KEGG ORTHOLOGY: K10163

ORTHOLOGY: K10163

Entry

K10163                      KO

Symbol

FOXP3, IPEX

Name

forkhead box P3

Pathway

map04659

Th17 cell differentiation

map05321

Inflammatory bowel disease

Disease

H00107

Other well-defined immunodeficiency syndromes

H00512

Permanent neonatal diabetes mellitus

H01971

IPEX syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K10163  FOXP3, IPEX; forkhead box P3
09160 Human Diseases
  09163 Immune disease
   05321 Inflammatory bowel disease
    K10163  FOXP3, IPEX; forkhead box P3
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K10163  FOXP3, IPEX; forkhead box P3
Transcription factors [BR:ko03000]
Eukaryotic type
  Helix-turn-helix
   Fork head/winged helix other regulators
    K10163  FOXP3, IPEX; forkhead box P3

Genes

HSA:	50943(FOXP3)

PTR:	740909(FOXP3)

PPS:	100990082(FOXP3)

GGO:	101130276(FOXP3)

PON:	100432872(FOXP3)

NLE:	100606735(FOXP3)

HMH:	116811688(FOXP3)

MCC:	574303(FOXP3)

MCF:	102120882(FOXP3)

MTHB:

126945552

MNI:	105493930(FOXP3)

CSAB:

103231966(FOXP3)

CATY:

105573104(FOXP3)

PANU:

101018460(FOXP3)

TGE:	112616491(FOXP3)

MLEU:

105547692(FOXP3)

RRO:	104661817(FOXP3)

RBB:	108521365(FOXP3)

TFN:	117083982(FOXP3)

PTEH:

111535206(FOXP3)

CANG:

105514985(FOXP3)

CJC:	100408633(FOXP3)

SBQ:	101035423(FOXP3)

CIMI:

108293047(FOXP3)

CSYR:

103277254(FOXP3)

MMUR:

105856420(FOXP3)

LCAT:

123628133(FOXP3)

PCOQ:

105816846(FOXP3)

OGA:	100963348(FOXP3)

MMU:	20371(Foxp3)

MCAL:

110286217(Foxp3)

MPAH:

110313390(Foxp3)

RNO:	317382(Foxp3)

MCOC:

116102278(Foxp3)

ANU:	117694619(Foxp3)

MUN:	110561916(Foxp3)

CGE:	100757421(Foxp3)

MAUA:

101829655(Foxp3)

PROB:

127218368(Foxp3)

PLEU:

114701283(Foxp3)

MORG:

121444336(Foxp3)

MFOT:

126512862

AAMP:

119805251(Foxp3)

NGI:	103741675(Foxp3)

HGL:	101722447(Foxp3)

CPOC:

100735602(Foxp3)

CCAN:

109697194(Foxp3)

DORD:

105997836(Foxp3)

DSP:	122098784(Foxp3)

PLOP:

125343307(Foxp3)

NCAR:

124971755

MMMA:

107159848(Foxp3)

OCU:

100348270

OPI:	101520267(FOXP3)

TUP:	102482059(FOXP3)

GVR:	103602698(FOXP3)

CFA:	491876(FOXP3)

CLUD:

112673113(FOXP3)

VVP:	112907239(FOXP3)

VLG:	121483416(FOXP3)

NPO:	129518897(FOXP3)

AML:	100467988(FOXP3)

UMR:	103667451(FOXP3)

UAH:	113265955(FOXP3)

UAR:	123797190(FOXP3)

ELK:

111150492

LLV:

125091733

MPUF:

101690558(FOXP3)

MNP:	132007141(FOXP3)

MLK:	131821230(FOXP3)

NVS:	122897069(FOXP3)

ORO:	101365686(FOXP3)

EJU:	114216722(FOXP3)

ZCA:	113931543(FOXP3)

MLX:	118010407(FOXP3)

NSU:	110570728(FOXP3)

LWW:	102735586(FOXP3)

FCA:	100037405(FOXP3)

PYU:	121026063(FOXP3)

PCOO:

112870983(FOXP3)

PBG:	122477614(FOXP3)

PVIV:

125157246(FOXP3)

LRUF:

124509539

PTG:	102972991(FOXP3)

PPAD:

109248099(FOXP3)

PUC:

125931682

AJU:

106989015

HHV:	120221005(FOXP3)

BTA:	506053(FOXP3)

BOM:	102285670(FOXP3)

BIU:	109555264(FOXP3)

BBUB:

102405704(FOXP3)

BBIS:

104983691(FOXP3)

CHX:	102188755(FOXP3)

OAS:	100240742(FOXP3)

BTAX:

128070305(FOXP3)

ODA:	120882131(FOXP3)

CCAD:

122434758(FOXP3)

MBEZ:

129534895(FOXP3)

SSC:	444998(FOXP3)

CFR:	102505184(FOXP3)

CBAI:

105079416(FOXP3)

CDK:	105106315(FOXP3)

VPC:	102541841(FOXP3)

BACU:

102998254(FOXP3)

BMUS:

118888644(FOXP3)

LVE:	103083465(FOXP3)

OOR:	101280345(FOXP3)

DLE:	111169472(FOXP3)

PCAD:

102993238(FOXP3)

PSIU:

116747498(FOXP3)

NASI:

112399844(FOXP3)

ECB:	100052226(FOXP3)

EPZ:	103545451(FOXP3)

EAI:	106826960(FOXP3)

MYB:	102259977(FOXP3)

MYD:	102770845(FOXP3)

MMYO:

118654732(FOXP3)

MLF:	102434633(FOXP3)

PKL:	118731819(FOXP3)

EFUS:

103301307(FOXP3)

MNA:	107541386(FOXP3)

DRO:	112322442(FOXP3)

SHON:

118998348(FOXP3)

AJM:	119059501(FOXP3)

PDIC:

114505049(FOXP3)

PHAS:

123832835(FOXP3)

MMF:	118635901(FOXP3)

PPAM:

129065200(FOXP3)

HAI:	109374800(FOXP3)

RFQ:	117028933(FOXP3)

PALE:

102882840(FOXP3)

PGIG:

120587069(FOXP3)

PVP:	105309050(FOXP3)

RAY:	107515002(FOXP3)

MJV:	108404218(FOXP3)

TOD:	119246157(FOXP3)

SARA:

101549177(FOXP3)

SETR:

125999334(FOXP3)

LAV:	100667999(FOXP3)

TMU:

101361863

ETF:	101660817(FOXP3)

DNM:	101446573(FOXP3)

MDO:	100019598(FOXP3)

GAS:	123254380(FOXP3)

SHR:	100928075(FOXP3)

AFZ:

127542399

PCW:	110201010(FOXP3)

OAA:	100075823(FOXP3)

LSR:	110482650(FOXP3)

OTC:

121340074

HRT:	120748222(FOXP3)

ACHC:

115338228

AGEN:

126035188

SHAB:

115603524(FOXP3)

ASN:	102376811(FOXP3)

CMY:	114022693(FOXP3)

CCAY:

125628311

DCC:	119847471(FOXP3)

CABI:

116838402

MRV:	120388184(FOXP3)

ACS:	103277757(foxp3)

ASAO:

132765473(FOXP3)

PVT:	110078611(FOXP3)

SUND:

121922705(FOXP3)

PBI:

103050763

CTIG:

120311307

PGUT:

117675531(FOXP3)

PTEX:

113443443

NSS:

113417679

VKO:

123029961

PMUA:

114587352(FOXP3)

PRAF:

128404923(FOXP3)

ZVI:	118097597(FOXP3)

STOW:

125430334

XLA:	100158268(foxp3.L) 108700514(foxp3.S)

XTR:	100485747(foxp3)

NPR:	108788500(FOXP3)

RTEM:

120913035(FOXP3)

BBUF:

120977794(FOXP3)

BGAR:

122919316(FOXP3)

MUO:

115463484

GSH:	117368180(FOXP3)

DRE:	101886699(foxp3b)

SRX:	107711972 107731149 107731227 107745815

SANH:

107668086 107669635 107679368 107680010

SGH:	107549951 107550167 107550508 107591799

CCAR:

109050537 109068212 109082345 109095299

CAUA:

113076458 113080146 113093984 113107273 113107588 113107645

CGIB:

127962987 128018687

PTET:

122350201(foxp3b)

LROH:

127169259(foxp3b)

OMC:	131545187(foxp3b)

PPRM:

120469066(foxp3b)

RKG:	130094652(foxp3b)

MAMB:

125279769(foxp3b)

CIDE:

127518085

MASI:

127415439 127424200

TROS:

130568161(foxp3b)

TDW:	130440293(foxp3b)

MANU:

129414606(foxp3b)

IPU:	108264896(foxp3b)

IFU:	128607868(foxp3b)

PHYP:

113535941

SMEO:

124399423(foxp3b)

TFD:	113655942(foxp3b)

TVC:	132854127(foxp3b)

TRN:	134317992(foxp3b)

AMEX:

103040869(foxp3)

CMAO:

118812874(foxp3b)

EEE:

113579121

CHAR:

105898901(foxp3b)

TRU:

101070400

TFS:	130529447(foxp3b)

LCO:

104932792

NCC:

104956470

TBEN:

117481501(foxp3b)

CGOB:

115016671

PGEO:

117449843(foxp3b)

GACU:

117535478(foxp3b)

EMAC:

134871683(foxp3b)

ELY:	117258034(foxp3b)

EFO:	125892013(foxp3b)

PLEP:

121947415(foxp3b)

SLUC:

116050885(foxp3b)

ECRA:

117948031(foxp3b)

ESP:

PFLV:

GAT:

PPUG:

AFB:	129099961(foxp3b)

CLUM:

117733554(foxp3b)

MSAM:

119904976

SCHU:

122882468(foxp3b)

CUD:	121517864(foxp3b)

ALAT:

119022827(foxp3b)

MZE:	101474386(foxp3)

ONL:	100707959(foxp3b)

OAU:	116323397(foxp3b)

OLA:

101163234

OML:	112140034(foxp3b)

CSAI:

133440998(foxp3b)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122836989 122840371

PPRL:

CVG:

CTUL:

GMU:

KMR:

ALIM:

NWH:

AOCE:

MCEP:

125003507(foxp3b)

CSEM:

103384892

POV:

109630697

SSEN:

122776590(foxp3b)

HHIP:

117765143(foxp3b)

HSP:	118111056(foxp3b)

PPLT:

128442275(foxp3b)

SMAU:

118317399(foxp3b)

LCF:	108900475(foxp3b)

SDU:

111219161

SLAL:

111670617

XGL:	120804014(foxp3b)

MALB:

109965199

BSPL:

114859437(foxp3b)

SJO:	128356967(foxp3b)

SASA:

100526661(foxp3)

STRU:

115166299 115168251

OTW:	112222058(foxp3b)

OMY:	100653438(foxp3-2) 100653439(foxp3-1)

OGO:	124021671 124045069

ONE:	115102225 115132023

OKI:	109869867 109907879

OKE:	118359744 118361265

SALP:

111976461

SNH:	120058955 120060722(foxp3b)

CCLU:

121537461 121546559(foxp3b)

ELS:

105013833

SFM:	108934796(foxp3)

PKI:	111847802(foxp3)

PSPA:

121328315

ARUT:

117404293

LCM:	102353004(FOXP3)

HOC:

132809453

» show all

Reference

PMID:11138001

Authors

Brunkow ME, Jeffery EW, Hjerrild KA, Paeper B, Clark LB, Yasayko SA, Wilkinson JE, Galas D, Ziegler SF, Ramsdell F

Title

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.

Journal

Nat Genet 27:68-73 (2001)
DOI:10.1038/83784

Sequence

[hsa:50943]

Reference

PMID:24523508

Authors

Mu J, Tai X, Iyer SS, Weissman JD, Singer A, Singer DS

Title

Regulation of MHC class I expression by Foxp3 and its effect on regulatory T cell function.

Journal

J Immunol 192:2892-903 (2014)
DOI:10.4049/jimmunol.1302847

Sequence

[mmu:20371]

LinkDB

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