 | | ORTHOLOGY: K01737 | |
| Entry |
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| Symbol |
queD, ptpS, PTS
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| Name |
6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC: 4.2.3.12 4.1.2.50]
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| Pathway |
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| Module |
| M00842 | Tetrahydrobiopterin biosynthesis, GTP => BH4 |
| M00843 | L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4 |
| M00988 | PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine |
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| Reaction |
| R04286 | 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate lyase |
| R09959 | 7,8-dihydroneopterin 3'-triphosphate acetaldehyde-lyase (6-carboxy-5,6,7,8-tetrahydropterin and triphosphate-forming) |
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| Disease |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
K01737 queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03016 Transfer RNA biogenesis
K01737 queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase
Enzymes [BR:ko01000]
4. Lyases
4.1 Carbon-carbon lyases
4.1.2 Aldehyde-lyases
4.1.2.50 6-carboxytetrahydropterin synthase
K01737 queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase
4.2 Carbon-oxygen lyases
4.2.3 Acting on phosphates
4.2.3.12 6-pyruvoyltetrahydropterin synthase
K01737 queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase
Transfer RNA biogenesis [BR:ko03016]
Prokaryotic type
tRNA modification factors
Other tRNA modification factors
K01737 queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase
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| Other DBs |
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| Genes |
» show all
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| Reference |
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| Authors |
Lee SW, Lee HW, Chung HJ, Kim YA, Kim YJ, Hahn Y, Chung JH, Park YS |
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| Title |
Identification of the genes encoding enzymes involved in the early biosynthetic pathway of pteridines in Synechocystis sp. PCC 6803. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
McCarty RM, Somogyi A, Lin G, Jacobsen NE, Bandarian V |
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| Title |
The deazapurine biosynthetic pathway revealed: in vitro enzymatic synthesis of PreQ(0) from guanosine 5'-triphosphate in four steps. |
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| Journal |
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| LinkDB |
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