127781469

BDI:	100823930 100846848

ATS:	109779171 109779172 109782101

TDC:	119302974 119302975 119311650 119311651 119330944 119340739

TAES:

123104872 123104873 123113158 123113159 123122678 123122679 123152762 123161595 123169332

TUA:	125510473 125510475 125521051 125527443 125527445 125556628 125556630

LPER:

127303041 127316255

LRD:	124652517 124672775 124680375

SBI:	110433154 8057997

ZMA:	100191359 103653268

SITA:

101771143 101781539

SVS:	117846620 117860064

PVIR:

120659981 120671022 120679067 120713827

PHAI:

PDA:

EGU:

MUS:

ZOF:	121971410 121976251 122021109 122025701

DCT:

110114792

PEQ:	110018884 110024473

AOF:	109830064 109843108

MSIN:

131239852

NCOL:

116250524

ATR:

18442745

SMO:	SELMODRAFT_112495 SELMODRAFT_78013

PPP:	112276109 112292179

MNG:	MNEG_2546 MNEG_4962

CSL:	COCSUDRAFT_12655

CVR:	CHLNCDRAFT_138033 CHLNCDRAFT_36248

APRO:

F751_1456

OLU:	OSTLU_5767 OSTLU_5807

OTA:	OT_ostta01g03460 OT_ostta09g01710

BPG:	Bathy01g04470 Bathy10g02940

MIS:	MICPUN_60963 MICPUN_88004

MPP:	MICPUCDRAFT_5295(JGI:MicpuC2_5295) MICPUCDRAFT_58423(JGI:MicpuC2_58423)

CME:	CYME_CMQ308C

GSL:	Gasu_29190

CCP:	CHC_T00008291001 CHC_T00009409001

SMIN:

v1.2.028698.t1(symbB.v1.2.028698.t1)

FCY:	FRACYDRAFT_160037

TPS:	THAPSDRAFT_16656

PIF:	PITG_00701

PSOJ:

PHYSODRAFT_315792

SPAR:

SPRG_19962

EHX:	EMIHUDRAFT_239808 EMIHUDRAFT_55032

GTT:	GUITHDRAFT_135549

PBW:	D172_001300

PAGA:

PAGA_a0239

SPHK:

SKP52_05880

GRC:	GI584_05825

ARU:	ASPU41_17480

ARTH:

PBAS:

ALUS:

PFER:

BCAC:

MCOS:

CBAE:

SPDR:

POM:	MED152_12824

POB:	LPB03_06815

PRN:	BW723_00645

POLA:

BXQ17_06130

LUL:	LPB138_09200

» show all

Reference

PMID:18352857

Authors

Canales J, Fernandez A, Ribeiro JM, Cabezas A, Rodrigues JR, Cameselle JC, Costas MJ

Title

Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase: a novel metallophosphoesterase family preferentially expressed in rodent immune cells.

Journal

Biochem J 413:103-13 (2008)
DOI:10.1042/BJ20071471

Sequence

[rno:287406]

Reference

PMID:22848751

Authors

Rodrigues JR, Fernandez A, Canales J, Cabezas A, Ribeiro JM, Costas MJ, Cameselle JC

Title

Characterization of Danio rerio Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase, the structural prototype of the ADPRibase-Mn-like protein family.

Journal

PLoS One 7:e42249 (2012)
DOI:10.1371/journal.pone.0042249

Sequence

[dre:393393]

LinkDB

DBGET integrated database retrieval system