KEGG   ORTHOLOGY: K12921
Entry
K12921            Tight     KO                                     
Symbol
TDC1
Name
taxadiene synthase [EC:4.2.3.17]
Pathway
map00904  Diterpenoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R06305  geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxadiene forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00904 Diterpenoid biosynthesis
    K12921  TDC1; taxadiene synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.3  Acting on phosphates
    4.2.3.17  taxadiene synthase
     K12921  TDC1; taxadiene synthase
Other DBs
GO: 0050553
Genes
AG: AAC49310(TDC1)
Reference
PMID:8621577
  Authors
Wildung MR, Croteau R
  Title
A cDNA clone for taxadiene synthase, the diterpene cyclase that catalyzes the committed step of taxol biosynthesis.
  Journal
J Biol Chem 271:9201-4 (1996)
DOI:10.1074/jbc.271.16.9201
  Sequence
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