Entry
Symbol
hisIE
Name
phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:
3.5.4.19 3.6.1.31 ]
Pathway
map01110 Biosynthesis of secondary metabolites
Module
M00026 Histidine biosynthesis, PRPP => histidine
Reaction
R04035 phosphoribosyl-ATP pyrophosphohydrolase
R04037 1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
K11755 hisIE; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase
Enzymes [BR:ko01000 ]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.19 phosphoribosyl-AMP cyclohydrolase
K11755 hisIE; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.31 phosphoribosyl-ATP diphosphatase
K11755 hisIE; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase
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Reference
Authors
Fujimori K, Ohta D
Title
Isolation and characterization of a histidine biosynthetic gene in Arabidopsis encoding a polypeptide with two separate domains for phosphoribosyl-ATP pyrophosphohydrolase and phosphoribosyl-AMP cyclohydrolase.
Journal
Sequence
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