KEGG ORTHOLOGY: K04237

ORTHOLOGY: K04237

Entry

K04237                      KO

Symbol

PARD3

Name

partitioning defective protein 3

Pathway

map04015

Rap1 signaling pathway

map04062

Chemokine signaling pathway

map04144

Endocytosis

map04360

Axon guidance

map04390

Hippo signaling pathway

map04391

Hippo signaling pathway - fly

map04520

Adherens junction

map04530

Tight junction

map05165

Human papillomavirus infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K04237  PARD3; partitioning defective protein 3
   04390 Hippo signaling pathway
    K04237  PARD3; partitioning defective protein 3
   04391 Hippo signaling pathway - fly
    K04237  PARD3; partitioning defective protein 3
09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K04237  PARD3; partitioning defective protein 3
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K04237  PARD3; partitioning defective protein 3
   04530 Tight junction
    K04237  PARD3; partitioning defective protein 3
09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    K04237  PARD3; partitioning defective protein 3
  09158 Development and regeneration
   04360 Axon guidance
    K04237  PARD3; partitioning defective protein 3
09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K04237  PARD3; partitioning defective protein 3
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04237  PARD3; partitioning defective protein 3
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04237  PARD3; partitioning defective protein 3

Genes

HSA:	56288(PARD3)

PTR:	450398(PARD3)

PPS:	100990710(PARD3)

GGO:	101145854(PARD3)

PON:	100431669(PARD3)

NLE:	100592712(PARD3)

HMH:	116461752(PARD3)

MCC:	706472(PARD3)

MCF:	102114934(PARD3)

MTHB:

126962979

MNI:	105495968(PARD3)

CSAB:

103238107(PARD3)

CATY:

105597005(PARD3)

PANU:

101007578(PARD3)

TGE:	112631241(PARD3)

RRO:	104661201(PARD3)

RBB:	108529253(PARD3)

TFN:	117082638(PARD3)

PTEH:

111546665(PARD3)

CANG:

105521843(PARD3)

CJC:	100393064(PARD3)

SBQ:	101039526(PARD3)

CIMI:

108309185(PARD3)

CSYR:

103268248(PARD3)

MMUR:

105871976(PARD3)

LCAT:

123626590(PARD3)

PCOQ:

105808527(PARD3)

OGA:	100949549(PARD3)

MMU:	93742(Pard3)

MCAL:

110300435(Pard3)

MPAH:

110337655(Pard3)

RNO:	81918(Pard3)

MCOC:

116070446(Pard3)

ANU:	117722857(Pard3)

MUN:	110554854(Pard3)

CGE:	100765823(Pard3)

MAUA:

101831084(Pard3)

PROB:

127234598(Pard3)

PLEU:

114705775(Pard3)

MORG:

121446866(Pard3)

MFOT:

126504718

AAMP:

119802077(Pard3)

NGI:	103745649(Pard3)

HGL:	101705735(Pard3) 101709720

CPOC:

100721421(Pard3)

CCAN:

109684712 109684714

DORD:

105980492(Pard3)

DSP:	122113067(Pard3)

PLOP:

125367288(Pard3)

NCAR:

124962289

MMMA:

107140411(Pard3)

OCU:

100345030

OPI:	101534140(PARD3)

TUP:	102493456(PARD3)

GVR:	103587257(PARD3)

CFA:	477953(PARD3)

CLUD:

112679010(PARD3)

VVP:	112921564(PARD3)

VLG:	121496593(PARD3)

NPO:	129499040(PARD3)

AML:	100473914(PARD3)

UMR:	103656515(PARD3)

UAH:	113244227(PARD3)

UAR:	123784872(PARD3)

ELK:

111155563

LLV:

125106409

MPUF:

101687218(PARD3)

MNP:	132020202(PARD3)

MLK:	131838311(PARD3)

NVS:	122892009(PARD3)

ORO:	101375042(PARD3)

EJU:	114222404(PARD3)

ZCA:	113921708(PARD3)

MLX:	118026623(PARD3)

NSU:	110576796(PARD3)

LWW:

102733787

FCA:	101100223(PARD3)

PYU:	121014621(PARD3)

PCOO:

112867938(PARD3)

PBG:	122473270(PARD3)

PVIV:

125169973(PARD3)

LRUF:

124501833

PTG:	102949054(PARD3)

PPAD:

109276301(PARD3)

PUC:

125920035

AJU:

106967346

HHV:	120247429(PARD3)

BTA:	527964(PARD3)

BOM:	102276028(PARD3)

BIU:	109567918(PARD3)

BBUB:

102400131(PARD3)

BBIS:

105002984(PARD3)

CHX:	102185098(PARD3)

OAS:	101110782(PARD3)

BTAX:

128058577(PARD3)

ODA:	120869241(PARD3)

CCAD:

122448866(PARD3) 122451294

MBEZ:

129557434(PARD3)

SSC:	100512009(PARD3)

CFR:

102507360

CBAI:

105072482(PARD3)

CDK:

105099564

VPC:	102526571(PARD3)

BACU:

103004935(PARD3)

BMUS:

118889999(PARD3)

LVE:	103072473(PARD3)

OOR:	101280921(PARD3)

DLE:	111178033(PARD3)

PCAD:

102990471(PARD3)

PSIU:

116748687(PARD3)

NASI:

112413880(PARD3)

ECB:	100060218(PARD3)

EPZ:	103555589(PARD3)

EAI:	106836623(PARD3)

MYB:	102256516(PARD3)

MYD:	102758013(PARD3)

MMYO:

118676463(PARD3)

MLF:	102440360(PARD3)

PKL:	118728003(PARD3)

EFUS:

103299446(PARD3)

MNA:	107525082(PARD3)

DRO:	112317737(PARD3)

SHON:

118982724(PARD3)

AJM:	119038847(PARD3)

PDIC:

114492546(PARD3)

PHAS:

123806690(PARD3)

MMF:	118616553(PARD3)

PPAM:

129077765(PARD3)

HAI:	109388150(PARD3)

RFQ:	117022147(PARD3)

PALE:

102898497(PARD3)

PGIG:

120584128(PARD3)

PVP:	105303015(PARD3)

RAY:	107520741(PARD3)

TOD:	119244151(PARD3)

SARA:

101553504(PARD3)

SETR:

126013353(PARD3)

LAV:	100662336(PARD3)

TMU:

101355481

ETF:	101653959(PARD3)

DNM:	101422709(PARD3)

MDO:	100022889(PARD3)

GAS:	123248808(PARD3)

SHR:	100914747(PARD3)

AFZ:

127564166

PCW:	110211239(PARD3)

OAA:	100077371(PARD3)

GGA:	420468(PARD3)

PCOC:

116244385(PARD3)

CJO:	107308917(PARD3)

TPAI:

128085451(PARD3)

LMUT:

125696452(PARD3)

NMEL:

110395113(PARD3)

APLA:

101792870(PARD3)

ACYG:

106045295(PARD3)

CATA:

118247371(PARD3)

AFUL:

116486774(PARD3)

TGU:	100217481(PARD3)

LSR:	110477302(PARD3)

SCAN:

103813075(PARD3)

PMOA:

120500652(PARD3)

OTC:	121338048(PARD3)

PRUF:

121364306(PARD3)

GFR:	102040324(PARD3)

FAB:	101810096(PARD3)

OMA:	130249074(PARD3)

PHI:	102111133(PARD3)

PMAJ:

107200007(PARD3)

CCAE:

111924082(PARD3)

CCW:	104686461(PARD3)

CBRC:

103620633(PARD3)

ETL:	114059488(PARD3)

ZAB:	102061025(PARD3)

ZLE:	135443611(PARD3)

ACHL:

103803509(PARD3)

SVG:	106855558(PARD3)

MMEA:

130582026(PARD3)

HRT:	120751183(PARD3)

FPG:	101922409(PARD3)

FCH:	102059808(PARD3)

CLV:	102084579(PARD3)

EGZ:	104133606(PARD3)

NNI:	104022281(PARD3)

PCRI:

104031257(PARD3)

EHS:	104514305(PARD3)

ACUN:

113477218(PARD3)

TALA:

104359877(PARD3)

PADL:

103918266(PARD3)

AFOR:

103898418(PARD3)

ACHC:

115339045(PARD3)

HALD:

104315754(PARD3)

HLE:	104842744(PARD3)

AGEN:

126037744

GCL:

127029977

MUI:	104540708(PARD3)

BREG:

104640065(PARD3)

GSTE:

104261789(PARD3)

LDI:	104344729(PARD3)

MNB:	103781691(PARD3)

OHA:	104339046(PARD3)

SHAB:

115610111(PARD3)

DPUB:

104297050(PARD3)

ACAR:

104521515(PARD3)

CPEA:

104397110(PARD3)

CVF:	104295368(PARD3)

RTD:	128905400(PARD3)

CUCA:

104066668(PARD3)

TEO:	104378866(PARD3)

AAM:	106489948(PARD3)

AROW:

112967400(PARD3)

NPD:	112955452(PARD3)

TGT:	104577151(PARD3)

DNE:	112984057(PARD3)

SCAM:

104150048(PARD3)

ASN:

102372201

AMJ:	102573113(PARD3)

CPOO:

109305786(PARD3)

GGN:	109291088(PARD3)

PSS:	102453652(PARD3)

CMY:	102936016(PARD3)

CCAY:

125631285(PARD3)

DCC:	119851780(PARD3)

CPIC:

101949299(PARD3)

TST:	117872071(PARD3)

CABI:

116823558(PARD3)

MRV:	120397806(PARD3)

ACS:	100561891(pard3)

ASAO:

132778954(PARD3)

PVT:	110082710(PARD3)

SUND:

121933097(PARD3)

PBI:	103063193(PARD3)

PMUR:

107284022(PARD3)

CTIG:

120310748

TSR:	106544000(PARD3)

PGUT:

117655294(PARD3)

APRI:

131197528(PARD3)

PTEX:

113442489(PARD3)

NSS:	113415016(PARD3)

VKO:	123020864(PARD3)

PMUA:

114607126(PARD3)

PRAF:

128398263(PARD3)

ZVI:	118091734(PARD3)

HCG:	128329835(PARD3)

GJA:	107123488(PARD3) 107123499

STOW:

125440786(PARD3)

EMC:	129337468(PARD3)

XLA:	108718759(pard3.L) 444443(pard3.S)

XTR:	733833(pard3)

NPR:	108783698(PARD3)

RTEM:

120940056(PARD3)

BBUF:

121002757(PARD3)

BGAR:

122939493(PARD3)

MUO:	115467241(PARD3)

GSH:	117354282(PARD3)

DRE:	101882925(pard3aa) 403050(pard3ab)

SRX:	107713921 107724536 107749111

SANH:

107653803(pard3) 107659281 107690576 107692754

SGH:	107552787 107557790 107563826 107593114(pard3)

CCAR:

109106569(pard3)

CAUA:

113040251 113042226 113066323 113120844

CGIB:

127934521 127946037 127950816 128013213

PTET:

122329427(pard3aa) 122360771(pard3ab)

LROH:

127155537(pard3aa) 127175811(pard3ab)

OMC:	131532895(pard3aa) 131551314(pard3ab)

PPRM:

120492272(pard3aa) 120495320(pard3ab)

RKG:	130072105(pard3aa) 130073369(pard3ab)

MAMB:

125250663(pard3ab) 125257746

CIDE:

127495415 127505829

MASI:

127431962 127434717 127441121 127443122

TROS:

130546771(pard3aa) 130554044(pard3ab)

TDW:	130413073(pard3aa) 130416000(pard3ab)

MANU:

129426443(pard3aa) 129442954(pard3ab)

IPU:	108271951(pard3aa)

IFU:	128614548(pard3aa)

PHYP:

113545491(pard3)

SMEO:

124383812(pard3aa)

TFD:	113644397(pard3aa)

TVC:	132845562(pard3aa)

TRN:	134302843(pard3ab) 134309827(pard3aa)

AMEX:

103031517(pard3ab) 103041224(pard3aa)

CMAO:

118796697(pard3ab) 118816236(pard3aa)

EEE:	113579404 113591642

CHAR:

105896310(pard3aa)

TRU:	101067082(pard3)

TFS:	130513723 130538624

TNG:	GSTEN00015223G001 GSTEN00016585G001

LCO:	104922457 104935178

NCC:	104966303(pard3)

TBEN:

117483768 117483951

CGOB:

115022096 115025632

PGEO:

117466036(pard3aa)

GACU:

117550227(pard3aa) 117560643

EMAC:

134866079 134884130

ELY:	117264743 117272342

EFO:	125881571 125901705

PLEP:

121951641 121960465

SLUC:

116044926(pard3ab) 116064851

ECRA:

117937671 117953799(pard3ab)

ESP:	116672026 116699792

PFLV:

114549067 114565626

GAT:

120811645

PPUG:

119198600 119204419

AFB:	129088942 129110418

CLUM:

117746238 117749660

PSWI:

130198373 130205917(pard3aa)

MSAM:

119882039 119901711(pard3ab) 119906686

SCHU:

122866596 122886361

CUD:	121520462 121527569

ALAT:

119008605 119010565(pard3ab)

MZE:	101463582 101476097

ONL:	100698856 100702913(pard3)

OAU:	116311274 116331649

OLA:	101157642(pard3) 101161760

OML:	112151185 112151407

CSAI:

133423716 133452483

XMA:	102227608 102236989

XCO:	114136816 114146071

XHE:	116711717 116721454(pard3)

PRET:

103479466(pard3) 103482325

PFOR:

103129117 103143381(pard3)

PLAI:

106955576 106959134(pard3)

PMEI:

106929164 106931385

GAF:	122824643 122841293(pard3ab)

PPRL:

129353103(pard3ab) 129364582

CVG:	107088350(pard3) 107101470

CTUL:

119787130 119787944

GMU:	124858061 124870592(pard3ab)

NFU:	107382653 107383437

KMR:	108243849 108245193

ALIM:

106521108(pard3) 106534000

NWH:

119415252

AOCE:

111563527(pard3) 111574045

MCEP:

124995993 125011240

CSEM:

103377042(pard3) 103396769

POV:	109629692(pard3) 109642726

SSEN:

122773356(pard3aa) 122781630

HHIP:

117754004 117778717

HSP:	118098540 118118305(pard3ab)

PPLT:

128425802 128454798

SMAU:

118291287 118310358

LCF:	108880948(pard3ab) 108898296

SDU:	111228205 111233861(pard3)

SLAL:

111659829 111668452

XGL:	120790065 120798511

HCQ:	109512654 109529494

SSCV:

125984621 125985892

SBIA:

133492457 133511217

PEE:	133396457 133411869

PTAO:

133470529 133489491

BPEC:

110161924 110165549(pard3)

MALB:

109965141 109967086

BSPL:

114844145

SJO:	128369481 128382231

SASA:

106568841 106578541 106599503

STRU:

115153707 115156868 115169829

OTW:	112215584 112226996(pard3ab) 112260417

OMY:	110508784 110530242 110535542

OGO:	123991147 124009995 124041922

ONE:	115103145 115104519 115114349

OKI:	109871558 109874536 109908714

OKE:	118361156 118394593(pard3ab) 118402172

SALP:

111956389 111979132

SNH:	120020398 120028005 120055864

CCLU:

121535161 121549961 121580868

ELS:	105017776 105019433

SFM:	108927720(pard3) 108937575

PKI:	111840222 111840756(pard3)

AANG:

118225438 118234049

LOC:	102686589(pard3)

PSPA:

121311053 121314090

ARUT:

117394603 117399699

PSEX:

120529617(pard3aa)

LCM:	102358408(PARD3)

CMK:

CPLA:

HOC:

LERI:

PMRN:

116944013 116948686(PARD3B)

LRJ:	133349680 133356128

BFO:

BBEL:

CIN:

SCLV:

SPU:	100893392 580534

LPIC:

129273975

APLC:

110973573

SKO:

100371218

DME:	Dmel_CG5055(baz)

DER:

6550139

DSE:

6618057

DSI:	Dsimw501_GD17331(Dsim_GD17331)

DYA:	Dyak_GE17646

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI16958

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ003808

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

MDL:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:	115881322 115891899

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

ATRA:

GMW:

PXY:

LGLY:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM257850

FOC:

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DMK:

DPZ:

PVM:

PJA:

PMOO:

HAME:

PCLA:

PTRU:

HAZT:

EAF:

LSM:

TCF:

PPOI:

119104129 119104149 119109747 119109750

DSV:

119442320

RSAN:

119387204

RMP:	119166782 119183687

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:	129230337 129232656

SDM:

118192474

PMEO:

129581878

CEL:	CELE_F54E7.3(par-3)

CBR:	CBG_08987(Cbr-par-3)

CRQ:	GCK72_010592

LOA:	LOAG_17791

TSP:

Tsp_00433

HRO:	HELRODRAFT_192383

PVUL:

PCAN:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MMER:

RPHI:

OBI:

OSN:

LAK:

SMM:	Smp_169430

OVI:	T265_00091

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

TAD:	TRIADDRAFT_55106

» show all

Reference

PMID:19812038

Authors

Khazaei MR, Puschel AW

Title

Phosphorylation of the par polarity complex protein Par3 at serine 962 is mediated by aurora a and regulates its function in neuronal polarity.

Journal

J Biol Chem 284:33571-9 (2009)
DOI:10.1074/jbc.M109.055897

Reference

PMID:12234671

Authors

Gao L, Macara IG, Joberty G

Title

Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding properties.

Journal

Gene 294:99-107 (2002)
DOI:10.1016/S0378-1119(02)00681-9

Sequence

[hsa:56288]

LinkDB

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