KEGG   ORTHOLOGY: K13311
Entry
K13311                      KO                                     
Symbol
desVI, eryCVI
Name
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase [EC:2.1.1.234]
Pathway
map00523  Polyketide sugar unit biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01250  Biosynthesis of nucleotide sugars
Module
M00797  dTDP-D-desosamine biosynthesis
Reaction
R06427  S-adenosyl-L-methionine:dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose 3-N,N-dimethyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K13311  desVI, eryCVI; dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.234  dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
     K13311  desVI, eryCVI; dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
Genes
SGRF: SGFS_016240
SCYE: R2B67_24635
SCAD: DN051_13790
STIR: DDW44_27830 DDW44_27885
SKA: CP970_39725 CP970_39870
SRK: FGW37_13085
SFIC: EIZ62_04025
SGAL: CP966_29020
SCIN: CP977_27965 CP977_28100
STSU: B7R87_21945 B7R87_21970
SEN: SACE_0718(eryCVI)
ACTI: UA75_17810
ACAD: UA74_17275
AHG: AHOG_15450(desVI)
MCAB: HXZ27_06155(rosL)
AG: AAC68678(desVI)
 » show all
Reference
  Authors
Burgie ES, Holden HM
  Title
Three-dimensional structure of DesVI from Streptomyces venezuelae: a sugar N,N-dimethyltransferase required for dTDP-desosamine biosynthesis.
  Journal
Biochemistry 47:3982-8 (2008)
DOI:10.1021/bi800063j
Reference
PMID:9770448
  Authors
Xue Y, Zhao L, Liu HW, Sherman DH
  Title
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.
  Journal
Proc Natl Acad Sci U S A 95:12111-6 (1998)
DOI:10.1073/pnas.95.21.12111
  Sequence
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