KEGG ORTHOLOGY: K03987

ORTHOLOGY: K03987

Entry

K03987                      KO

Symbol

C1QB

Name

complement C1q subcomponent subunit B

Pathway

map04148

Efferocytosis

map04610

Complement and coagulation cascades

map04936

Alcoholic liver disease

map05020

Prion disease

map05133

Pertussis

map05142

Chagas disease

map05150

Staphylococcus aureus infection

map05171

Coronavirus disease - COVID-19

map05322

Systemic lupus erythematosus

Disease

H00102

Classic complement pathway component defects

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    K03987  C1QB; complement C1q subcomponent subunit B
09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K03987  C1QB; complement C1q subcomponent subunit B
09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K03987  C1QB; complement C1q subcomponent subunit B
  09171 Infectious disease: bacterial
   05133 Pertussis
    K03987  C1QB; complement C1q subcomponent subunit B
   05150 Staphylococcus aureus infection
    K03987  C1QB; complement C1q subcomponent subunit B
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K03987  C1QB; complement C1q subcomponent subunit B
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K03987  C1QB; complement C1q subcomponent subunit B
  09164 Neurodegenerative disease
   05020 Prion disease
    K03987  C1QB; complement C1q subcomponent subunit B
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K03987  C1QB; complement C1q subcomponent subunit B
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K03987  C1QB; complement C1q subcomponent subunit B
Membrane trafficking [BR:ko04131]
Endocytosis
  Phagocytosis
   Opsonins
    K03987  C1QB; complement C1q subcomponent subunit B

Other DBs

GO:

0005602

Genes

HSA:

713(C1QB)

PTR:	469214(C1QB)

PPS:	100994127(C1QB)

GGO:	101124764(C1QB)

PON:	100435212(C1QB)

NLE:	100607840(C1QB)

HMH:	116813046(C1QB)

MCC:	718307(C1QB)

MCF:	102139434(C1QB)

MTHB:

126955793

MNI:	105494407(C1QB)

CSAB:

103225408(C1QB)

CATY:

105595016(C1QB)

PANU:

116274504(C1QB)

TGE:	112609134(C1QB)

MLEU:

105529433(C1QB)

RRO:	104663227(C1QB)

RBB:	108538439(C1QB)

TFN:	117093154(C1QB)

PTEH:

111547712(C1QB)

CANG:

105514278(C1QB)

CJC:	100405501(C1QB)

SBQ:	101049399(C1QB)

CIMI:

108308624(C1QB)

CSYR:

103260015(C1QB)

MMUR:

105873604

LCAT:

123634443(C1QB)

PCOQ:

105815704(C1QB)

MMU:	12260(C1qb)

MCAL:

110292976(C1qb)

MPAH:

110323604(C1qb)

RNO:	29687(C1qb)

MCOC:

116095787(C1qb)

ANU:	117708169(C1qb)

MUN:	110545384(C1qb)

CGE:	100766700(C1qb)

MAUA:

101825252(C1qb)

PROB:

127213266(C1qb)

PLEU:

114697212(C1qb)

MORG:

121448477(C1qb)

MFOT:

126509872

AAMP:

119816913(C1qb)

NGI:	103746400(C1qb)

HGL:	101704691(C1qb)

CPOC:

100715803(C1qb)

DORD:

106000031(C1qb)

DSP:	122115202(C1qb)

PLOP:

125354696(C1qb)

NCAR:

124981820

MMMA:

107142148(C1qb)

OCU:

127482788

OPI:	101516369(C1QB)

TUP:	102492509(C1QB)

GVR:	103590523(C1QB)

CFA:	487381(C1QB)

CLUD:

112660280(C1QB)

VVP:	112930158(C1QB)

VLG:	121496501(C1QB)

NPO:	129513819(C1QB)

AML:	100466574(C1QB)

UAH:	113268536(C1QB)

UAR:	123782228(C1QB)

LLV:

125098971

MNP:	132001747(C1QB)

MLK:	131809706(C1QB)

NVS:	122898609(C1QB)

ORO:	101372635(C1QB)

ZCA:	113916266(C1QB)

MLX:	118019908(C1QB)

NSU:	123324554(C1QB)

LWW:	102732686(C1QB)

FCA:	101096331(C1QB)

PCOO:

112862213(C1QB)

PBG:	122480075(C1QB)

PVIV:

125173889(C1QB)

PTG:	102972468(C1QB)

PPAD:

109274283(C1QB)

PUC:

125912983

HHV:	120230960(C1QB)

BTA:	617435(C1QB)

BOM:	102264986(C1QB)

BIU:	109574037(C1QB)

BBUB:

102405769(C1QB)

BBIS:

104981094(C1QB)

CHX:	102186813(C1QB)

OAS:	121818782(C1QB)

BTAX:

128043404(C1QB)

ODA:	120855022(C1QB)

CCAD:

122426674(C1QB)

MBEZ:

129538397(C1QB)

SSC:	100518846(C1QB)

CFR:	116668289(C1QB)

CBAI:

105070868(C1QB)

CDK:	105088875(C1QB)

VPC:	102532306(C1QB)

BACU:

103011614(C1QB)

LVE:	103086274(C1QB)

DLE:	111163327(C1QB)

PCAD:

102978873(C1QB)

PSIU:

116744455(C1QB)

NASI:

112414446(C1QB)

ECB:	100071667(C1QB)

EPZ:	103541871(C1QB)

EAI:	106839997(C1QB)

MYB:	102255230(C1QB)

MYD:	102756834(C1QB)

MMYO:

118677075(C1QB)

MLF:	102440713(C1QB)

PKL:	118722482(C1QB)

EFUS:

103291966(C1QB)

MNA:	107538377(C1QB)

DRO:	112299478(C1QB)

AJM:	119042178(C1QB)

PDIC:

114497365(C1QB)

MMF:	118626897(C1QB)

PPAM:

129069156(C1QB)

HAI:	109396733(C1QB)

RFQ:	117027629(C1QB)

PALE:

102887385(C1QB)

PGIG:

120596101(C1QB)

PVP:	105290439(C1QB)

RAY:	107513063(C1QB)

MJV:	108407308(C1QB)

TOD:	119236254(C1QB)

SARA:

101541586(C1QB)

SETR:

126011266(C1QB)

LAV:	100663347(C1QB)

TMU:

101348685

ETF:	101638471(C1QB)

DNM:	101437063(C1QB)

MDO:	100029312(C1QB)

GAS:	123243136(C1QB)

PCW:	110206039(C1QB)

OAA:	114812254(C1QB)

GGA:	428197(C1QB)

MGP:	100546619(C1QB)

CJO:	107323571(C1QB)

TPAI:

128085041(C1QB)

LMUT:

125703452(C1QB)

NMEL:

110408713(C1QB)

APLA:

101803105(C1QB)

ACYG:

106040156(C1QB)

CATA:

118253406(C1QB)

AFUL:

116497633(C1QB)

TGU:	100223187(C1QB)

LSR:	110472265(C1QB)

SCAN:

103824164(C1QB)

PMOA:

120498987(C1QB)

OTC:	121333078(C1QB)

PRUF:

121351393(C1QB)

GFR:	102035536(C1QB)

FAB:	101807280(C1QB)

OMA:	130261738(C1QB)

PHI:	102105506(C1QB)

PMAJ:

107213705(C1QB)

CCAE:

111938538(C1QB)

CCW:	104697576(C1QB)

CBRC:

103616183(C1QB)

ETL:	114070039(C1QB)

ZLE:	135456590(C1QB)

ACHL:

103808848(C1QB)

SVG:	106856375(C1QB)

MMEA:

130582498(C1QB)

HRT:	120762297(C1QB)

FPG:	101922426(C1QB)

FCH:	102049289(C1QB)

CLV:	106145645(C1QB)

EGZ:	104131867(C1QB)

NNI:	104011205(C1QB)

PCRI:

104031495(C1QB)

PLET:

104624604(C1QB)

EHS:	104508731(C1QB)

PCAO:

104047019(C1QB)

ACUN:

113487920(C1QB)

TALA:

104363879(C1QB)

PADL:

103925403(C1QB)

AFOR:

103906990(C1QB)

ACHC:

115343013(C1QB)

HALD:

104313963(C1QB)

HLE:	104837803(C1QB)

AGEN:

126037689

GCL:

127024671

CCRI:

104158864(C1QB)

CSTI:

104552631(C1QB)

CMAC:

104486790(C1QB)

MUI:	104544398(C1QB)

BREG:

104641930(C1QB)

FGA:	104082016(C1QB)

GSTE:

104257335(C1QB)

LDI:	104348905(C1QB)

MNB:	103771113(C1QB)

OHA:	104332994(C1QB)

NNT:

104404764

SHAB:

115617397(C1QB)

PGUU:

104462408(C1QB)

ACAR:

104522324(C1QB)

AVIT:

104272103(C1QB)

CVF:	104290699(C1QB)

RTD:	128918493(C1QB)

CUCA:

104060765(C1QB)

TEO:	104371590(C1QB)

BRHI:

104497899(C1QB)

AAM:	106496016(C1QB)

AROW:

112966876(C1QB)

NPD:	112957389(C1QB)

TGT:	104578646(C1QB)

DNE:	112988471(C1QB)

SCAM:

104153645(C1QB)

ASN:	102376788(C1QB)

CPOO:

109314280(C1QB)

GGN:	109293885(C1QB)

PSS:

102446475

CMY:	102940493(C1QB)

DCC:	119845071(C1QB)

CPIC:

101942579(C1QB)

TST:	117867872(C1QB)

CABI:

116829029(C1QB)

MRV:	120388052(C1QB)

ASAO:

132764659(C1QB)

PVT:	110089371(C1QB)

SUND:

121936686(C1QB)

PBI:	103067397(C1QB)

PMUR:

107284659(C1QB)

CTIG:

120319120(C1QB)

TSR:

106540987

PGUT:

117657666

APRI:

131187173

PTEX:

113450788(C1QB)

NSS:	113430766(C1QB)

VKO:	123034753(C1QB)

PMUA:

114602587(C1QB)

PRAF:

128419647(C1QB)

ZVI:	118086993(C1QB)

HCG:	128338729(C1QB)

GJA:	107121465 107124992

STOW:

125445785(C1QB)

EMC:	129344662(C1QB)

XLA:	444263(c1qb.L)

XTR:

116408190

NPR:	108804086(C1QB)

RTEM:

120921969

BBUF:

120995031(C1QB)

BGAR:

122927029(C1QB)

MUO:	115482560(C1QB)

GSH:	117349229(C1QB)

SRX:

SANH:

SGH:

CAUA:

IFU:	128622349(c1qb)

AMEX:

103024341(c1qb)

TRU:

101062052

TFS:	130524474(c1qb)

LCO:

NCC:

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:

EFO:	125889173(c1qb)

PLEP:

121937684 121950809(c1qb)

SLUC:

116053789(c1qb)

ECRA:

PFLV:

GAT:

PPUG:

AFB:

CLUM:

MSAM:

119885791(c1qb)

SCHU:

122882625

CUD:	121529413(c1qb)

ALAT:

119021945(c1qb)

MZE:

ONL:

OAU:

OLA:

OML:

CSAI:

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

GMU:	124856279(c1qb)

KMR:	108249501(c1qb)

ALIM:

106529098

NWH:

119412731

MCEP:

125006145(c1qb)

POV:

109635432

SSEN:

122767721

HHIP:

117761933(c1qb)

HSP:	118105377(c1qb)

PPLT:

SMAU:

SDU:

SLAL:

XGL:	120806923(c1qb)

MALB:

109966384

BSPL:

114855989

SJO:

128355199

SASA:

100380615(c1qb)

STRU:

115204701

OTW:	112246338 121841648(c1qb)

OMY:	110510313(c1qb)

OGO:

124023205

OKI:

109873937

OKE:	127928742(c1qb)

SNH:	120042227(c1qb)

CCLU:

121558446

SFM:

108924692

PKI:

111838022

AANG:

118235610(c1qb)

ARUT:

117397237 117966684

LCM:	106705089(C1QB)

RTP:

CPLA:

HOC:

LERI:

APLC:

MMER:

RPHI:

Reference

PMID:15709773

Authors

Tissot B, Gonnet F, Iborra A, Berthou C, Thielens N, Arlaud GJ, Daniel R

Title

Mass spectrometry analysis of the oligomeric C1q protein reveals the B chain as the target of trypsin cleavage and interaction with fucoidan.

Journal

Biochemistry 44:2602-9 (2005)
DOI:10.1021/bi047802h

Sequence

[hsa:713]

Reference

PMID:3000358

Authors

Reid KB

Title

Molecular cloning and characterization of the complementary DNA and gene coding for the B-chain of subcomponent C1q of the human complement system.

Journal

Biochem J 231:729-35 (1985)
DOI:10.1042/bj2310729

Sequence

[hsa:713]

LinkDB

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