KEGG   ORTHOLOGY: K13257
Entry
K13257                      KO                                     
Symbol
CYP93C
Name
2-hydroxyisoflavanone synthase [EC:1.14.14.87]
Pathway
map00943  Isoflavonoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00941  Isoflavone biosynthesis, liquiritigenin/naringenin => daidzein/genistein
Reaction
R07715  6,7,4'-trihydroxyflavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating, aryl migration)
R07777  liquiritigenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating, aryl migration)
R07778  naringenin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating, aryl migration)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00943 Isoflavonoid biosynthesis
    K13257  CYP93C; 2-hydroxyisoflavanone synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K13257  CYP93C; 2-hydroxyisoflavanone synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.87  2-hydroxyisoflavanone synthase
     K13257  CYP93C; 2-hydroxyisoflavanone synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP93 family
   K13257  CYP93C; 2-hydroxyisoflavanone synthase
Other DBs
GO: 0033770
Genes
GMX: 100037450(IFS1) 606705(IFS2)
GSJ: 114374378 114374486 114419594
PVU: PHAVU_003G051700g PHAVU_003G0518001 PHAVU_003G074000g
VRA: 106763981 106780381
VAR: 108332082 108333348
VUN: 114175870 114177618 114177620 114177979
VUM: 124839830 124842155
CCAJ: 109791295 109794853
APRC: 113857513 113859872
MTR: 25493067 25493068 25493071
TPRA: 123918472
CAM: 101495474(cyp93C3) 101495803
LJA: Lj4g3v0485090.1(Lj4g3v0485090.1) Lj4g3v0485100.1(Lj4g3v0485100.1) Lj4g3v0485970.1(Lj4g3v0485970.1) Lj4g3v0485980.1(Lj4g3v0485980.1) Lj4g3v0486150.1(Lj4g3v0486150.1)
AIP: 107631190
AG: BAA76380(CYP93C2)
 » show all
Reference
PMID:10375412 (CYP93C1)
  Authors
Steele CL, Gijzen M, Qutob D, Dixon RA
  Title
Molecular characterization of the enzyme catalyzing the aryl migration reaction of isoflavonoid biosynthesis in soybean.
  Journal
Arch Biochem Biophys 367:146-50 (1999)
DOI:10.1006/abbi.1999.1238
  Sequence
[gmx:606705]
Reference
PMID:10557230 (CYP93C2)
  Authors
Akashi T, Aoki T, Ayabe Si
  Title
Cloning and functional expression of a cytochrome P450 cDNA encoding 2-hydroxyisoflavanone synthase involved in biosynthesis of the isoflavonoid skeleton in licorice.
  Journal
Plant Physiol 121:821-8 (1999)
DOI:10.1104/pp.121.3.821
  Sequence
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