KEGG   ORTHOLOGY: K04283
Entry
K04283                      KO                                     
Symbol
TRYR
Name
trypanothione-disulfide reductase [EC:1.8.1.12]
Pathway
map00480  Glutathione metabolism
map01100  Metabolic pathways
Reaction
R03821  trypanathione:NADP+ oxidoreductase
R08356  bis(glutathionyl)spermine:NADP+ oxidoreductase
R08357  homotrypanothione:NADP+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    K04283  TRYR; trypanothione-disulfide reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.12  trypanothione-disulfide reductase
     K04283  TRYR; trypanothione-disulfide reductase
Other DBs
GO: 0015042
Genes
TBR: Tb10.406.0520
TBG: TbgDal_X12680
TCR: 503555.30
LMA: LMJF_05_0350(TRYR)
LIF: LINJ_05_0350(TRYR)
LDO: LDBPK_050350
LMI: LMXM_05_0350
LBZ: LBRM_05_0350(TRYR)
LPAN: LPMP_050340(TRYR)
AG: CAA78264(TPR) CAA80668
Reference
PMID:3718941
  Authors
Shames SL, Fairlamb AH, Cerami A, Walsh CT
  Title
Purification and characterization of trypanothione reductase from Crithidia fasciculata, a newly discovered member of the family of disulfide-containing flavoprotein reductases.
  Journal
Biochemistry 25:3519-26 (1986)
DOI:10.1021/bi00360a007
  Sequence
[ag:CAA78264]
Reference
PMID:7607216
  Authors
Cunningham ML, Fairlamb AH
  Title
Trypanothione reductase from Leishmania donovani. Purification, characterisation and inhibition by trivalent antimonials.
  Journal
Eur J Biochem 230:460-8 (1995)
DOI:10.1111/j.1432-1033.1995.0460h.x
  Sequence
[ag:CAA80668]
LinkDB

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