KEGG   ORTHOLOGY: K11029
Entry
K11029                      KO                                     
Symbol
cyaA
Name
anthrax edema toxin adenylate cyclase [EC:4.6.1.1]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
Module
M00859  Bacillus anthracis pathogenicity signature, anthrax toxin
Reaction
R00089  ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming)
R00434  GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K11029  cyaA; anthrax edema toxin adenylate cyclase
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins
    K11029  cyaA; anthrax edema toxin adenylate cyclase
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K11029  cyaA; anthrax edema toxin adenylate cyclase
Bacterial toxins [BR:ko02042]
 Type III toxins: Intracellular toxins
  Adenylate cyclase
   Anthrax edema toxin
    K11029  cyaA; anthrax edema toxin adenylate cyclase
Other DBs
GO: 0008294
Genes
BAR: GBAA_pXO1_0142(cya)
BAH: BAMEG_A0137(cya)
BAI: BAA_A0144(cya)
BAX: H9401_5614
BANT: A16_60275
BANR: A16R_61295
BANS: BAPAT_pXO10137(cyaA)
BANH: HYU01_28670
BANV: DJ46_5684(cya)
BCX: BCA_A0128(cya)
BAL: BACI_pCIXO101300(cya)
BTF: YBT020_27824
BWW: bwei_5707(cya)
BRW: GOP56_07410
 » show all
Reference
PMID:17313374
  Authors
Turk BE
  Title
Manipulation of host signalling pathways by anthrax toxins.
  Journal
Biochem J 402:405-17 (2007)
DOI:10.1042/BJ20061891
LinkDB

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