Entry
Symbol
URA2
Name
carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:
6.3.5.5 2.1.3.2 ]
Pathway
map00250 Alanine, aspartate and glutamate metabolism
Module
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Reaction
R00256 L-glutamine amidohydrolase
R00575 HCO3-:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)
R01395 ATP:carbamate phosphotransferase
R01397 carbamoyl-phosphate:L-aspartate carbamoyltransferase
R10948 ATP:HCO3- phosphotransferase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
K11541 URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
K11541 URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
Enzymes [BR:ko01000 ]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.2 aspartate carbamoyltransferase
K11541 URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
K11541 URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
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Reference
Authors
Souciet JL, Nagy M, Le Gouar M, Lacroute F, Potier S
Title
Organization of the yeast URA2 gene: identification of a defective dihydroorotase-like domain in the multifunctional carbamoylphosphate synthetase-aspartate transcarbamylase complex.
Journal
Sequence
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