KEGG ORTHOLOGY: K11067

ORTHOLOGY: K11067

Entry

K11067                      KO

Symbol

NAGS

Name

N-acetylglutamate synthase [EC:2.3.1.1]

Pathway

map00220

Arginine biosynthesis

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map01210

2-Oxocarboxylic acid metabolism

map01230

Biosynthesis of amino acids

Reaction

R00259

acetyl-CoA:L-glutamate N-acetyltransferase

Disease

H01032

N-acetylglutamate synthase deficiency

H01398

Primary hyperammonemia (Urea cycle disorders)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09105 Amino acid metabolism
   00220 Arginine biosynthesis
    K11067  NAGS; N-acetylglutamate synthase
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.1  amino-acid N-acetyltransferase
     K11067  NAGS; N-acetylglutamate synthase

Other DBs

GO:

0004042

Genes

HSA:	162417(NAGS)

PTR:	468274(NAGS)

PPS:	100993190(NAGS)

GGO:	101144816(NAGS)

PON:	100458979(NAGS)

NLE:	100586170(NAGS)

HMH:	116474925(NAGS)

MCC:	714102(NAGS)

MCF:	102137808(NAGS)

MTHB:

126938679

MNI:	105469347(NAGS)

CSAB:

103243341(NAGS)

CATY:

105584956(NAGS)

PANU:

101002565(NAGS)

TGE:	112609724(NAGS)

MLEU:

105543789(NAGS)

RRO:	104654701(NAGS)

RBB:	108532173(NAGS)

TFN:	117066899(NAGS)

PTEH:

111525804(NAGS)

CANG:

105510355(NAGS)

CJC:	100399057(NAGS)

SBQ:	101049265(NAGS)

CIMI:

108294313(NAGS)

MMUR:

105883536(NAGS)

LCAT:

123621014(NAGS)

PCOQ:

105822135(NAGS)

OGA:	100942802(NAGS)

MMU:	217214(Nags)

MCAL:

110305773(Nags)

MPAH:

110332410(Nags)

RNO:	303563(Nags)

MCOC:

116077403(Nags)

ANU:	117711497(Nags)

MUN:	110551874(Nags)

CGE:	100752620(Nags)

MAUA:

101837415(Nags)

PROB:

127217434(Nags)

PLEU:

114702216(Nags)

MORG:

121436268(Nags)

MFOT:

126510121

AAMP:

119812951(Nags)

NGI:	103738424(Nags)

HGL:	101696446(Nags)

CPOC:

100729618(Nags)

CCAN:

109697062(Nags)

DORD:

105997507(Nags)

DSP:	122103327(Nags)

PLOP:

125366376(Nags)

NCAR:

124981384

MMMA:

107150527(Nags)

OCU:

100357937

OPI:	101522260(NAGS)

TUP:	102482669(NAGS)

GVR:	103591842(NAGS)

CFA:	490943(NAGS)

CLUD:

112655200(NAGS)

VVP:	112910674(NAGS)

VLG:	121473791(NAGS)

NPO:	129516535(NAGS)

AML:	100467996(NAGS)

UMR:	103665859(NAGS)

UAH:	113265368(NAGS)

UAR:	123803226(NAGS)

ELK:

111158100

LLV:

125087762

MPUF:

101688059(NAGS)

MNP:	132003277(NAGS)

MLK:	131816340(NAGS)

NVS:	122906152(NAGS)

ORO:	101375297(NAGS)

EJU:	114200551(NAGS)

ZCA:	113939464(NAGS)

MLX:	118024962(NAGS)

NSU:	110573297(NAGS)

LWW:	102745468(NAGS)

FCA:	101097029(NAGS)

PYU:	121045080(NAGS)

PBG:	122485665(NAGS)

PVIV:

125158698(NAGS)

LRUF:

124522251

PPAD:

109258214(NAGS)

PUC:

125926615

AJU:

113596281

HHV:	120222897(NAGS)

BTA:	538004(NAGS)

BOM:	102271021(NAGS)

BIU:	109574152(NAGS)

BBUB:

102414047(NAGS)

BBIS:

104982997(NAGS)

CHX:	102185952(NAGS)

OAS:	101112658(NAGS)

BTAX:

128065286(NAGS)

ODA:	120867046(NAGS)

CCAD:

122440732(NAGS)

MBEZ:

129544473(NAGS)

SSC:	100048960(NAGS)

CFR:	102515366(NAGS)

CBAI:

105072561(NAGS)

CDK:	105101048(NAGS)

VPC:	102539643(NAGS)

BACU:

103006583(NAGS)

BMUS:

118887205(NAGS)

LVE:	103069463(NAGS)

OOR:	101281958(NAGS)

DLE:	111170197(NAGS)

PCAD:

102977441(NAGS)

PSIU:

116746285(NAGS)

NASI:

112410481(NAGS)

ECB:	100051467(NAGS)

EPZ:	103551222(NAGS)

EAI:	106836501(NAGS)

MYB:	102263594(NAGS)

MYD:	102751953(NAGS)

MMYO:

118671427(NAGS)

MLF:	102426917(NAGS)

PKL:	118726335(NAGS)

EFUS:

103293045(NAGS)

MNA:	107528900(NAGS)

DRO:	112298870(NAGS)

SHON:

119002237(NAGS)

AJM:	119041790(NAGS)

PDIC:

114503953(NAGS)

PHAS:

123817559(NAGS)

MMF:	118635041(NAGS)

PPAM:

129086441(NAGS)

HAI:	109394985(NAGS)

RFQ:	117013646(NAGS)

PALE:

102886734(NAGS)

PGIG:

120589203(NAGS)

PVP:	105303501(NAGS)

RAY:	107508127(NAGS)

MJV:	108410019(NAGS)

TOD:	119231326(NAGS)

SARA:

101541835(NAGS)

SETR:

126017574(NAGS)

LAV:	100676437(NAGS)

TMU:

101353043

ETF:	101639107(NAGS)

DNM:	101424703(NAGS)

MDO:	100022816(NAGS)

GAS:	123247932(NAGS)

SHR:	100929411(NAGS)

AFZ:

127560330

PCW:	110215720(NAGS)

OAA:	100083700(NAGS)

ASN:	102386490(NAGS)

AMJ:	109280240(NAGS)

PSS:	102446110(NAGS)

CMY:	102933799(NAGS)

CCAY:

125626818(NAGS)

DCC:	119849159(NAGS)

CPIC:

101951616(NAGS)

TST:	117869238(NAGS)

CABI:

116831484(NAGS)

MRV:	120392252(NAGS)

XLA:	108700842(nags.L) 108702180

XTR:	100488724(nags)

NPR:	108801867(NAGS)

RTEM:

120918237(NAGS)

BBUF:

121003489(NAGS)

BGAR:

122941771(NAGS)

MUO:	115482179(NAGS)

GSH:	117347677(NAGS)

DRE:	557716(nags)

SRX:

107740635

SANH:

107662425

SGH:

107585096

CCAR:

109062590(nags) 109105522

CAUA:

113046699(nags)

CGIB:

127953713

PTET:

122333758(nags)

LROH:

127160912(nags)

OMC:	131537056(nags)

PPRM:

120489173(nags)

RKG:	130070323(nags)

MAMB:

125272799(nags)

CIDE:

127509794

MASI:

127452229

IPU:

108261093

IFU:	128600505(nags)

PHYP:

113528510(nags)

SMEO:

124397392(nags)

TFD:	113638126(nags)

TVC:	132861428(nags)

AMEX:

103022484(nags)

CMAO:

118821550(nags)

EEE:	113569793(nags)

CHAR:

105912864(nags)

TRU:	101068816(nags)

TFS:	130514697(nags)

TNG:	GSTEN00021079G001

LCO:	104936976(nags)

TBEN:

117499362(nags)

CGOB:

115012631(nags)

PGEO:

117443358(nags)

EMAC:

134877514(nags)

ELY:	117269062(nags)

EFO:	125879292(nags)

PLEP:

121956881(nags)

SLUC:

116045094(nags)

ECRA:

117958605(nags)

ESP:	116703521(nags)

PFLV:

114570308(nags)

GAT:	120828329(nags)

PPUG:

119221011(nags)

AFB:	129098901(nags)

CLUM:

117735229(nags)

PSWI:

130189052(nags)

MSAM:

119882334(nags)

SCHU:

122868416(nags)

CUD:	121529090(nags)

ALAT:

119014338(nags)

MZE:	101475627(nags)

ONL:	100697065(nags)

OAU:	116319536(nags)

OLA:	101175301(nags)

OML:	112141528(nags)

CSAI:

133421521(nags)

XMA:	102220302(nags)

XCO:	114148561(nags)

XHE:	116736266(nags)

PRET:

103468287(nags)

PFOR:

103149229(nags)

PLAI:

106952109(nags)

PMEI:

106909723(nags)

GAF:	122821339(nags)

PPRL:

129363894(nags)

CVG:	107103847(nags)

CTUL:

119777868(nags)

GMU:

124863735

NFU:	107382230(nags)

KMR:	108228334(nags)

ALIM:

106525248(nags)

NWH:	119422052(nags)

AOCE:

111581744(nags)

MCEP:

124998322(nagS)

CSEM:

103393622(nags)

POV:	109641415(nags)

SSEN:

122785842(nags)

HHIP:

117765960(nags)

HSP:	118123685(nags)

PPLT:

128458554(nags)

SMAU:

118289027(nags)

LCF:	108898586 108902146

SDU:	111223697(nags)

SLAL:

111662410(nags)

XGL:	120785648(nags)

HCQ:	109524774(nags)

BPEC:

110172122(nags)

BSPL:

114860633(nags)

SJO:	128378716(nags)

SASA:

106607476(nags)

STRU:

115196809(nags)

OTW:	112225913(nags)

OMY:	110486155(nags)

OGO:	124016513(nags)

ONE:	115104045(nags)

OKI:	109898320(nags)

OKE:	118365184(nags)

SALP:

111981461(nags)

SNH:	120034444(nags)

CCLU:

121550493 121569685

ELS:	105005741(nags)

SFM:	108941574(nags)

AANG:

118216718(nags)

LOC:	102691759(nags)

PSPA:

121301827(nags)

ARUT:

117433525(nags)

PSEX:

120517930(nags)

LCM:	102352471(NAGS)

CMK:	103183775(nags)

RTP:	109928300(nags)

CPLA:

122539914(nags)

HOC:	132830926(nags)

LERI:

129710324(nags)

BFO:

BBEL:

SPU:

LPIC:

APLC:

LGI:	LOTGIDRAFT_238302

PCAN:

BGT:

GAE:

HRF:

HRJ:

OBI:

OSN:

LAK:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:	114517641 114517682

XEN:

124452501

» show all

Reference

PMID:12049647

Authors

Caldovic L, Morizono H, Yu X, Thompson M, Shi D, Gallegos R, Allewell NM, Malamy MH, Tuchman M

Title

Identification, cloning and expression of the mouse N-acetylglutamate synthase gene.

Journal

Biochem J 364:825-31 (2002)
DOI:10.1042/BJ20020161

Sequence

[mmu:217214]

Reference

PMID:12459178

Authors

Caldovic L, Morizono H, Gracia Panglao M, Gallegos R, Yu X, Shi D, Malamy MH, Allewell NM, Tuchman M

Title

Cloning and expression of the human N-acetylglutamate synthase gene.

Journal

Biochem Biophys Res Commun 299:581-6 (2002)
DOI:10.1016/S0006-291X(02)02696-7

Sequence

[hsa:162417]

LinkDB

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