KEGG   ORTHOLOGY: K09831
Entry
K09831                      KO                                     
Symbol
ERG5, CYP61A
Name
sterol 22-desaturase [EC:1.14.19.41]
Pathway
map00100  Steroid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00102  Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
Reaction
R07506  ergosta-5,7,24(28)-trien-3beta-ol,NADPH:oxygen oxidoreductase (22,23-dehydrogenating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    K09831  ERG5, CYP61A; sterol 22-desaturase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K09831  ERG5, CYP61A; sterol 22-desaturase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.41  sterol 22-desaturase
     K09831  ERG5, CYP61A; sterol 22-desaturase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, fungi type
  CYP61 family
   K09831  ERG5, CYP61A; sterol 22-desaturase
Other DBs
COG: COG2124
GO: 0000249
Genes
SCE: YMR015C(ERG5)
SEUB: DI49_4102
SPAO: SPAR_M01390
AGO: AGOS_ABR053C
KLA: KLLA0_D11242g
KMX: KLMA_60417(cyp524A1)
LTH: KLTH0D07832g
VPO: Kpol_1056p10
ZRO: ZYRO0E06204g
CGR: CAGL0M07656g
NCS: NCAS_0A12700(NCAS0A12700)
NDI: NDAI_0B01560(NDAI0B01560)
TPF: TPHA_0I02420(TPHA0I02420)
TBL: TBLA_0H02650(TBLA0H02650)
TGB: HG536_0G01250
TDL: TDEL_0B06510(TDEL0B06510)
KAF: KAFR_0A02110(KAFR0A02110)
KNG: KNAG_0M02100(KNAG0M02100)
ZMK: HG535_0G03560
PPA: PAS_chr3_0507
DHA: DEHA2D06182g
PIC: PICST_73043(ERG5)
PGU: PGUG_05085
SPAA: SPAPADRAFT_63544(ERG5)
LEL: PVL30_005321(ERG5)
CAL: CAALFM_C702840CA(ERG5)
CTP: CTRG_04983
COT: CORT_0G04140
CDU: CD36_72510
CTEN: CANTEDRAFT_115386
YLI: YALI0A18062g
CLU: CLUG_04246
CLUS: A9F13_04g02805
CAUR: CJI96_0004850 CJI96_0004910
SLB: AWJ20_75(ERG5)
PKZ: C5L36_0B12520
BNN: FOA43_004793(ERG5)
BBRX: BRETT_002777(ERG5)
OPA: HPODL_01958
SLUD: SCDLUD_004216
NCR: NCU05278
NTE: NEUTE1DRAFT116692(NEUTE1DRAFT_116692)
SMP: SMAC_01710
PAN: PODANSg6262 PODANSg7995
PBEL: QC761_202070 QC761_304420(ERG5)
PPSD: QC762_202070 QC762_304420(ERG5)
PPSP: QC763_202070 QC763_304420(ERG5)
PPSA: QC764_202070 QC764_304420(ERG5)
TTT: THITE_128412
MTM: MYCTH_73679
CTHR: CTHT_0029760
MGR: MGG_06047
PPEI: PpBr36_02869
PGRI: PgNI_01835
TMN: UCRPA7_7946
SSCK: SPSK_00476
FGR: FGSG_01959 FGSG_03686
FPU: FPSE_01847 FPSE_09181
FPOA: FPOAC1_002075 FPOAC1_006089
FVN: FVRRES_02319 FVRRES_06686
FVR: FVEG_07284 FVEG_08786
FOX: FOXG_04166 FOXG_09685
NHE: NECHADRAFT_72313 NECHADRAFT_72652
FFC: NCS54_01269600 NCS54_01305200
FKR: NCS57_01239900 NCS57_01291900
FMU: J7337_010705 J7337_012541
TRE: TRIREDRAFT_122166 TRIREDRAFT_58689
TRR: M419DRAFT_141218 M419DRAFT_74177
MAW: MAC_08636
MAJ: MAA_01109
PCHM: VFPPC_03546
CMT: CCM_02962
AMUS: LMH87_000586 LMH87_006973
PLJ: VFPFJ_00660 VFPFJ_08344
PTKZ: JDV02_004750 JDV02_007982(ERG5)
VAL: VDBG_00192 VDBG_00755
VDA: VDAG_00367 VDAG_08476
CFJ: CFIO01_05732 CFIO01_13734
CLUP: CLUP02_04776 CLUP02_14903
CHIG: CH63R_04552 CH63R_14243
SAPO: SAPIO_CDS4161 SAPIO_CDS7005
ELA: UCREL1_11694
PFY: PFICI_04403 PFICI_13034
SSL: SS1G_09832
BFU: BCIN_07g01120(Bcerg5)
MBE: MBM_06688
PSCO: LY89DRAFT_257563 LY89DRAFT_584410
GLZ: GLAREA_02023 GLAREA_06590
ANI: ANIA_04042
AFM: AFUA_1G03950
ACT: ACLA_008020 ACLA_030640
NFI: NFIA_020740
AOR: AO090003000253 AO090003000954
ANG: An01g02810 An11g03230
AFV: AFLA_000720 AFLA_001436
ALUC: AKAW2_20450S(ERG5_1) AKAW2_80298S(ERG5_2)
ACHE: ACHE_11570S(ERG5)
APUU: APUU_40308A(ERG5) APUU_60358A
PCS: N7525_005484 N7525_010907
PDP: PDIP_21270
POU: POX_e06874
TMF: EYB26_008188
TRG: TRUGW13939_00550 TRUGW13939_08662
CIM: CIMG_05009
CPW: CPC735_068810
URE: UREG_06546
PBL: PAAG_11073(PAAG_00230)
PBN: PADG_07898
ABE: ARB_03814
TVE: TRV_05093
AJE: HCAG_06013
BGH: BDBG_03201
PNO: SNOG_06055
PTE: PTT_19871
BZE: COCCADRAFT_88203
BSC: COCSADRAFT_221542
BOR: COCMIDRAFT_93916
AALT: CC77DRAFT_991604
ARAB: EKO05_0000970
ZTR: MYCGRDRAFT_55438(CYP-70)
PFJ: MYCFIDRAFT_49450
FFU: CLAFUR5_02386
CBET: CB0940_03149
BCOM: BAUCODRAFT_489380
NPA: UCRNP2_2755
TML: GSTUM_00005882001
SPO: SPAC19A8.04(erg5)
SOM: SOMG_03716(erg5)
CNE: CNF03720
CNB: CNBF1100
CNG: CNAG_06644
CGI: CGB_F1500C
CDEU: CNBG_1921
TMS: TREMEDRAFT_40696
TASA: A1Q1_00690
CCAC: CcaHIS019_0405230(ERG5)
TVS: TRAVEDRAFT_140384
DSQ: DICSQDRAFT_66936
PCO: PHACADRAFT_246788
SHS: STEHIDRAFT_123767
HIR: HETIRDRAFT_141009(cpm111)
PSQ: PUNSTDRAFT_59236
ADL: AURDEDRAFT_109660
FME: FOMMEDRAFT_106824 FOMMEDRAFT_155371
GTR: GLOTRDRAFT_53715
RSX: RhiXN_01858
LBC: LACBIDRAFT_187166(ERG5)
CCI: CC1G_01671
ABP: AGABI1DRAFT66440(AGABI1DRAFT_66440)
ABV: AGABI2DRAFT189837(AGABI2DRAFT_189837)
PCUB: JR316_0000711
MRR: Moror_12729
MORE: E1B28_009893
SCM: SCHCO_02609502(SCHCODRAFT_02609502)
CPUT: CONPUDRAFT_94730
SLA: SERLADRAFT_459032
WSE: WALSEDRAFT_69870
WIC: J056_001310
UMA: UMAG_00350
PFP: PFL1_03644
SGRA: EX895_000577
MGL: MGL_0310
MRT: MRET_0994
MSYM: MSY001_2710
 » show all
Reference
PMID:8635732
  Authors
Skaggs BA, Alexander JF, Pierson CA, Schweitzer KS, Chun KT, Koegel C, Barbuch R, Bard M
  Title
Cloning and characterization of the Saccharomyces cerevisiae C-22 sterol desaturase gene, encoding a second cytochrome P-450 involved in ergosterol biosynthesis.
  Journal
Gene 169:105-9 (1996)
DOI:10.1016/0378-1119(95)00770-9
  Sequence
[sce:YMR015C]
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