| Entry |
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| Symbol |
neuB, nnaB
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| Name |
N-acetylneuraminate synthase [EC: 2.5.1.56]
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| Pathway |
| map00520 | Amino sugar and nucleotide sugar metabolism |
| map00541 | O-Antigen nucleotide sugar biosynthesis |
| map01250 | Biosynthesis of nucleotide sugars |
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| Module |
| M00922 | CMP-Neu5Ac biosynthesis |
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| Reaction |
| R01804 | phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming) |
| R04435 | phosphoenolpyruvate:N-acetyl-D-mannosamine-6-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming) |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09101 Carbohydrate metabolism
00520 Amino sugar and nucleotide sugar metabolism
K01654 neuB, nnaB; N-acetylneuraminate synthase
09107 Glycan biosynthesis and metabolism
00541 O-Antigen nucleotide sugar biosynthesis
K01654 neuB, nnaB; N-acetylneuraminate synthase
Enzymes [BR:ko01000]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.56 N-acetylneuraminate synthase
K01654 neuB, nnaB; N-acetylneuraminate synthase
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| Other DBs |
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| Genes |
» show all
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| Reference |
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| Authors |
Sundaram AK, Pitts L, Muhammad K, Wu J, Betenbaugh M, Woodard RW, Vann WF |
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| Title |
Characterization of N-acetylneuraminic acid synthase isoenzyme 1 from Campylobacter jejuni. |
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| Journal |
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| Reference |
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| Authors |
Suryanti V, Nelson A, Berry A |
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| Title |
Cloning, over-expression, purification, and characterisation of N-acetylneuraminate synthase from Streptococcus agalactiae. |
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| Journal |
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| Reference |
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| Authors |
Lewis AL, Robinson LS, Agarwal K, Lewis WG |
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| Title |
Discovery and characterization of de novo sialic acid biosynthesis in the phylum Fusobacterium. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Feng L, Senchenkova SN, Tao J, Shashkov AS, Liu B, Shevelev SD, Reeves PR, Xu J, Knirel YA, Wang L |
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| Title |
Structural and genetic characterization of enterohemorrhagic Escherichia coli O145 O antigen and development of an O145 serogroup-specific PCR assay. |
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| Journal |
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| LinkDB |
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