KEGG   ORTHOLOGY: K03391
Entry
K03391            Tight     KO                                     
Symbol
pcpB
Name
pentachlorophenol monooxygenase [EC:1.14.13.50]
Pathway
map00361  Chlorocyclohexane and chlorobenzene degradation
map00364  Fluorobenzoate degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Reaction
R03982  pentachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating, dechloronating)
R07779  bromoxynil,NADPH:oxygen oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00364 Fluorobenzoate degradation
    K03391  pcpB; pentachlorophenol monooxygenase
   00361 Chlorocyclohexane and chlorobenzene degradation
    K03391  pcpB; pentachlorophenol monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.50  pentachlorophenol monooxygenase
     K03391  pcpB; pentachlorophenol monooxygenase
Other DBs
COG: COG0654
GO: 0018677
Genes
SCH: Sphch_3461
Reference
PMID:12169590
  Authors
Cai M, Xun L
  Title
Organization and regulation of pentachlorophenol-degrading genes in Sphingobium chlorophenolicum ATCC 39723.
  Journal
J Bacteriol 184:4672-80 (2002)
DOI:10.1128/JB.184.17.4672-4680.2002
  Sequence
[sch:Sphch_3461]
Reference
PMID:23676275
  Authors
Yadid I, Rudolph J, Hlouchova K, Copley SD
  Title
Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol.
  Journal
Proc Natl Acad Sci U S A 110:E2182-90 (2013)
DOI:10.1073/pnas.1214052110
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