KEGG   ORTHOLOGY: K13327
Entry
K13327                      KO                                     
Symbol
spnN, oleW
Name
dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase [EC:1.1.1.384]
Pathway
map00523  Polyketide sugar unit biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01250  Biosynthesis of nucleotide sugars
Module
M00801  dTDP-L-olivose biosynthesis
M00802  dTDP-D-forosamine biosynthesis
Reaction
R05526  dTDP-4-oxo-2,6-dideoxy-D-glucose:NADP+ 3-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K13327  spnN, oleW; dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.384  dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
     K13327  spnN, oleW; dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
Other DBs
COG: COG0673
Genes
LEZ: GLE_2525
VCX: VAA049_3443
SDE: Sde_2126
TLR: Thiosp_04675(gfo)
BGZ: XH91_11585
GUR: Gura_4277
GEO: Geob_0429
DMA: DMR_07590
DCB: C3Y92_16660
DSA: Desal_3611
LYG: C1N55_04680
PPY: PPE_03773
PPM: PPSC2_19910(gfo1)
PPO: PPM_3988(gfo1)
PPOL: X809_36015
PPQ: PPSQR21_040170
PPOY: RE92_17275
PMQ: PM3016_4486
PTA: HPL003_00790
PAEH: H70357_22130
PPEO: ABE82_19920
PBV: AR543_09655
PDH: B9T62_17435 B9T62_36235
PKB: B4V02_05395
PAIH: ASL14_17985
DMI: Desmer_4106
LBW: C3V36_01185
LCG: L3BBH23_23150
AHQ: NMU03_10405
ERB: A4V01_21325
CIU: G4D55_18800
NBR: O3I_015245
NTP: CRH09_20625
NAH: F5544_10985
NWL: NWFMUON74_25930
NIE: KV110_14285
TPR: Tpau_3482
SFI: SFUL_5283
SANL: KZO11_24430 KZO11_29555
SCYE: R2B67_24615
SCB: SCAB_84001
SRC: M271_00410
SBH: SBI_06875
SVE: SVEN_5995
SDV: BN159_2520
SALS: SLNWT_0707
SCI: B446_13495
SVT: SVTN_18810
STRE: GZL_01617
SLD: T261_6843
SLC: SL103_12595
SXI: SXIM_35770
SAMB: SAM23877_5610(srm27)
SPRI: SPRI_0254 SPRI_7099
SCX: AS200_01190
SRW: TUE45_01311(gfo_2)
SPAV: Spa2297_32820
SGS: AVL59_46220
SALW: CP975_00185
SGM: GCM10017557_73690
SPHW: NFX46_24945
SLS: SLINC_8305
SNR: SNOUR_06850
SALU: DC74_6605
SALL: SAZ_34340
SNW: BBN63_25025
SVU: B1H20_29855
SLX: SLAV_40170(afr2)
STRO: STRMOE7_07495
SFK: KY5_6078
SLK: SLUN_13815
SDX: C4B68_09685
SGD: ELQ87_00875 ELQ87_08055
SNQ: CP978_29665
STIR: DDW44_27875
SKA: CP970_10570 CP970_39860
SRK: FGW37_16320
SGAL: CP966_28985
SGF: HEP81_07919
SCAV: CVT27_24495
SPHV: F9278_28210
SCIN: CP977_27975
SPAC: B1H29_00610 B1H29_36450
STSU: B7R87_21935
SBRO: GQF42_07480
SCHF: IPT68_29235
SHUN: DWB77_05138(gfo_1)
SHAR: HUT13_24975
SCYG: S1361_04985(afr1) S1361_29925(afr3)
SDW: K7C20_32555
SCAL: I6J39_29660
SAUH: SU9_033130
SMOB: J7W19_17600
SXN: IAG42_36055
SHK: J2N69_28805
SANU: K7396_04540 K7396_33695
SDD: D9753_11225
SGOB: test1122_15660
SINE: KI385_25290
SDEC: L3078_20650
SCAE: IHE65_08930
STUB: MMF93_33235
SSPN: LXH13_14105
SCIR: STRCI_006073
STUD: STRTU_006766
SYUN: MOV08_06765
SJN: RI060_18370
SHAU: K9S39_40575
SKG: KJK29_16170
SLAI: P8A22_08975
KIS: HUT16_23830
STRI: C7M71_025690
YIA: LO772_07330
ABRY: NYE86_15405 NYE86_16015
MDB: OVN18_02320
KQI: F1D05_09195
NDA: Ndas_4698
NAL: B005_1464
NAKE: KGD83_01665
SNAH: OUQ99_30485
ACTW: F7P10_30180
AGRA: AGRA3207_007760
AMAZ: LUW76_46775
SPIQ: OHA34_04045
MMAR: MODMU_0768
SACG: FDZ84_24210
AMD: AMED_0642 AMED_5447
AMN: RAM_03280 RAM_27765
AMM: AMES_0640 AMES_5382
AMZ: B737_0641 B737_5382
AAB: A4R43_01805
AMYY: YIM_08350(afr1) YIM_11650(afr3) YIM_22845(gfo2)
APRT: MUY14_22490
AMOG: QRX60_49390
PSEH: XF36_05040
PHH: AFB00_29745(selSVI)
AMI: Amir_4534
SESP: BN6_58940(sam33)
AHM: TL08_15910
AHG: AHOG_15155(afr3) AHOG_15190(gfo1)
ACTU: Actkin_02416(perS1)
CROS: N8J89_20365
STP: Strop_2218
SAQ: Sare_1266
MAU: Micau_3990
MIL: ML5_4431
MCAB: HXZ27_04095(evdS8)
MFEU: H1D33_25595
MPRN: Q3V37_18345
PLK: CIK06_11045
DVC: Dvina_05910 Dvina_31365
DFU: Dfulv_18285 Dfulv_29105
DROS: Drose_26845
DAUR: Daura_30025
DMAT: Dmats_05390 Dmats_26460
CCAZ: COUCH_16045
AQZ: KSP35_19660
OBG: Verru16b_02068(gfo_5)
RBA: RB1063
RUL: UC8_43180(afr_5)
LKB: LPTSP3_g21190
EDA: GWR55_15425
BFR: BF0810
BFB: VU15_03405
BCEL: BcellWH2_00544(gfo_1) BcellWH2_04966(gfo_2)
ASX: CDL62_18265
FLS: GLV81_12385
RUF: TH63_02830
GFO: GFO_2034
FNK: E1750_13620
FAY: Q4Q34_07120
FBU: UJ101_00307(iolG) UJ101_00546
PROC: Ptc2401_00808(afr)
NIN: NADRNF5_2145
NIW: Nisw_04220
NUE: C5F50_00900
NBV: T478_0168
NIU: DSQ19_09595
AG: AAD55450(oleW) AAG23275(spnN) AAL14250(jadP)
 » show all
Reference
PMID:18345667
  Authors
Hong L, Zhao Z, Melancon CE 3rd, Zhang H, Liu HW
  Title
In vitro characterization of the enzymes involved in TDP-D-forosamine biosynthesis in the spinosyn pathway of Saccharopolyspora spinosa.
  Journal
J Am Chem Soc 130:4954-67 (2008)
DOI:10.1021/ja0771383
Reference
PMID:11358695
  Authors
Waldron C, Matsushima P, Rosteck PR Jr, Broughton MC, Turner J, Madduri K, Crawford KP, Merlo DJ, Baltz RH
  Title
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.
  Journal
Chem Biol 8:487-99 (2001)
DOI:10.1016/S1074-5521(01)00029-1
  Sequence
[ag:AAG23275]
Reference
PMID:10770761
  Authors
Aguirrezabalaga I, Olano C, Allende N, Rodriguez L, Brana AF, Mendez C, Salas JA
  Title
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus.
  Journal
Antimicrob Agents Chemother 44:1266-75 (2000)
DOI:10.1128/AAC.44.5.1266-1275.2000
  Sequence
[ag:AAD55450]
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