KEGG   ORTHOLOGY: K13226
Entry
K13226                      KO                                     
Symbol
BX5, CYP71C3, CYP71C8
Name
2-hydroxy-1,4-benzoxazin-3-one monooxygenase [EC:1.14.14.110]
Pathway
map00402  Benzoxazinoid biosynthesis
map00999  Biosynthesis of various plant secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00952  Benzoxazinoid biosynthesis, indoleglycerol phosphate => DIMBOA-glucoside
Reaction
R07423  2-hydroxy-2H-1,4-benzoxazin-3(4H)-one,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00402 Benzoxazinoid biosynthesis
    K13226  BX5, CYP71C3, CYP71C8; 2-hydroxy-1,4-benzoxazin-3-one monooxygenase
   00999 Biosynthesis of various plant secondary metabolites
    K13226  BX5, CYP71C3, CYP71C8; 2-hydroxy-1,4-benzoxazin-3-one monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K13226  BX5, CYP71C3, CYP71C8; 2-hydroxy-1,4-benzoxazin-3-one monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.110  2-hydroxy-1,4-benzoxazin-3-one monooxygenase
     K13226  BX5, CYP71C3, CYP71C8; 2-hydroxy-1,4-benzoxazin-3-one monooxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP71 family
   K13226  BX5, CYP71C3, CYP71C8; 2-hydroxy-1,4-benzoxazin-3-one monooxygenase
Genes
ATS: 109753210
TAES: 123101968 123110085 123110235 123110236 123119084
TUA: 125506869
ZMA: 103652726
AG: BAB87819(CYP71C8v2) CAA72207(BX5)
Reference
PMID:9235894 (CYP71C3)
  Authors
Frey M, Chomet P, Glawischnig E, Stettner C, Grun S, Winklmair A, Eisenreich W, Bacher A, Meeley RB, Briggs SP, Simcox K, Gierl A.
  Title
Analysis of a chemical plant defense mechanism in grasses.
  Journal
Science 277:696-9 (1997)
DOI:10.1126/science.277.5326.696
  Sequence
Reference
PMID:7823905
  Authors
Frey M, Kliem R, Saedler H, Gierl A
  Title
Expression of a cytochrome P450 gene family in maize.
  Journal
Mol Gen Genet 246:100-9 (1995)
DOI:10.1007/BF00290138
Reference
  Authors
Nomura T, Ishihara A, Yanagita RC, Endo TR, Iwamura H.
  Title
Three genomes differentially contribute to the biosynthesis of benzoxazinones in hexaploid wheat.
  Journal
Proc Natl Acad Sci U S A 102:16490-5 (2005)
DOI:10.1073/pnas.0505156102
Reference
PMID:11976964 (CYP71C8)
  Authors
Nomura T, Ishihara A, Imaishi H, Endo TR, Ohkawa H, Iwamura H
  Title
Molecular characterization and chromosomal localization of cytochrome P450 genes involved in the biosynthesis of cyclic hydroxamic acids in hexaploid wheat.
  Journal
Mol Genet Genomics 267:210-7 (2002)
DOI:10.1007/s00438-002-0653-x
  Sequence
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