KEGG   ORTHOLOGY: K08294
Entry
K08294                      KO                                     
Symbol
MKK1_2
Name
mitogen-activated protein kinase kinase [EC:2.7.12.2]
Pathway
map04011  MAPK signaling pathway - yeast
map04139  Mitophagy - yeast
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04011 MAPK signaling pathway - yeast
    K08294  MKK1_2; mitogen-activated protein kinase kinase
 09140 Cellular Processes
  09141 Transport and catabolism
   04139 Mitophagy - yeast
    K08294  MKK1_2; mitogen-activated protein kinase kinase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K08294  MKK1_2; mitogen-activated protein kinase kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     K08294  MKK1_2; mitogen-activated protein kinase kinase
Protein kinases [BR:ko01001]
 Serine/threonine kinases: STE group
  STE7 family
   K08294  MKK1_2; mitogen-activated protein kinase kinase
Other DBs
COG: COG0515
GO: 0004708
Genes
SCE: YOR231W(MKK1) YPL140C(MKK2)
SEUB: DI49_5056 DI49_5324
SPAO: SPAR_O03520 SPAR_P01320
AGO: AGOS_ACR117W
ERC: Ecym_8337
KLA: KLLA0_D07304g
KMX: KLMA_20786(MKK1)
LTH: KLTH0D10670g
VPO: Kpol_1072p31
ZRO: ZYRO0F06798g
CGR: CAGL0J03828g
NCS: NCAS_0B01450(NCAS0B01450) NCAS_0C01580(NCAS0C01580)
NDI: NDAI_0E01310(NDAI0E01310)
TPF: TPHA_0G01730(TPHA0G01730)
TBL: TBLA_0B03990(TBLA0B03990)
TGB: HG536_0A07530
TDL: TDEL_0A05980(TDEL0A05980)
KAF: KAFR_0A03710(KAFR0A03710)
KNG: KNAG_0A03060(KNAG0A03060)
ZMK: HG535_0A05870
PPA: PAS_chr1-4_0271
DHA: DEHA2C15972g
PIC: PICST_35816
PGU: PGUG_00992
SPAA: SPAPADRAFT_71227
LEL: PVL30_000977(MKK1)
CAL: CAALFM_C205780CA(MKK2)
CTP: CTRG_01530
COT: CORT_0A08790
CDU: CD36_20220
CTEN: CANTEDRAFT_131976
YLI: YALI0B13178g
CLU: CLUG_01074
CLUS: A9F13_09g01265
CAUR: CJI96_0003217
SLB: AWJ20_2320(MKK2)
PKZ: C5L36_0C04930
BNN: FOA43_001620(MKK1)
BBRX: BRETT_004888
OPA: HPODL_01203
SLUD: SCDLUD_002133
NCR: NCU06419(mek-1)
NTE: NEUTE1DRAFT62379(NEUTE1DRAFT_62379)
SMP: SMAC_02183(putative_mek1)
PAN: PODANSg5429
PBEL: QC761_710270(MKK1)
PPSD: QC762_710270(MKK1)
PPSP: QC763_710270(MKK1)
PPSA: QC764_710270(MKK1)
TTT: THITE_2119959
MTM: MYCTH_81343
CTHR: CTHT_0070670
MGR: MGG_06482
PPEI: PpBr36_06075
PGRI: PgNI_00896
TMN: UCRPA7_2250
SSCK: SPSK_08933
FGR: FGSG_07295
FPU: FPSE_01082
FPOA: FPOAC1_011076
FVN: FVRRES_12096
FVR: FVEG_05280
FOX: FOXG_02117
NHE: NECHADRAFT_68573
FFC: NCS54_00583000
FKR: NCS57_00620700
FMU: J7337_002481
TRE: TRIREDRAFT_21168(mkk1)
TRR: M419DRAFT_23166
MAJ: MAA_05913
PCHM: VFPPC_02783
CMT: CCM_01460
AMUS: LMH87_004219
PLJ: VFPFJ_05591
PTKZ: JDV02_000889(MKK1)
VAL: VDBG_02628
VDA: VDAG_09823
CFJ: CFIO01_04337
CLUP: CLUP02_04136
CHIG: CH63R_03079
SAPO: SAPIO_CDS5766
ELA: UCREL1_11628
PFY: PFICI_05557
SSL: SS1G_00059
BFU: BCIN_03g07190(Bcmkk1)
MBE: MBM_03743
PSCO: LY89DRAFT_580278
GLZ: GLAREA_12918
ANI: ANIA_04189
AFM: AFUA_1G05800
ACT: ACLA_028730
NFI: NFIA_018920
AOR: AO090009000347
ANG: An18g03740
AFV: AFLA_011012
ALUC: AKAW2_31223A(MKK1)
ACHE: ACHE_11474A(MKK1)
APUU: APUU_60461S(MKK1)
PCS: N7525_000281
PDP: PDIP_69560
POU: POX_e06758
TMF: EYB26_000894
CIM: CIMG_03875
CPW: CPC735_004680
URE: UREG_02065
PBL: PAAG_01808
PBN: PADG_00495
ABE: ARB_05664
TVE: TRV_01194
AJE: HCAG_00181
BGH: BDBG_05031
PNO: SNOG_11919
PTE: PTT_12414
BZE: COCCADRAFT_95316
BSC: COCSADRAFT_29634
BOR: COCMIDRAFT_84874
AALT: CC77DRAFT_929814
ARAB: EKO05_0003534
ZTR: MYCGRDRAFT_71299(MgMkk1)
PFJ: MYCFIDRAFT_55590
FFU: CLAFUR5_02234
CBET: CB0940_00258
BCOM: BAUCODRAFT_175276
NPA: UCRNP2_300
TML: GSTUM_00005681001
SPO: SPBC543.07(pek1)
SOM: SOMG_03432(pek1)
CNE: CNE01930
CNB: CNBE1890
CNG: CNAG_02357
CGI: CGB_E2440W
CDEU: CNBG_4069
TMS: TREMEDRAFT_73380
TASA: A1Q1_07615
CCAC: CcaHIS019_0311410(MKK1)
PPL: POSPLDRAFT_113082
TVS: TRAVEDRAFT_41084 TRAVEDRAFT_56364
DSQ: DICSQDRAFT_50575
PCO: PHACADRAFT_258440
SHS: STEHIDRAFT_66877 STEHIDRAFT_69841
HIR: HETIRDRAFT_181084 HETIRDRAFT_320731
PSQ: PUNSTDRAFT_63321
ADL: AURDEDRAFT_54951
FME: FOMMEDRAFT_86379
GTR: GLOTRDRAFT_39064 GLOTRDRAFT_41026
RSX: RhiXN_06916 RhiXN_10626
CCI: CC1G_01579 CC1G_01983
ABP: AGABI1DRAFT38036(AGABI1DRAFT_38036)
ABV: AGABI2DRAFT70301(AGABI2DRAFT_70301)
MRR: Moror_6820
MORE: E1B28_000693
CPUT: CONPUDRAFT_52785
SLA: SERLADRAFT_414997
WSE: WALSEDRAFT_14707
WIC: J056_001989
UMA: UMAG_10855
PFP: PFL1_04472
SGRA: EX895_000309
MRT: MRET_4210
MSYM: MSY001_2211
PGR: PGTG_20747
PSTR: Pst134EA_019495
MLR: MELLADRAFT_38429
NGR: NAEGRDRAFT_58346
 » show all
Reference
PMID:8386320
  Authors
Irie K, Takase M, Lee KS, Levin DE, Araki H, Matsumoto K, Oshima Y
  Title
MKK1 and MKK2, which encode Saccharomyces cerevisiae mitogen-activated protein kinase-kinase homologs, function in the pathway mediated by protein kinase C.
  Journal
Mol Cell Biol 13:3076-83 (1993)
DOI:10.1128/MCB.13.5.3076
  Sequence
[sce:YOR231W YPL140C]
Reference
PMID:17711850
  Authors
Jimenez-Sanchez M, Cid VJ, Molina M
  Title
Retrophosphorylation of Mkk1 and Mkk2 MAPKKs by the Slt2 MAPK in the yeast cell integrity pathway.
  Journal
J Biol Chem 282:31174-85 (2007)
DOI:10.1074/jbc.M706270200
  Sequence
[sce:YOR231W YPL140C]
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