KEGG   ORTHOLOGY: K12744
Entry
K12744                      KO                                     
Symbol
cefE
Name
deacetoxycephalosporin-C synthase [EC:1.14.20.1]
Pathway
map00311  Penicillin and cephalosporin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00673  Cephamycin C biosynthesis, aminoadipate + cycteine + valine => cephamycin C
Reaction
R05301  penicillin-N,2-oxoglutarate:oxygen oxidoreductase (ring-expanding)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00311 Penicillin and cephalosporin biosynthesis
    K12744  cefE; deacetoxycephalosporin-C synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K12744  cefE; deacetoxycephalosporin-C synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.20  With 2-oxoglutarate as one donor, and the other dehydrogenated
    1.14.20.1  deacetoxycephalosporin-C synthase
     K12744  cefE; deacetoxycephalosporin-C synthase
Polyketide biosynthesis proteins [BR:ko01008]
 Nonribosomal peptide tailoring proteins
  Others
   K12744  cefE; deacetoxycephalosporin-C synthase
Other DBs
GO: 0050599
Genes
SCLF: BB341_07740
SCT: SCAT_5687(cefE)
SCY: SCATT_56870
AAB: A4R43_03205
AMYY: YIM_39200(cefE2)
Reference
PMID:2644235
  Authors
Kovacevic S, Weigel BJ, Tobin MB, Ingolia TD, Miller JR
  Title
Cloning, characterization, and expression in Escherichia coli of the Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase.
  Journal
J Bacteriol 171:754-60 (1989)
DOI:10.1128/JB.171.2.754-760.1989
  Sequence
LinkDB

DBGET integrated database retrieval system