KEGG ORTHOLOGY: K12239

ORTHOLOGY: K12239

Entry

K12239                      KO

Symbol

pchE

Name

L-cysteine---[L-cysteinyl-carrier protein] ligase PchE [EC:6.2.1.69]

Pathway

map01053

Biosynthesis of siderophore group nonribosomal peptides

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01053 Biosynthesis of siderophore group nonribosomal peptides
    K12239  pchE; L-cysteine---[L-cysteinyl-carrier protein] ligase PchE
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K12239  pchE; L-cysteine---[L-cysteinyl-carrier protein] ligase PchE
Enzymes [BR:ko01000]
6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.69  L-cysteine---[L-cysteinyl-carrier protein] ligase
     K12239  pchE; L-cysteine---[L-cysteinyl-carrier protein] ligase PchE
Polyketide biosynthesis proteins [BR:ko01008]
Nonribosomal peptide synthetase (NRPS)
  Nonlinear NRPS
   Pyochelin synthetase
    K12239  pchE; L-cysteine---[L-cysteinyl-carrier protein] ligase PchE

Other DBs

COG:

COG1020

Genes

PGE:	LG71_26195

PAE:	PA4226(pchE)

PAEV:

N297_4358

PAEI:

N296_4358

PAU:	PA14_09270(pchE)

PAP:	PSPA7_0874(pchE)

PAG:	PLES_07011(pchE)

PAF:	PAM18_0711(pchE)

PNC:	NCGM2_5471(pchE)

PAEB:

NCGM1900_0733(pchE)

PDK:	PADK2_03540

PSG:	G655_03575

PRP:	M062_22265

PAEP:

PAER:

PAEM:

PAEL:

PAES:

PAEU:

BN889_04700(pchE_1) BN889_04701(pchE_2)

PAEG:

AI22_00220

PAEC:

M802_4356

PAEO:

M801_4224

PFL:	PFL_3493(pchE)

PPRC:

PFLCHA0_c35340(irp2)

PPRO:

PPC_3647(pchE)

PVR:	PverR02_15520

PCZ:	PCL1606_27860

PSEM:

TO66_16990

PSOS:

POS17_3636(pchE)

PSEP:

C4K39_5486

SAJS:

QO259_16205

MAER:

DAI18_17600

BPS:	BPSS0586(pchE)

BPM:	BURPS1710b_A2150(pchE)

BPL:	BURPS1106A_A0787

BPD:	BURPS668_A0877

BPSE:

BPSM:

BPSU:

BPSD:

BPZ:	BP1026B_II0646(pchE)

BPQ:	BPC006_II0832

BPK:

BPSH:

BPSA:

BPSO:

BUT:

BTE:	BTH_II1828(pchE)

BTQ:

BTJ:

BTZ:

BTV:

BTHE:

BTHM:

BTHA:

BTHL:

BUR:	Bcep18194_B0672

BCM:	Bcenmc03_5289

BCH:	Bcen2424_4998

BCJ:	BCAM2230(pchE)

BCEO:

I35_6121(pchE)

BCED:

BCEP:

BSEM:

BSTL:

BARI:

BGP:	BGL_1c20580(pchE)

BPLA:

bpln_1g19100

SECH:

B18_04275

ALI:	AZOLI_p20160(pchE)

RPAY:

THYR:

PFT:

AEQ:

NIE:	KV110_22880

SCYE:

R2B67_00090

SCB:

SCAB_1481

SRC:	M271_09930

SVE:

SVEN_0512

SGU:	SGLAU_04470(nrps1C) SGLAU_04650(nrps1E)

SPHW:

NFX46_19185

SPAD:

DVK44_09640

SDUR:

M4V62_41900

ASE:	ACPL_6158(nrps2C)

ACTS:

ACWT_6026

AOU:	ACTOB_004298

» show all

Reference

PMID:10555976

Authors

Quadri LE, Keating TA, Patel HM, Walsh CT

Title

Assembly of the Pseudomonas aeruginosa nonribosomal peptide siderophore pyochelin: In vitro reconstitution of aryl-4, 2-bisthiazoline synthetase activity from PchD, PchE, and PchF.

Journal

Biochemistry 38:14941-54 (1999)
DOI:10.1021/bi991787c

Sequence

[pau:PA14_09270]

LinkDB

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