KEGG   ORTHOLOGY: K12697
Entry
K12697            Tight     KO                                     
Symbol
D4H
Name
deacetoxyvindoline 4-hydroxylase [EC:1.14.11.20]
Pathway
map00901  Indole alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00965  Vindoline biosynthesis, tabersonine => vindoline
Reaction
R05857  desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4b-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00901 Indole alkaloid biosynthesis
    K12697  D4H; deacetoxyvindoline 4-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.20  deacetoxyvindoline 4-hydroxylase
     K12697  D4H; deacetoxyvindoline 4-hydroxylase
Other DBs
GO: 0050590
Genes
AG: AAB97311(D4H)
Reference
PMID:9290645
  Authors
Vazquez-Flota F, De Carolis E, Alarco AM, De Luca V
  Title
Molecular cloning and characterization of desacetoxyvindoline-4-hydroxylase, a 2-oxoglutarate dependent-dioxygenase involved in the biosynthesis of vindoline in Catharanthus roseus (L.) G. Don.
  Journal
Plant Mol Biol 34:935-48 (1997)
DOI:10.1023/A:1005894001516
  Sequence
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