KEGG   ORTHOLOGY: K09447
Entry
K09447                      KO                                     
Symbol
IRF7
Name
interferon regulatory factor 7
Pathway
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04622  RIG-I-like receptor signaling pathway
map04623  Cytosolic DNA-sensing pathway
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05164  Influenza A
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05203  Viral carcinogenesis
map05417  Lipid and atherosclerosis
Disease
H00096  Defects of toll-like receptor signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K09447  IRF7; interferon regulatory factor 7
   04621 NOD-like receptor signaling pathway
    K09447  IRF7; interferon regulatory factor 7
   04622 RIG-I-like receptor signaling pathway
    K09447  IRF7; interferon regulatory factor 7
   04623 Cytosolic DNA-sensing pathway
    K09447  IRF7; interferon regulatory factor 7
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K09447  IRF7; interferon regulatory factor 7
  09172 Infectious disease: viral
   05161 Hepatitis B
    K09447  IRF7; interferon regulatory factor 7
   05160 Hepatitis C
    K09447  IRF7; interferon regulatory factor 7
   05164 Influenza A
    K09447  IRF7; interferon regulatory factor 7
   05162 Measles
    K09447  IRF7; interferon regulatory factor 7
   05168 Herpes simplex virus 1 infection
    K09447  IRF7; interferon regulatory factor 7
   05167 Kaposi sarcoma-associated herpesvirus infection
    K09447  IRF7; interferon regulatory factor 7
   05169 Epstein-Barr virus infection
    K09447  IRF7; interferon regulatory factor 7
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K09447  IRF7; interferon regulatory factor 7
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09447  IRF7; interferon regulatory factor 7
Transcription factors [BR:ko03000]
 Eukaryotic type
  Helix-turn-helix
   Tryptophan clusters interferon-regulating factors
    K09447  IRF7; interferon regulatory factor 7
Genes
HSA: 3665(IRF7)
PTR: 450927(IRF7)
GGO: 101138881(IRF7)
PON: 100460542(IRF7)
NLE: 100605304(IRF7)
HMH: 116466580(IRF7)
MCC: 699578(IRF7)
MCF: 102130894(IRF7)
MTHB: 126935835
MNI: 105494145(IRF7)
CSAB: 103226003(IRF7)
CATY: 105577208(IRF7)
PANU: 101005316(IRF7)
TGE: 112606379(IRF7)
MLEU: 105549339(IRF7)
RRO: 104682894(IRF7)
RBB: 108543524(IRF7)
TFN: 117079841(IRF7)
PTEH: 111520580(IRF7)
CANG: 105503197(IRF7)
CJC: 100405036(IRF7)
SBQ: 101034616(IRF7)
CIMI: 108288787(IRF7)
MMUR: 105874038(IRF7)
LCAT: 123642940(IRF7)
PCOQ: 105816570(IRF7)
OGA: 100950073(IRF7)
MMU: 54123(Irf7)
MCAL: 110297922(Irf7)
MPAH: 110333471(Irf7)
RNO: 293624(Irf7)
MCOC: 116103213(Irf7)
ANU: 117713181(Irf7)
MUN: 110553918(Irf7)
CGE: 100755889(Irf7)
MAUA: 101827190(Irf7)
PROB: 127228535(Irf7)
PLEU: 114693632(Irf7)
MORG: 121457785(Irf7)
MFOT: 126498320
AAMP: 119821228(Irf7)
NGI: 103751080(Irf7)
HGL: 101710824(Irf7)
CPOC: 101788200(Irf7)
CCAN: 109698071(Irf7)
DORD: 105998598(Irf7)
DSP: 122095034(Irf7)
PLOP: 125361218(Irf7)
NCAR: 124958721
MMMA: 107157099(Irf7)
OPI: 101519172(IRF7)
TUP: 102487659(IRF7)
GVR: 103609517(IRF7)
CFA: 119864198(IRF7)
CLUD: 112663568(IRF7)
VVP: 112914606(IRF7)
VLG: 121501592(IRF7)
NPO: 129494159(IRF7)
AML: 100474086(IRF7)
UMR: 103671092(IRF7)
UAH: 113248784(IRF7)
UAR: 123775465(IRF7)
ELK: 111150049
LLV: 125078240
MPUF: 101671751(IRF7)
MNP: 132016435(IRF7)
MLK: 131818289(IRF7)
NVS: 122913702(IRF7)
ORO: 101374020(IRF7)
EJU: 114201571(IRF7)
ZCA: 113914873(IRF7)
MLX: 118016222(IRF7)
NSU: 110582214(IRF7)
LWW: 102737602(IRF7)
FCA: 101084060(IRF7)
PYU: 121022797(IRF7)
PCOO: 112852158(IRF7)
PBG: 122484171(IRF7)
PVIV: 125176255(IRF7)
LRUF: 124527563
PPAD: 109259807(IRF7)
PUC: 125937759
AJU: 106988905
HHV: 120223400(IRF7)
BTA: 100125591(IRF7)
BOM: 102275978(IRF7)
BBIS: 104985722(IRF7)
CHX: 106503773(IRF7)
OAS: 101103683(IRF7)
BTAX: 128068703(IRF7)
ODA: 120874208(IRF7)
CCAD: 122430585(IRF7)
MBEZ: 129548601(IRF7)
SSC: 100037289(IRF7)
CFR: 116666573(IRF7)
CBAI: 105069905(IRF7)
CDK: 105105431(IRF7)
VPC: 102527909(IRF7)
BACU: 102999216(IRF7)
BMUS: 118898799(IRF7)
LVE: 103077222(IRF7)
OOR: 101277458(IRF7)
DLE: 111170280(IRF7)
PCAD: 102996452(IRF7)
PSIU: 116758553(IRF7)
NASI: 112402386(IRF7)
ECB: 100055087(IRF7)
EPZ: 103567336(IRF7)
EAI: 106824966(IRF7)
MMYO: 118648972(IRF7)
PKL: 118717964(IRF7)
EFUS: 103302547(IRF7)
MNA: 107542325(IRF7)
DRO: 112317444(IRF7)
SHON: 118982245(IRF7)
AJM: 119062180(IRF7)
PDIC: 114499187(IRF7)
PHAS: 123807315(IRF7)
MMF: 118643167(IRF7)
PPAM: 129073150(IRF7)
HAI: 109375630(IRF7)
RFQ: 117030454(IRF7)
PALE: 102897349(IRF7)
PGIG: 120584660(IRF7)
PVP: 105305954(IRF7)
RAY: 107507145(IRF7)
MJV: 108408637(IRF7)
TOD: 119248779(IRF7)
SARA: 101545292(IRF7)
SETR: 126018828(IRF7)
LAV: 100655418(IRF7)
TMU: 101352078
ETF: 101647709(IRF7)
DNM: 101422123(IRF7)
AFZ: 127541173
PCW: 110202995(IRF7)
OAA: 103167211(IRF7)
GGA: 396330(IRF7)
PCOC: 116239026(IRF7)
MGP: 100545324(IRF7)
CJO: 107314507(IRF7)
TPAI: 128087034(IRF7)
LMUT: 125694397(IRF7)
NMEL: 110402123(IRF7)
APLA: 101795904(IRF7)
ACYG: 106031780(IRF7)
CATA: 118250835(IRF7)
AFUL: 116490112(IRF7)
TGU: 100222919(IRF7)
LSR: 110484492(IRF7)
SCAN: 103824089(IRF7)
PMOA: 120511392(IRF7)
OTC: 121344835(IRF7)
PRUF: 121361028(IRF7)
GFR: 102042226(IRF7)
FAB: 101807197(IRF7)
OMA: 130253702(IRF7)
PHI: 102105004(IRF7)
PMAJ: 107205854(IRF7)
CCAE: 111930730(IRF7)
CCW: 104690931(IRF7)
CBRC: 103620899(IRF7)
ETL: 114068489(IRF7)
ZAB: 102069248(IRF7)
ZLE: 135448539(IRF7)
ACHL: 103807651(IRF7)
SVG: 106851530(IRF7)
MMEA: 130576644(IRF7)
HRT: 120754782(IRF7)
FPG: 101922355(IRF7)
FCH: 102060208(IRF7)
CLV: 102095157(IRF7)
EGZ: 104127102(IRF7)
NNI: 104017322(IRF7)
ACUN: 113480983(IRF7)
TALA: 116964290(IRF7)
PADL: 103916457(IRF7)
AFOR: 103896227(IRF7)
ACHC: 115352198(IRF7)
HLE: 104828705(IRF7)
AGEN: 126047183
GCL: 127017145
CSTI: 104556829(IRF7)
MUI: 104542263(IRF7)
SHAB: 115607732(IRF7)
CPEA: 104387657(IRF7)
CVF: 104290298(IRF7)
RTD: 128908086(IRF7)
CUCA: 104068984(IRF7)
AAM: 106494854(IRF7)
AROW: 112962692(IRF7)
NPD: 112943579(IRF7)
TGT: 104569020(IRF7)
DNE: 112987949(IRF7)
ASN: 102387082(IRF7)
AMJ: 102564189(IRF7)
CPOO: 109318206(IRF7)
GGN: 109299222(IRF7)
PSS: 102462917(IRF7)
CMY: 102929901(IRF7)
CCAY: 125638692(IRF7)
DCC: 119857432(IRF7)
CPIC: 101952035(IRF7)
TST: 117877356(IRF7)
CABI: 116820756(IRF7)
MRV: 120404379(IRF7)
ACS: 103278516(irf7)
ASAO: 132771432(IRF7)
PVT: 110074187(IRF7)
SUND: 121920016(IRF7)
PBI: 103050794(IRF7)
PMUR: 107292762
TSR: 106546498(IRF7)
PGUT: 117665185(IRF7)
APRI: 131184969(IRF7)
PTEX: 113440313(IRF7)
NSS: 113412511(IRF7)
VKO: 123021261(IRF7)
PMUA: 114599743(IRF7)
PRAF: 128416945(IRF7)
ZVI: 118088557(IRF7)
GJA: 107116862
STOW: 125427552(IRF7)
EMC: 129324796(IRF7)
XLA: 108713897(irf7.L)
XTR: 100496395(irf7)
NPR: 108786686
RTEM: 120917370(IRF7)
BBUF: 120980984(IRF7)
BGAR: 122920037(IRF7)
MUO: 115469032(IRF7)
GSH: 117352066(IRF7)
DRE: 393650(irf7)
SRX: 107707540 107709955
SANH: 107675276 107675380
SGH: 107562829 107573044
CCAR: 109070803(irf7) 109074487
CAUA: 113043606(irf7) 113067120
CGIB: 127946816 128013744
PTET: 122330493(irf7)
LROH: 127156255(irf7)
OMC: 131534161(irf7)
PPRM: 120473335(irf7)
RKG: 130086007(irf7)
MAMB: 125247591(irf7)
CIDE: 127507424
MASI: 127435828 127437578
TROS: 130552090(irf7)
TDW: 130414172(irf7)
MANU: 129433924 129433925
IPU: 108275163
IFU: 128618134(irf7)
PHYP: 113529482(irf7)
SMEO: 124392314(irf7)
TFD: 113659981(irf7)
TVC: 132857510(irf7)
TRN: 134309402(irf7)
AMEX: 103045043(irf7)
CMAO: 118811522(irf7)
EEE: 113581332(irf7)
CHAR: 105908787(irf7)
TRU: 101069060(irf7)
TFS: 130536734(irf7)
TNG: GSTEN00021491G001
LCO: 104920456(irf7)
NCC: 104945359
TBEN: 117491839(irf7)
CGOB: 115009699(irf7)
PGEO: 117448551(irf7)
GACU: 117545909(irf7)
EMAC: 134878443(irf7)
ELY: 117261911(irf7)
EFO: 125887595(irf7)
PLEP: 121949730(irf7)
SLUC: 116038367(irf7)
ECRA: 117949266(irf7)
ESP: 116694062(irf7)
PFLV: 114559933(irf7)
GAT: 120809125(irf7)
PPUG: 119195758(irf7)
AFB: 129107827(irf7)
CLUM: 117732758(irf7)
PSWI: 130195132(irf7)
MSAM: 119894137(irf7)
SCHU: 122874789(irf7)
CUD: 121514452(irf7)
ALAT: 119024096(irf7)
MZE: 101476656(irf7)
ONL: 100706192(irf7)
OAU: 116333299(irf7)
OML: 112152165(irf7)
CSAI: 133444698(irf7)
XMA: 102220023(irf7)
XCO: 114135642(irf7)
XHE: 116711873(irf7)
PRET: 103466137(irf7)
PFOR: 103151620(irf7)
PLAI: 106937983(irf7)
PMEI: 106905741(irf7)
GAF: 122834945(irf7)
PPRL: 129361019(irf7)
CVG: 107085418(irf7)
CTUL: 119776808(irf7)
GMU: 124878312(irf7)
NFU: 107388997(irf7)
KMR: 108239926(irf7)
ALIM: 106515646(irf7)
NWH: 119416007(irf7)
AOCE: 111584372(irf7)
MCEP: 125014633(irf7)
CSEM: 103380393(irf7)
POV: 109624406(irf7)
SSEN: 122775708(irf7)
HHIP: 117762676(irf7)
HSP: 118109310(irf7)
PPLT: 128443937(irf7)
SMAU: 118315060(irf7)
LCF: 108875433
SDU: 111228393(irf7)
SLAL: 111661782(irf7)
XGL: 120792961(irf7)
HCQ: 109530495
SSCV: 125970413
SBIA: 133501925(irf7)
PEE: 133403092(irf7)
PTAO: 133477782(irf7)
BPEC: 110169308
MALB: 109970775
BSPL: 114857241(irf7)
SJO: 128359224(irf7)
SASA: 100192336(irf7) 100329194(irf7b)
STRU: 115152118 115197304
OTW: 112218673 112252506
OMY: 100750228 110497044
OGO: 124002100 124003375(irf7)
ONE: 115109512 115134162(irf7)
OKI: 109867501 109889483
OKE: 118370930 118395745(irf7)
SALP: 111952126 111962579
SNH: 120053484 120066374(irf7)
CCLU: 121532193 121577211
ELS: 105018339(irf7)
SFM: 108942108
PKI: 111859397(irf7)
AANG: 118215723(irf7)
LOC: 102698664(irf7)
PSPA: 121294755(irf7) 121330180
ARUT: 117432304 117435108
PSEX: 120523300(irf7)
LCM: 102367315(IRF7)
CMK: 103189086(irf7)
RTP: 109935038
HOC: 132824457(irf7)
SDM: 118191705
 » show all
Reference
PMID:11073981
  Authors
Marie I, Smith E, Prakash A, Levy DE
  Title
Phosphorylation-induced dimerization of interferon regulatory factor 7 unmasks DNA binding and a bipartite transactivation domain.
  Journal
Mol Cell Biol 20:8803-14 (2000)
DOI:10.1128/MCB.20.23.8803-8814.2000
Reference
PMID:9315633
  Authors
Zhang L, Pagano JS
  Title
IRF-7, a new interferon regulatory factor associated with Epstein-Barr virus latency.
  Journal
Mol Cell Biol 17:5748-57 (1997)
DOI:10.1128/MCB.17.10.5748
  Sequence
[hsa:3665]
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