KEGG   ORTHOLOGY: K12363
Entry
K12363                      KO                                     
Symbol
RASGRP4
Name
RAS guanyl-releasing protein 4
Pathway
map04010  MAPK signaling pathway
map04014  Ras signaling pathway
map05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K12363  RASGRP4; RAS guanyl-releasing protein 4
   04014 Ras signaling pathway
    K12363  RASGRP4; RAS guanyl-releasing protein 4
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K12363  RASGRP4; RAS guanyl-releasing protein 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K12363  RASGRP4; RAS guanyl-releasing protein 4
Domain-containing proteins not elsewhere classified [BR:ko04990]
 EF-hand domain-containing proteins
  Other EF-hand domain-containing proteins
   K12363  RASGRP4; RAS guanyl-releasing protein 4
Other DBs
GO: 0005088
Genes
HSA: 115727(RASGRP4)
PTR: 468867(RASGRP4)
PPS: 100983271(RASGRP4)
GGO: 101140025(RASGRP4)
PON: 100444206(RASGRP4)
NLE: 100590994(RASGRP4)
HMH: 116480739(RASGRP4)
MCC: 719595(RASGRP4)
MCF: 102120963(RASGRP4)
MTHB: 126942141
MNI: 105495404(RASGRP4)
CSAB: 103234634(RASGRP4)
CATY: 105594542(RASGRP4)
PANU: 101023506(RASGRP4)
TGE: 112613560(RASGRP4)
MLEU: 105534626(RASGRP4)
RRO: 104679960(RASGRP4)
RBB: 108525393 108538988(RASGRP4)
TFN: 117092476(RASGRP4)
PTEH: 111554039(RASGRP4)
CANG: 105519212(RASGRP4)
CJC: 103789934(RASGRP4)
SBQ: 101048039(RASGRP4)
CIMI: 108287890(RASGRP4)
CSYR: 103276875(RASGRP4)
MMUR: 105876828(RASGRP4)
LCAT: 123624374(RASGRP4)
PCOQ: 105820520(RASGRP4)
OGA: 100961453(RASGRP4)
MMU: 233046(Rasgrp4)
MCAL: 110298815(Rasgrp4)
MPAH: 110329512(Rasgrp4)
RNO: 170668(Rasgrp4)
MCOC: 116101938(Rasgrp4)
ANU: 117720118(Rasgrp4)
MUN: 110552560(Rasgrp4)
CGE: 100765723(Rasgrp4)
MAUA: 101840429(Rasgrp4)
PROB: 127238435(Rasgrp4)
PLEU: 114684979(Rasgrp4)
MORG: 121449592(Rasgrp4)
MFOT: 126486727
AAMP: 119821876(Rasgrp4)
NGI: 103750713(Rasgrp4)
HGL: 101708596(Rasgrp4)
CPOC: 100727572(Rasgrp4)
CCAN: 109695823(Rasgrp4)
DORD: 105993178(Rasgrp4)
DSP: 122097593(Rasgrp4)
PLOP: 125338677(Rasgrp4)
NCAR: 124967269
MMMA: 107151494(Rasgrp4)
OCU: 100350559
OPI: 101521344(RASGRP4)
TUP: 102492372(RASGRP4)
GVR: 103591480(RASGRP4)
CFA: 484528(RASGRP4)
CLUD: 112645519(RASGRP4)
VVP: 112928417(RASGRP4)
VLG: 121485211(RASGRP4)
NPO: 129500647(RASGRP4)
AML: 100471293(RASGRP4)
UMR: 103661068(RASGRP4)
UAH: 113243614(RASGRP4)
UAR: 123784572(RASGRP4)
ELK: 111161497
LLV: 125089719
MPUF: 101688552(RASGRP4)
MNP: 132005631(RASGRP4)
MLK: 131817764(RASGRP4)
NVS: 122911635(RASGRP4)
ORO: 101365772(RASGRP4)
EJU: 114198914(RASGRP4)
ZCA: 113935777(RASGRP4)
MLX: 118022697(RASGRP4)
NSU: 110590079(RASGRP4)
LWW: 102728846(RASGRP4)
FCA: 101094467(RASGRP4)
PYU: 121011504(RASGRP4)
PBG: 122494101(RASGRP4)
PVIV: 125153092(RASGRP4)
LRUF: 124511162
PTG: 102971379(RASGRP4)
PPAD: 109256631(RASGRP4)
PUC: 125915269
AJU: 106980248
HHV: 120220621(RASGRP4)
BTA: 529375(RASGRP4)
BOM: 102266520(RASGRP4)
BIU: 109571998(RASGRP4)
BBUB: 102412421(RASGRP4)
BBIS: 104995313(RASGRP4)
CHX: 102178937(RASGRP4)
OAS: 101112342(RASGRP4)
BTAX: 128063466(RASGRP4)
ODA: 120872482(RASGRP4)
CCAD: 122421130(RASGRP4)
MBEZ: 129546863(RASGRP4)
SSC: 100516199(RASGRP4)
CFR: 102510291(RASGRP4)
CBAI: 105075578(RASGRP4)
CDK: 105096949(RASGRP4)
VPC: 102534549(RASGRP4)
BACU: 103019665(RASGRP4)
BMUS: 118885726(RASGRP4)
LVE: 103069074(RASGRP4)
OOR: 101277798(RASGRP4)
DLE: 111180895(RASGRP4)
PCAD: 102996298(RASGRP4)
PSIU: 116743443(RASGRP4)
NASI: 112392206(RASGRP4)
ECB: 100064247(RASGRP4)
EPZ: 103541053(RASGRP4)
EAI: 106836100(RASGRP4)
MYB: 102251967(RASGRP4)
MYD: 102763301(RASGRP4)
MMYO: 118674089(RASGRP4)
MLF: 102439442(RASGRP4)
PKL: 118702398(RASGRP4)
EFUS: 103284349(RASGRP4)
MNA: 107532208(RASGRP4)
DRO: 112320197(RASGRP4)
SHON: 118976320(RASGRP4)
AJM: 119046726(RASGRP4)
PDIC: 114511084(RASGRP4)
PHAS: 123823849(RASGRP4)
MMF: 118639314(RASGRP4)
PPAM: 129083119(RASGRP4)
HAI: 109395316(RASGRP4)
RFQ: 117034648(RASGRP4)
PALE: 102885173(RASGRP4)
PGIG: 120596314(RASGRP4)
PVP: 105300188(RASGRP4)
RAY: 107520966(RASGRP4)
MJV: 108388253(RASGRP4)
TOD: 119250160(RASGRP4)
SARA: 101550382(RASGRP4)
SETR: 126028506(RASGRP4)
LAV: 100654736(RASGRP4)
TMU: 101351284
ETF: 101646752(RASGRP4)
DNM: 101428055(RASGRP4)
MDO: 100013191(RASGRP4)
GAS: 123243002(RASGRP4)
SHR: 100916458(RASGRP4)
AFZ: 127556161
PCW: 110202423(RASGRP4)
OAA: 100083583(RASGRP4)
ASN: 102380115(RASGRP4)
CMY: 114021289(RASGRP4)
CCAY: 125628361(RASGRP4)
DCC: 119847262(RASGRP4)
CPIC: 101941532(RASGRP4)
TST: 117889121(RASGRP4)
CABI: 116838912(RASGRP4)
MRV: 120388723(RASGRP4)
ACS: 100558232(rasgrp4)
ASAO: 132780183(RASGRP4)
PVT: 110075736(RASGRP4)
SUND: 121915138(RASGRP4)
PBI: 103057214(RASGRP4)
PMUR: 107293913(RASGRP4)
CTIG: 120319872(RASGRP4)
PGUT: 117677713(RASGRP4)
APRI: 131204709(RASGRP4)
PTEX: 113446037(RASGRP4)
VKO: 123025952(RASGRP4)
PMUA: 114603220(RASGRP4)
PRAF: 128418256(RASGRP4)
ZVI: 118086488(RASGRP4)
HCG: 128333087(RASGRP4)
GJA: 107117013
 » show all
Reference
PMID:11880369
  Authors
Reuther GW, Lambert QT, Rebhun JF, Caligiuri MA, Quilliam LA, Der CJ
  Title
RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia.
  Journal
J Biol Chem 277:30508-14 (2002)
DOI:10.1074/jbc.M111330200
  Sequence
[hsa:115727]
Reference
PMID:21779502
  Authors
Stone JC
  Title
Regulation and Function of the RasGRP Family of Ras Activators in Blood Cells.
  Journal
Genes Cancer 2:320-34 (2011)
DOI:10.1177/1947601911408082
LinkDB

DBGET integrated database retrieval system